Safety and Biologic Response of Pre-operative Autophagy Inhibition in Combination with Gemcitabine in Patients with Pancreatic Adenocarcinoma (Q36329393)

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English	Safety and Biologic Response of Pre-operative Autophagy Inhibition in Combination with Gemcitabine in Patients with Pancreatic Adenocarcinoma	scientific article

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scholarly article

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Europe PubMed Central

PMC publication ID

13 August 2017

Safety and Biologic Response of Pre-operative Autophagy Inhibition in Combination with Gemcitabine in Patients with Pancreatic Adenocarcinoma (English)

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Europe PubMed Central

PMC publication ID

13 August 2017

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25905586%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Daniel P. Normolle

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10 June 2020

Virginia Espina

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10 June 2020

David L Bartlett

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David L Bartlett

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10 June 2020

Herbert J. Zeh, III

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Herbert J Zeh

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10 June 2020

Michael T Lotze

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Michael T Lotze

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10 June 2020

Amer H Zureikat

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Amer H Zureikat

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10 June 2020

Lance A. Liotta

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Lance A Liotta

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10 June 2020

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Nathan Bahary

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10 June 2020

A James Moser

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10 June 2020

Wen-Chi Wu

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10 June 2020

Aatur D Singhi

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10 June 2020

Phillip Bao

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10 June 2020

Patricia Loughran

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10 June 2020

publication date

24 April 2015

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13 August 2017

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9

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Annals of Surgical Oncology

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10 June 2020

22

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10 June 2020

13

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10 June 2020

4402-4410

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25905586%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

A phase I/II trial of hydroxychloroquine in conjunction with radiation therapy and concurrent and adjuvant temozolomide in patients with newly diagnosed glioblastoma multiforme

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30 September 2017

Phase I trial of hydroxychloroquine with dose-intense temozolomide in patients with advanced solid tumors and melanoma

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30 September 2017

Combined MTOR and autophagy inhibition: phase I trial of hydroxychloroquine and temsirolimus in patients with advanced solid tumors and melanoma

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30 September 2017

Phase I clinical trial and pharmacodynamic evaluation of combination hydroxychloroquine and doxorubicin treatment in pet dogs treated for spontaneously occurring lymphoma

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30 September 2017

Combined autophagy and HDAC inhibition: a phase I safety, tolerability, pharmacokinetic, and pharmacodynamic analysis of hydroxychloroquine in combination with the HDAC inhibitor vorinostat in patients with advanced solid tumors

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30 September 2017

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30 September 2017

Autophagy is critical for pancreatic tumor growth and progression in tumors with p53 alterations

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30 September 2017

Phase II and pharmacodynamic study of autophagy inhibition using hydroxychloroquine in patients with metastatic pancreatic adenocarcinoma

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30 September 2017

Targeting ER stress-induced autophagy overcomes BRAF inhibitor resistance in melanoma.

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30 September 2017

Autophagy is needed for the growth of pancreatic adenocarcinoma and has a cytoprotective effect against anticancer drugs

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30 September 2017

Having pancreatic cancer with tumoral loss of ATM and normal TP53 protein expression is associated with a poorer prognosis.

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30 September 2017

Strange attractors: DAMPs and autophagy link tumor cell death and immunity

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30 September 2017

p53 status determines the role of autophagy in pancreatic tumour development

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30 September 2017

Increased survival in pancreatic cancer with nab-paclitaxel plus gemcitabine

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30 September 2017

The autophagy inhibitor verteporfin moderately enhances the antitumor activity of gemcitabine in a pancreatic ductal adenocarcinoma model

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30 September 2017

Interplay between autophagy and apoptosis in pancreatic tumors in response to gemcitabine

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30 September 2017

Guidelines for the use and interpretation of assays for monitoring autophagy

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30 September 2017

Microscopic margins and patterns of treatment failure in resected pancreatic adenocarcinoma

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30 September 2017

Autophagy in pancreatic cancer pathogenesis and treatment

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30 September 2017

Autophagic activity dictates the cellular response to oncogenic RAS.

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30 September 2017

Carbohydrate antigen 19-9 is a prognostic and predictive biomarker in patients with advanced pancreatic cancer who receive gemcitabine-containing chemotherapy: a pooled analysis of 6 prospective trials

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30 September 2017

AGER/RAGE-mediated autophagy promotes pancreatic tumorigenesis and bioenergetics through the IL6-pSTAT3 pathway

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30 September 2017

The expression of the receptor for advanced glycation endproducts (RAGE) is permissive for early pancreatic neoplasia

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30 September 2017

Cell-mediated autophagy promotes cancer cell survival.

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30 September 2017

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30 September 2017

Tumor-cell death, autophagy, and immunity

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30 September 2017

Computational modeling of pancreatic cancer reveals kinetics of metastasis suggesting optimum treatment strategies

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30 September 2017

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30 September 2017

Autophagy suppression promotes apoptotic cell death in response to inhibition of the PI3K-mTOR pathway in pancreatic adenocarcinoma

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30 September 2017

FOLFIRINOX versus gemcitabine for metastatic pancreatic cancer

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CA19-9 as a predictor of tumor response and survival in patients with advanced pancreatic cancer treated with gemcitabine based chemotherapy

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Enhancer of zeste homolog 2 downregulates E-cadherin by mediating histone H3 methylation in gastric cancer cells

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Autophagy and cancer therapy

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Autophagy, p53, and Pancreatic Cancer

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https://pubmed.ncbi.nlm.nih.gov/25905586

12 December 2020

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RAGE regulates autophagy and apoptosis following oxidative injury

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12 December 2020

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Apoptosis to autophagy switch triggered by the MHC class III-encoded receptor for advanced glycation endproducts (RAGE)

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12 December 2020

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Preoperative chemoradiation and pancreaticoduodenectomy for adenocarcinoma of the pancreas

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https://pubmed.ncbi.nlm.nih.gov/25905586

12 December 2020

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10.1245/S10434-015-4566-4

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10 June 2020

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10 June 2020

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10 June 2020

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