Cyclodextrin mediates rapid changes in lipid balance in Npc1-/- mice without carrying cholesterol through the bloodstream. (Q36302736)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22892156%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

title

Cyclodextrin mediates rapid changes in lipid balance in Npc1-/- mice without carrying cholesterol through the bloodstream (English)

1 reference

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11 February 2020

1

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11 February 2020

author name string

Bing Liu

2

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11 February 2020

Yelenis Mari

3

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11 February 2020

Benny Liu

4

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11 February 2020

Joyce J Repa

5

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11 February 2020

language of work or name

1 reference

14 August 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22892156%20AND%20SRC:MED&resulttype=core&format=json

Journal of Lipid Research

11 February 2020

published in

1 reference

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11 February 2020

volume

53

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11 February 2020

issue

11

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11 February 2020

page(s)

2331-2342

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Normalization of cholesterol homeostasis by 2-hydroxypropyl-β-cyclodextrin in neurons and glia from Niemann-Pick C1 (NPC1)-deficient mice

11 February 2020

cites work

1 reference

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30 September 2017

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Molecular mechanism of cyclodextrin mediated cholesterol extraction

30 September 2017

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Quantitative role of LAL, NPC2, and NPC1 in lysosomal cholesterol processing defined by genetic and pharmacological manipulations

30 September 2017

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30 September 2017

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30 September 2017

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2-hydroxypropyl-beta-cyclodextrin raises hearing threshold in normal cats and in cats with Niemann-Pick type C disease

30 September 2017

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Endocytosis of beta-cyclodextrins is responsible for cholesterol reduction in Niemann-Pick type C mutant cells

30 September 2017

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Cyclodextrin overcomes the transport defect in nearly every organ of NPC1 mice leading to excretion of sequestered cholesterol as bile acid

30 September 2017

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Cyclodextrin overcomes deficient lysosome-to-endoplasmic reticulum transport of cholesterol in Niemann-Pick type C cells

30 September 2017

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Chronic cyclodextrin treatment of murine Niemann-Pick C disease ameliorates neuronal cholesterol and glycosphingolipid storage and disease progression

30 September 2017

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Structure of N-Terminal Domain of NPC1 Reveals Distinct Subdomains for Binding and Transfer of Cholesterol

30 September 2017

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Reversal of defective lysosomal transport in NPC disease ameliorates liver dysfunction and neurodegeneration in the npc1-/- mouse

30 September 2017

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Analyzing real-time PCR data by the comparative C(T) method

30 September 2017

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30 September 2017

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Use of cyclodextrins to manipulate plasma membrane cholesterol content: evidence, misconceptions and control strategies

30 September 2017

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Pregnane X receptor (PXR) activation: a mechanism for neuroprotection in a mouse model of Niemann-Pick C disease

30 September 2017

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2-Hydroxypropyl-beta-cyclodextrin (HP-beta-CD): a toxicology review

30 September 2017

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Quantitative real-time polymerase chain reaction measurement of regulators of G-protein signaling mRNA levels in mouse tissues

30 September 2017

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A riddle wrapped in a mystery: understanding Niemann-Pick disease, type C.

30 September 2017

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Coordinated transcription of key pathways in the mouse by the circadian clock

30 September 2017

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Cyclodextrins as catalysts for the removal of cholesterol from macrophage foam cells

30 September 2017

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Cyclodextrins--enabling excipients: their present and future use in pharmaceuticals.

30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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29 June 2018

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29 June 2018

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29 June 2018

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29 June 2018

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22 September 2018

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Imatinib therapy blocks cerebellar apoptosis and improves neurological symptoms in a mouse model of Niemann-Pick type C disease

22 September 2018

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Liver X receptor activation enhances cholesterol loss from the brain, decreases neuroinflammation, and increases survival of the NPC1 mouse.

22 September 2018

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22 September 2018

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Caveolin-1 is not required for murine intestinal cholesterol transport.

22 September 2018

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22 September 2018

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Apoptosis accompanied by up-regulation of TNF-alpha death pathway genes in the brain of Niemann-Pick type C disease.

22 September 2018

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Validation of housekeeping genes for normalizing RNA expression in real-time PCR.

22 September 2018

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Critical role for glycosphingolipids in Niemann-Pick disease type C.

22 September 2018

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Cholesterol is sequestered in the brains of mice with Niemann-Pick type C disease but turnover is increased.

22 September 2018

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Alternate transcripts expressed in response to diet reflect tissue-specific regulation of ABCA1

22 September 2018

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Lysosomal unesterified cholesterol content correlates with liver cell death in murine Niemann-Pick type C disease

5 December 2018

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12 December 2020

Measurement of rates of cholesterol synthesis using tritiated water

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12 December 2020

Reevaluation and application of the dual-isotope plasma ratio method for the measurement of intestinal cholesterol absorption in the hamster

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12 December 2020

Preliminary safety evaluation of parenterally administered sulfoalkyl ether beta-cyclodextrin derivatives

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Identifiers

DOI

10.1194/JLR.M028241

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22892156%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22892156%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

1 reference