Sclerostin antibody treatment improves fracture outcomes in a Type I diabetic mouse model (Q36253807)

13 August 2017

Sclerostin antibody treatment improves fracture outcomes in a Type I diabetic mouse model (English)

1 reference

13 August 2017

1 reference

6

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11 June 2020

Gabriela G Loots

7

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11 June 2020

author name string

Cristal S Yee

1

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11 June 2020

LiQin Xie

2

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11 June 2020

Sarah Hatsell

3

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11 June 2020

Nicholas Hum

4

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11 June 2020

Deepa Murugesh

5

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11 June 2020

Nicole M Collette

8

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11 June 2020

publication date

4 May 2015

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13 August 2017

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11 June 2020

volume

82

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11 June 2020

page(s)

122-134

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describes a project that uses

11 June 2020

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4635060/fullTextXML

inferred from PubMed Central ID database lookup

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30 September 2017

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The C-terminal fragment of parathyroid hormone-related peptide promotes bone formation in diabetic mice with low-turnover osteopaenia

30 September 2017

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Systemic administration of sclerostin monoclonal antibody accelerates fracture healing in the femoral osteotomy model of young rats.

29 June 2018

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Sclerostin deficiency is linked to altered bone composition

22 September 2018

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Zinc supplementation inhibits the increase in osteoclastogenesis and decrease in osteoblastogenesis in streptozotocin-induced diabetic rats

22 September 2018

1 reference

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Exendin-4 increases bone mineral density in type 2 diabetic OLETF rats potentially through the down-regulation of SOST/sclerostin in osteocytes.

22 September 2018

1 reference

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Sclerostin antibody treatment improves bone mass, bone strength, and bone defect regeneration in rats with type 2 diabetes mellitus.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4635060

Effects of sclerostin antibody on healing of a non-critical size femoral bone defect

22 September 2018

1 reference

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Sclerostin levels associated with inhibition of the Wnt/β-catenin signaling and reduced bone turnover in type 2 diabetes mellitus

22 September 2018

1 reference

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Management of diabetes mellitus: could simultaneous targeting of hyperglycemia and oxidative stress be a better panacea?

22 September 2018

1 reference

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Insulin-dependent diabetes mellitus decreases osteoblastogenesis associated with the inhibition of Wnt signaling through increased expression of Sost and Dkk1 and inhibition of Akt activation.

22 September 2018

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The bone marrow microenvironment contributes to type I diabetes induced osteoblast death

22 September 2018

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Prevalence and predictors of osteopenia and osteoporosis in adults with Type 1 diabetes

22 September 2018

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Diabetes and its complications and their relationship with risk of fractures in type 1 and 2 diabetes

22 September 2018

1 reference

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Targeted deletion of the sclerostin gene in mice results in increased bone formation and bone strength

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4635060

22 September 2018

1 reference

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Histomorphometric analysis of diabetic osteopenia in streptozotocin-induced diabetic mice: a possible role of oxidative stress.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4635060

Bone mineral density and fracture risk in type-2 diabetes mellitus: the Rotterdam Study

22 September 2018

1 reference

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The effects of blood glucose control upon fracture healing in the BB Wistar rat with diabetes mellitus

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4635060

Inhibition of sclerostin by systemic treatment with sclerostin antibody enhances healing of proximal tibial defects in ovariectomized rats

22 September 2018

1 reference

12 December 2020

Inhibition of sclerostin by monoclonal antibody enhances bone healing and improves bone density and strength of nonfractured bones

1 reference

12 December 2020

Intensive insulin therapy and bone mineral density in type 1 diabetes mellitus: a prospective study

1 reference

12 December 2020

Production of a standard closed fracture in laboratory animal bone

1 reference

12 December 2020

Increased callus mass and enhanced strength during fracture healing in mice lacking the sclerostin gene

1 reference

12 December 2020

Temporal changes in systemic and local expression of bone turnover markers during six months of sclerostin antibody administration to ovariectomized rats

1 reference

12 December 2020

Diabetes interferes with the bone formation by affecting the expression of transcription factors that regulate osteoblast differentiation

1 reference

12 December 2020

Hyperglycemia enhances adipogenic induction of lipid accumulation: involvement of extracellular signal-regulated protein kinase 1/2, phosphoinositide 3-kinase/Akt, and peroxisome proliferator-activated receptor gamma signaling

1 reference

12 December 2020

Sclerostin monoclonal antibody enhanced bone fracture healing in an open osteotomy model in rats

1 reference

12 December 2020

Bone Loss and Increased Bone Adiposity in Spontaneous and Pharmacologically Induced Diabetic Mice

1 reference

12 December 2020

Bone matrix quality after sclerostin antibody treatment

1 reference

12 December 2020

Circulating sclerostin levels and bone turnover in type 1 and type 2 diabetes

1 reference

12 December 2020

An in vivo experimental study on osteopenia in diabetic rats

1 reference

12 December 2020

10.1016/J.BONE.2015.04.048

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25952969%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25952969%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25952969%20AND%20SRC:MED&resulttype=core&format=json