Constitutive MAP kinase activation in hematopoietic stem cells induces a myeloproliferative disorder (Q34099193)

31 July 2017

Constitutive MAP kinase activation in hematopoietic stem cells induces a myeloproliferative disorder (English)

1 reference

31 July 2017

Eva Chung

1

1 reference

31 July 2017

Chia-Lin Hsu

series ordinal

2

1 reference

31 July 2017

Motonari Kondo

series ordinal

3

1 reference

31 July 2017

language of work or name

English

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publication date

2 December 2011

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31 July 2017

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31 July 2017

6

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31 July 2017

12

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31 July 2017

e28350

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Creative Commons Attribution 4.0 International

31 July 2017

start time

2 December 2011

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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Oncogenic Kras initiates leukemia in hematopoietic stem cells

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Oncogenic Kras-induced leukemogeneis: hematopoietic stem cells as the initial target and lineage-specific progenitors as the potential targets for final leukemic transformation

5 July 2018

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Leukemia-associated NOTCH1 alleles are weak tumor initiators but accelerate K-ras-initiated leukemia

5 July 2018

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Multi-genetic events collaboratively contribute to Pten-null leukaemia stem-cell formation

5 July 2018

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Activation of mitogen-activated protein kinase kinase (MEK)/extracellular signal regulated kinase (ERK) signaling pathway is involved in myeloid lineage commitment

5 July 2018

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Differential regulation and properties of MAPKs

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Identification of a bone marrow precursor of the earliest thymocytes in adult mouse

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Oncogenes in myeloproliferative disorders

5 July 2018

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Epidemiology of hematological malignancies

5 July 2018

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Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells

5 July 2018

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Antagonistic effect of CCAAT enhancer-binding protein-alpha and Pax5 in myeloid or lymphoid lineage choice in common lymphoid progenitors

5 July 2018

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Global analysis of proliferation and cell cycle gene expression in the regulation of hematopoietic stem and progenitor cell fates

5 July 2018

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c-Myc rapidly induces acute myeloid leukemia in mice without evidence of lymphoma-associated antiapoptotic mutations.

5 July 2018

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Focus on myeloproliferative diseases and myelodysplastic syndromes

5 July 2018

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Enhancement of hematopoietic stem cell repopulating capacity and self-renewal in the absence of the transcription factor C/EBP alpha

5 July 2018

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Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia

5 July 2018

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Constitutive activation of the MEK/ERK pathway mediates all effects of oncogenic H-ras expression in primary erythroid progenitors

5 July 2018

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Somatic inactivation of Nf1 in hematopoietic cells results in a progressive myeloproliferative disorder

5 July 2018

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Conditional expression of oncogenic K-ras from its endogenous promoter induces a myeloproliferative disease

5 July 2018

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Somatic activation of oncogenic Kras in hematopoietic cells initiates a rapidly fatal myeloproliferative disorder

5 July 2018

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Signal transduction mediated by the Ras/Raf/MEK/ERK pathway from cytokine receptors to transcription factors: potential targeting for therapeutic intervention.

5 July 2018

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Map kinase signaling pathways and hematologic malignancies

5 July 2018

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BIOLOGY OF HEMATOPOIETIC STEM CELLS AND PROGENITORS: Implications for Clinical Application

5 July 2018

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Targeting RAS signalling pathways in cancer therapy

5 July 2018

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The World Health Organization (WHO) classification of the myeloid neoplasms

5 July 2018

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The phosphatidylinositol 3-Kinase AKT pathway in human cancer

5 July 2018

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Stem cells, cancer, and cancer stem cells

5 July 2018

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Effects of inducible MEK1 activation on the cytokine dependency of lymphoid cells

5 July 2018

1 reference

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c-Myc is a critical target for c/EBPalpha in granulopoiesis.

5 July 2018

1 reference

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Multiple Ras-dependent phosphorylation pathways regulate Myc protein stability.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3229546

Notch1 signaling promotes the maturation of CD4 and CD8 SP thymocytes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3229546

A conditionally-active form of MEK1 results in autocrine tranformation of human and mouse hematopoietic cells.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3229546

Cellular survival: a play in three Akts

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3229546

Ras enhances Myc protein stability.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3229546

c-Myc represses transcription in vivo by a novel mechanism dependent on the initiator element and Myc box II

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3229546

Transformation of mammalian cells by constitutively active MAP kinase kinase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3229546

Myc inhibits CCAAT/enhancer-binding protein alpha-gene expression in HIB-1B hibernoma cells through interactions with the core promoter region.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3229546

Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3229546

ras oncogenes in human cancer: a review

5 July 2018

1 reference

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Novel primitive lymphoid tumours induced in transgenic mice by cooperation between myc and bcl-2.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3229546

Cell-fate conversion of lymphoid-committed progenitors by instructive actions of cytokines

5 July 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0028350

Somatic activation of a conditional KrasG12D allele causes ineffective erythropoiesis in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0028350

DNA damage can induce apoptosis in proliferating lymphoid cells via p53-independent mechanisms inhibitable by Bcl-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0028350

Systemic overexpression of BCL-2 in the hematopoietic system protects transgenic mice from the consequences of lethal irradiation.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3229546

PTEN maintains haematopoietic stem cells and acts in lineage choice and leukaemia prevention

28 October 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0028350

10.1371/JOURNAL.PONE.0028350

21 January 2018

Identifiers

DOI

1 reference

31 July 2017

0 references

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31 July 2017

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