Crk adaptor proteins act as key signaling integrators for breast tumorigenesis (Q36245357)

13 August 2017

Crk adaptor proteins act as key signaling integrators for breast tumorigenesis (English)

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13 August 2017

Anne-Marie Mes-Masson

object named as

Anne-Marie Mes-Masson

10

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author name string

Kelly E Fathers

1

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13 August 2017

Emily S Bell

2

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13 August 2017

Charles V Rajadurai

3

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13 August 2017

Sean Cory

4

1 reference

13 August 2017

Hong Zhao

5

1 reference

13 August 2017

Anna Mourskaia

6

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13 August 2017

Dongmei Zuo

7

1 reference

13 August 2017

Jason Madore

8

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13 August 2017

Anie Monast

9

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13 August 2017

Andree-Anne Grosset

11

1 reference

13 August 2017

Louis Gaboury

12

1 reference

13 August 2017

Michael Hallet

13

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13 August 2017

Peter Siegel

14

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13 August 2017

Morag Park

15

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13 August 2017

8 May 2012

1 reference

13 August 2017

Breast Cancer Research

1 reference

13 August 2017

14

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13 August 2017

3

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13 August 2017

R74

1 reference

describes a project that uses

13 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3446336/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

exact match

https://scigraph.springernature.com/pub.10.1186/bcr3183

0 references

cites work

miR-126 functions as a tumour suppressor in human gastric cancer

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Overexpression of galectin-7, a myoepithelial cell marker, enhances spontaneous metastasis of breast cancer cells.

1 October 2017

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CrkII transgene induces atypical mammary gland development and tumorigenesis

1 October 2017

1 reference

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Integrin beta1-focal adhesion kinase signaling directs the proliferation of metastatic cancer cells disseminated in the lungs

1 October 2017

1 reference

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Supervised risk predictor of breast cancer based on intrinsic subtypes

1 October 2017

1 reference

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Predicting prognosis using molecular profiling in estrogen receptor-positive breast cancer treated with tamoxifen

1 October 2017

1 reference

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Human breast cancer cell lines contain stem-like cells that self-renew, give rise to phenotypically diverse progeny and survive chemotherapy

1 October 2017

1 reference

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Trio mediates netrin-1-induced Rac1 activation in axon outgrowth and guidance.

1 October 2017

1 reference

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Endogenous human microRNAs that suppress breast cancer metastasis

1 October 2017

1 reference

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Increased tumor cell dissemination and cellular senescence in the absence of beta1-integrin function

1 October 2017

1 reference

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Oncogenic activation of the Met receptor tyrosine kinase fusion protein, Tpr-Met, involves exclusion from the endocytic degradative pathway.

1 October 2017

1 reference

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A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes

1 October 2017

1 reference

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p130Cas: a versatile scaffold in signaling networks

1 October 2017

1 reference

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Involvement of adaptor protein Crk in malignant feature of human ovarian cancer cell line MCAS.

1 October 2017

1 reference

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Beta1 integrin inhibitory antibody induces apoptosis of breast cancer cells, inhibits growth, and distinguishes malignant from normal phenotype in three dimensional cultures and in vivo

1 October 2017

1 reference

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Heterogeneity of Tie2 expression in tumor microcirculation: influence of cancer type, implantation site, and response to therapy

1 October 2017

1 reference

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Probing tumor phenotypes using stable and regulated synthetic microRNA precursors

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446336

Genes that mediate breast cancer metastasis to lung

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446336

The adapter protein CrkII regulates neuronal Wiskott-Aldrich syndrome protein, actin polymerization, and tension development during contractile stimulation of smooth muscle

1 October 2017

1 reference

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Gene-expression profiles to predict distant metastasis of lymph-node-negative primary breast cancer

1 October 2017

1 reference

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CrkII regulates focal adhesion kinase activation by making a complex with Crk-associated substrate, p130Cas

1 October 2017

1 reference

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Bioconductor: open software development for computational biology and bioinformatics

1 October 2017

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Regulation of integrin-mediated cellular responses through assembly of a CAS/Crk scaffold.

1 October 2017

1 reference

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Involvement of Ras activation in human breast cancer cell signaling, invasion, and anoikis

1 October 2017

1 reference

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Oncogenic Ras and its role in tumor cell invasion and metastasis

1 October 2017

1 reference

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Molecular basis for Rho GTPase signaling specificity

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446336

CrkII induces serum response factor activation and cellular transformation through its function in Rho activation

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446336

A multigenic program mediating breast cancer metastasis to bone

1 October 2017

1 reference

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A gene-expression signature as a predictor of survival in breast cancer

1 October 2017

1 reference

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Tyrosine 221 in Crk regulates adhesion-dependent membrane localization of Crk and Rac and activation of Rac signaling

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446336

Crk synergizes with epidermal growth factor for epithelial invasion and morphogenesis and is required for the met morphogenic program

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446336

Crk adapter proteins promote an epithelial-mesenchymal-like transition and are required for HGF-mediated cell spreading and breakdown of epithelial adherens junctions

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446336

Molecular and immunohistochemical analysis of signaling adaptor protein Crk in human cancers

1 October 2017

1 reference

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Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications

1 October 2017

1 reference

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Structural requirements for function of the Crkl adapter protein in fibroblasts and hematopoietic cells

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446336

CAS/Crk coupling serves as a "molecular switch" for induction of cell migration

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446336

Cdc42 regulates anchorage-independent growth and is necessary for Ras transformation

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446336

Reversion of the malignant phenotype of human breast cells in three-dimensional culture and in vivo by integrin blocking antibodies

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446336

The CRKL adaptor protein transforms fibroblasts and functions in transformation by the BCR-ABL oncogene

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446336

Rho, rac and cdc42 GTPases: regulators of actin structures, cell adhesion and motility

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446336

A novel viral oncogene with structural similarity to phospholipase C

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446336

Identification of domains of the v-crk oncogene product sufficient for association with phosphotyrosine-containing proteins

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446336

Binding of Transforming Protein, P47 gag-crk , to a Broad Range of Phosphotyrosine-containing Proteins

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446336

Association of the v-crk oncogene product with phosphotyrosine-containing proteins and protein kinase activity

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446336

Two species of human CRK cDNA encode proteins with distinct biological activities

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446336

Transforming growth factor-beta1 is the predominant isoform required for breast cancer cell outgrowth in bone

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446336

Genetic reclassification of histologic grade delineates new clinical subtypes of breast cancer.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446336

Adaptor molecule Crk is required for sustained phosphorylation of Grb2-associated binder 1 and hepatocyte growth factor-induced cell motility of human synovial sarcoma cell lines

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446336

CrkI and CrkII function as key signaling integrators for migration and invasion of cancer cells.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446336

Increased C-CRK proto-oncogene expression is associated with an aggressive phenotype in lung adenocarcinomas

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446336

CrkI adapter protein modulates cell migration and invasion in glioblastoma

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446336

Crkl enhances leukemogenesis in BCR/ABL P190 transgenic mice.

22 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22569336

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1186/BCR3183

1 reference

Dimensions Publication ID

13 August 2017

0 references

1 reference

13 August 2017

1 reference