Apaf-1 and caspase-9 do not act as tumor suppressors in myc-induced lymphomagenesis or mouse embryo fibroblast transformation. (Q36321735)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14709542%20AND%20SRC:MED&resulttype=core&format=json

17 November 2019

title

Apaf-1 and caspase-9 do not act as tumor suppressors in myc-induced lymphomagenesis or mouse embryo fibroblast transformation (English)

1 reference

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17 November 2019

4

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17 November 2019

Marc Pellegrini

5

1 reference

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17 November 2019

Stephen L. Nutt

8

1 reference

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17 November 2019

Douglas R. Green

9

1 reference

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17 November 2019

Andreas Strasser

10

1 reference

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17 November 2019

author name string

Clare L Scott

1

1 reference

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17 November 2019

Martin Schuler

2

1 reference

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17 November 2019

Vanessa S Marsden

3

1 reference

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17 November 2019

Dobrila Nesic

6

1 reference

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17 November 2019

Steve Gerondakis

7

1 reference

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17 November 2019

language of work or name

English

0 references

publication date

1 January 2004

1 reference

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17 November 2019

number of pages

8

1 reference

inferred from page(s)

published in

Journal of Cell Biology

1 reference

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17 November 2019

volume

164

1 reference

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17 November 2019

issue

1

1 reference

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17 November 2019

page(s)

89-96

1 reference

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Apoptosis initiated by Bcl-2-regulated caspase activation independently of the cytochrome c/Apaf-1/caspase-9 apoptosome

17 November 2019

cites work

1 reference

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c-MYC: more than just a matter of life and death

30 September 2017

1 reference

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Dissecting p53 tumor suppressor functions in vivo

30 September 2017

1 reference

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The expanding role of mitochondria in apoptosis

30 September 2017

1 reference

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Apaf-1 protein deficiency confers resistance to cytochrome c-dependent apoptosis in human leukemic cells

30 September 2017

1 reference

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Inactivation of the apoptosis effector Apaf-1 in malignant melanoma

30 September 2017

1 reference

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Role of BAX in the apoptotic response to anticancer agents

30 September 2017

1 reference

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The biochemistry of apoptosis

30 September 2017

1 reference

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30 September 2017

1 reference

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Apoptotic protease activating factor 1 (Apaf-1)-independent cell death suppression by Bcl-2.

30 September 2017

1 reference

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INK4a/ARF mutations accelerate lymphomagenesis and promote chemoresistance by disabling p53.

30 September 2017

1 reference

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Disruption of the ARF-Mdm2-p53 tumor suppressor pathway in Myc-induced lymphomagenesis

30 September 2017

1 reference

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Apaf1 is required for mitochondrial pathways of apoptosis and brain development

30 September 2017

1 reference

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Apaf1 (CED-4 homolog) regulates programmed cell death in mammalian development

30 September 2017

1 reference

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Mitochondria and apoptosis

30 September 2017

1 reference

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Differential requirement for caspase 9 in apoptotic pathways in vivo.

30 September 2017

1 reference

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Reduced apoptosis and cytochrome c-mediated caspase activation in mice lacking caspase 9

30 September 2017

1 reference

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Autoactivation of procaspase-9 by Apaf-1-mediated oligomerization

30 September 2017

1 reference

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Bim: a novel member of the Bcl-2 family that promotes apoptosis

30 September 2017

1 reference

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bax-deficiency promotes drug resistance and oncogenic transformation by attenuating p53-dependent apoptosis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171953

Inhibition of Ced-3/ICE-related proteases does not prevent cell death induced by oncogenes, DNA damage, or the Bcl-2 homologue Bak

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171953

Progenitor tumours from Emu-bcl-2-myc transgenic mice have lymphomyeloid differentiation potential and reveal developmental differences in cell survival

30 September 2017

1 reference

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Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells

30 September 2017

1 reference

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The E mu-myc transgenic mouse. A model for high-incidence spontaneous lymphoma and leukemia of early B cells

30 September 2017

1 reference

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Long-term proliferating early pre B cell lines and clones with the potential to develop to surface Ig-positive, mitogen reactive B cells in vitro and in vivo.

30 September 2017

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Cooperative interaction between c-myc and bcl-2 proto-oncogenes

30 September 2017

1 reference

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Apoptotic cell death induced by c-myc is inhibited by bcl-2.

30 September 2017

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Novel primitive lymphoid tumours induced in transgenic mice by cooperation between myc and bcl-2.

30 September 2017

1 reference

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Apaf-1 and caspase-9 in p53-dependent apoptosis and tumor inhibition.

29 June 2018

1 reference

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Caspase-9 and Apaf-1 are expressed and functionally active in human neuroblastoma tumor cell lines with 1p36 LOH and amplified MYCN.

21 January 2018

1 reference

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Evidence that c-myc mediated apoptosis does not require wild-type p53 during lymphomagenesis.

21 January 2018

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The c-myc oncogene driven by immunoglobulin enhancers induces lymphoid malignancy in transgenic mice

22 September 2018

2 references

https://api.crossref.org/works/10.1083%2FJCB.200310041

21 January 2018

https://pubmed.ncbi.nlm.nih.gov/14709542

12 December 2020

inferred from PubMed ID database lookup

The c-myc oncogene perturbs B lymphocyte development in Eμ-myc transgenic mice

2 references

https://api.crossref.org/works/10.1083%2FJCB.200310041

21 January 2018

https://pubmed.ncbi.nlm.nih.gov/14709542

12 December 2020

inferred from PubMed ID database lookup

Caspase-2 is not required for thymocyte or neuronal apoptosis even though cleavage of caspase-2 is dependent on both Apaf-1 and caspase-9

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200310041

Deficiency in caspase-9 or caspase-3 induces compensatory caspase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200310041

Common ALL with pre-B-cell features showing (8;14) and (14;18) chromosome translocations

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/14709542

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1083/JCB.200310041

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14709542%20AND%20SRC:MED&resulttype=core&format=json

17 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14709542%20AND%20SRC:MED&resulttype=core&format=json

17 November 2019

1 reference