Distinct cellular pathways select germline-encoded and somatically mutated antibodies into immunological memory. (Q36340852)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23027924%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

title

Distinct cellular pathways select germline-encoded and somatically mutated antibodies into immunological memory (English)

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9 March 2020

1 reference

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8

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9 March 2020

Osamu Ohara

11

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9 March 2020

Klaus Rajewsky

12

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9 March 2020

author name string

Tomohiro Kaji

1

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9 March 2020

Akiko Ishige

2

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9 March 2020

Masaki Hikida

3

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9 March 2020

Junko Taka

4

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9 March 2020

Atsushi Hijikata

5

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9 March 2020

Masato Kubo

6

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9 March 2020

Takeshi Nagashima

7

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9 March 2020

Tomohiro Kurosaki

9

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9 March 2020

Mariko Okada

10

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9 March 2020

Toshitada Takemori

13

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9 March 2020

language of work or name

English

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publication date

1 October 2012

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Journal of Experimental Medicine

9 March 2020

published in

1 reference

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9 March 2020

volume

209

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9 March 2020

issue

11

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9 March 2020

page(s)

2079-2097

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A germinal center-independent pathway generates unswitched memory B cells early in the primary response

9 March 2020

cites work

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Different B cell populations mediate early and late memory during an endogenous immune response

30 September 2017

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Germinal center dynamics revealed by multiphoton microscopy with a photoactivatable fluorescent reporter

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Plasticity and heterogeneity in the generation of memory B cells and long-lived plasma cells: the influence of germinal center interactions and dynamics.

30 September 2017

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BCL6: master regulator of the germinal center reaction and key oncogene in B cell lymphomagenesis

30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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IL-21 regulates germinal center B cell differentiation and proliferation through a B cell-intrinsic mechanism

30 September 2017

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30 September 2017

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Systematic comparison of gene expression between murine memory and naive B cells demonstrates that memory B cells have unique signaling capabilities

30 September 2017

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Visualizing spatiotemporal dynamics of multicellular cell-cycle progression

30 September 2017

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How do adjuvants work? Important considerations for new generation adjuvants

30 September 2017

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Transcriptional profiling of antigen-dependent murine B cell differentiation and memory formation

30 September 2017

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New markers for murine memory B cells that define mutated and unmutated subsets

30 September 2017

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B-cell memory: are subsets necessary?

30 September 2017

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Testing gene function early in the B cell lineage in mb1-cre mice

30 September 2017

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ROKU: a novel method for identification of tissue-specific genes

30 September 2017

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Tracking germinal center B cells expressing germ-line immunoglobulin gamma1 transcripts by conditional gene targeting

30 September 2017

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The NR4A subgroup: immediate early response genes with pleiotropic physiological roles

30 September 2017

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T-independent type II immune responses generate memory B cells

30 September 2017

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Early appearance of germinal center-derived memory B cells and plasma cells in blood after primary immunization.

30 September 2017

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The role of suppressors of cytokine signaling (SOCS) proteins in regulation of the immune response

30 September 2017

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Memory B cells without somatic hypermutation are generated from Bcl6-deficient B cells

30 September 2017

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Modes of action of Freund's adjuvants in experimental models of autoimmune diseases

30 September 2017

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Distinct roles of Jun : Fos and Jun : ATF dimers in oncogenesis

30 September 2017

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CD40-CD40L independent Ig gene hypermutation suggests a second B cell diversification pathway in humans

30 September 2017

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Commitment of B lymphocytes to a plasma cell fate is associated with Blimp-1 expression in vivo

30 September 2017

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Ras mediates effector pathways responsible for pre-B cell survival, which is essential for the developmental progression to the late pre-B cell stage

30 September 2017

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Unmutated Ig V(H) genes are associated with a more aggressive form of chronic lymphocytic leukemia.

30 September 2017

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The BCL-6 proto-oncogene controls germinal-centre formation and Th2-type inflammation

30 September 2017

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Control of inflammation, cytokine expression, and germinal center formation by BCL-6

30 September 2017

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Clonal selection and learning in the antibody system

30 September 2017

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M17: a novel gene expressed in germinal centers.

30 September 2017

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The immune responses in CD40-deficient mice: impaired immunoglobulin class switching and germinal center formation

30 September 2017

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Isolation of high-affinity memory B cells: phycoerythrin as a probe for antigen-binding cells

30 September 2017

1 reference

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The repertoire of somatic antibody mutants accumulating in the memory compartment after primary immunization is restricted through affinity maturation and mirrors that expressed in the secondary response

30 September 2017

1 reference

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Analysis of the repertoire of anti-(4-hydroxy-3-nitro-phenyl)acetyl (NP) antibodies in C 57 BL/6 mice by cell fusion. II. Characterization of idiotopes by monoclonal anti-idiotope antibodies

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478929

Transcriptional repressor BCL6 controls Th17 responses by controlling gene expression in both T cells and macrophages

30 September 2017

1 reference

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Novel role of the Ras cascade in memory B cell response.

29 June 2018

1 reference

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Targeted disruption of the MHC class II Aa gene in C57BL/6 mice

29 June 2018

1 reference

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Antibody engineering for the analysis of affinity maturation of an anti-hapten response.

29 June 2018

1 reference

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Bcl6 protein expression shapes pre-germinal center B cell dynamics and follicular helper T cell heterogeneity.

29 June 2018

1 reference

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Bcl6 is required for the development of mouse CD4+ and CD8α+ dendritic cells.

22 September 2018

1 reference

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Multiple layers of B cell memory with different effector functions

22 September 2018

1 reference

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Antigen affinity controls rapid T-dependent antibody production by driving the expansion rather than the differentiation or extrafollicular migration of early plasmablasts.

22 September 2018

1 reference

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Initial clonal expansion of germinal center B cells takes place at the perimeter of follicles

22 September 2018

1 reference

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High-efficiency CAG-FLPe deleter mice in C57BL/6J background.

22 September 2018

1 reference

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Pvclust: an R package for assessing the uncertainty in hierarchical clustering.

22 September 2018

1 reference

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Two waves of memory B-cell generation in the primary immune response.

22 September 2018

1 reference

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Role of antigen receptor affinity in T cell-independent antibody responses in vivo

22 September 2018

1 reference

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Resolution of three nonproliferative immature splenic B cell subsets reveals multiple selection points during peripheral B cell maturation

22 September 2018

1 reference

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Fas is required for clonal selection in germinal centers and the subsequent establishment of the memory B cell repertoire

22 September 2018

1 reference

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BCL-6 represses genes that function in lymphocyte differentiation, inflammation, and cell cycle control.

22 September 2018

1 reference

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Identification of murine germinal center B cell subsets defined by the expression of surface isotypes and differentiation antigens.

22 September 2018

1 reference

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Kinetics of establishing the memory B cell population as revealed by CD38 expression.

22 September 2018

1 reference

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In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl. V. Affinity maturation develops in two stages of clonal selection.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478929

Evidence for a large compartment of IgM-expressing memory B cells in humans.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3478929

Accumulation of somatic hypermutation and antigen-driven selection in rapidly cycling surface Ig+ germinal center (GC) B cells which occupy GC at a high frequency during the primary anti-hapten response in mice

22 September 2018

1 reference

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22 September 2018

Identifiers

DOI

10.1084/JEM.20120127

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23027924%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23027924%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

PubMed publication ID

23027924

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23027924%20AND%20SRC:MED&resulttype=core&format=json