Immunological thresholds in neurological gene therapy: highly efficient elimination of transduced cells might be related to the specific formation of immunological synapses between T cells and virus-infected brain cells. (Q36274402)

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English	Immunological thresholds in neurological gene therapy: highly efficient elimination of transduced cells might be related to the specific formation of immunological synapses between T cells and virus-infected brain cells.	scientific article

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29 December 2019

Immunological thresholds in neurological gene therapy: highly efficient elimination of transduced cells might be related to the specific formation of immunological synapses between T cells and virus-infected brain cells (English)

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29 December 2019

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29 December 2019

Maria G. Castro

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29 December 2019

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Christian Gerdes

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29 December 2019

Wei-Dong Xiong

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29 December 2019

Clare E Thomas

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29 December 2019

Chunyan Liu

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29 December 2019

Kurt M Kroeger

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29 December 2019

Pedro R Lowenstein

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29 December 2019

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1 November 2006

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29 December 2019

Neuron Glia Biology

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29 December 2019

2

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29 December 2019

4

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29 December 2019

309-322

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29 December 2019

In vivo mature immunological synapses forming SMACs mediate clearance of virally infected astrocytes from the brain

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Human cytomegalovirus infection activates and regulates the unfolded protein response

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Corticostriatopallidal neuroprotection by adenovirus-mediated ciliary neurotrophic factor gene transfer in a rat model of progressive striatal degeneration

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Adenoviruses encoding HPRT correct the biochemical abnormalities fully only in HPRT-deficient human cell lines: importance of species differences.

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Towards a neuroprotective gene therapy for Parkinson's disease: use of adenovirus, AAV and lentivirus vectors for gene transfer of GDNF to the nigrostriatal system in the rat Parkinson model

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Peripheral infection with adenovirus causes unexpected long-term brain inflammation in animals injected intracranially with first-generation, but not with high-capacity, adenovirus vectors: toward realistic long-term neurological gene therapy for ch

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Intrastriatal injection of an adenoviral vector expressing glial-cell-line-derived neurotrophic factor prevents dopaminergic neuron degeneration and behavioral impairment in a rat model of Parkinson disease.

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Effects of ectopic decorin in modulating intracranial glioma progression in vivo, in a rat syngeneic model

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The double-stranded RNA-activated protein kinase mediates viral-induced encephalitis

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Continuous delivery of neurotrophin 3 by gene therapy has a neuroprotective effect in experimental models of diabetic and acrylamide neuropathies

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Central nervous system toxicity of two adenoviral vectors encoding variants of the herpes simplex virus type 1 thymidine kinase: reduced cytotoxicity of a truncated HSV1-TK.

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A paracrine paradigm for in vivo gene therapy in the central nervous system: treatment of chronic pain.

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Immunological instability of persistent adenovirus vectors in the brain: peripheral exposure to vector leads to renewed inflammation, reduced gene expression, and demyelination

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AdvHSV-tk gene therapy with intravenous ganciclovir improves survival in human malignant glioma: a randomised, controlled study

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22 September 2018

Adenovirus-mediated expression of antisense urokinase plasminogen activator receptor and antisense cathepsin B inhibits tumor growth, invasion, and angiogenesis in gliomas

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22 September 2018

Long-term transgene expression can be mediated in the brain by adenoviral vectors when powerful neuron-specific promoters are used

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22 September 2018

Preexisting antiadenoviral immunity is not a barrier to efficient and stable transduction of the brain, mediated by novel high-capacity adenovirus vectors

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22 September 2018

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22 September 2018

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The unbiased estimation of number and sizes of arbitrary particles using the disector

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adenovirus gene transfer causes inflammation in the brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/18084640

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1017/S1740925X07000579

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18084640%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

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Europe PubMed Central

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29 December 2019

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Europe PubMed Central

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29 December 2019

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