Transforming growth factor beta blocks Tec kinase phosphorylation, Ca2+ influx, and NFATc translocation causing inhibition of T cell differentiation (Q36370893)

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English	Transforming growth factor beta blocks Tec kinase phosphorylation, Ca2+ influx, and NFATc translocation causing inhibition of T cell differentiation	scientific article

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scholarly article

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Europe PubMed Central

PMC publication ID

13 August 2017

Transforming growth factor beta blocks Tec kinase phosphorylation, Ca2+ influx, and NFATc translocation causing inhibition of T cell differentiation (English)

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

phosphorylation

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cell differentiation

1 reference

based on heuristic

inferred from title

Carole Seguin-Devaux

2

object named as

Carole Seguin-Devaux

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author name string

Chang-Hung Chen

1

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Europe PubMed Central

PMC publication ID

13 August 2017

Nancy A Burke

3

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Europe PubMed Central

PMC publication ID

13 August 2017

Timothy B Oriss

4

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Simon C Watkins

5

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Europe PubMed Central

PMC publication ID

13 August 2017

Neil Clipstone

6

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Europe PubMed Central

PMC publication ID

13 August 2017

Anuradha Ray

7

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Europe PubMed Central

PMC publication ID

13 August 2017

language of work or name

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publication date

1 June 2003

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Europe PubMed Central

PMC publication ID

13 August 2017

Journal of Experimental Medicine

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Europe PubMed Central

PMC publication ID

13 August 2017

197

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Europe PubMed Central

PMC publication ID

13 August 2017

12

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

1689-1699

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Two-photon tissue imaging: seeing the immune system in a fresh light

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193945

30 September 2017

Mechanism of transforming growth factor beta-induced inhibition of T helper type 1 differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193945

30 September 2017

Distinct effects of T-bet in TH1 lineage commitment and IFN-gamma production in CD4 and CD8 T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193945

30 September 2017

Transcriptional regulation of Th1/Th2 polarization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193945

30 September 2017

Cyclic AMP activates p38 mitogen-activated protein kinase in Th2 cells: phosphorylation of GATA-3 and stimulation of Th2 cytokine gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193945

30 September 2017

Role of Tec kinase in nuclear factor of activated T cells signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193945

30 September 2017

Transient inhibition of interleukin 4 signaling by T cell receptor ligation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193945

30 September 2017

Lineage commitment in the immune system: the T helper lymphocyte grows up.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193945

30 September 2017

Signaling and transcription in T helper development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193945

30 September 2017

JNK is required for effector T-cell function but not for T-cell activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193945

30 September 2017

Tec family kinases in lymphocyte signaling and function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193945

30 September 2017

A novel transcription factor, T-bet, directs Th1 lineage commitment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193945

30 September 2017

Identification of amino acid residues and protein kinases involved in the regulation of NFATc subcellular localization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193945

30 September 2017

Biochemical interactions integrating Itk with the T cell receptor-initiated signaling cascade

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193945

30 September 2017

CD4(+) T helper cells engineered to produce latent TGF-beta1 reverse allergen-induced airway hyperreactivity and inflammation

1 reference

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30 September 2017

TGF-beta1: immunosuppressant and viability factor for T lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193945

30 September 2017

Inhibition of allergic inflammation in a murine model of asthma by expression of a dominant-negative mutant of GATA-3

2 references

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30 September 2017

https://api.crossref.org/works/10.1084%2FJEM.20021170

21 January 2018

Th2 cells and GATA-3 in asthma: new insights into the regulation of airway inflammation

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30 September 2017

Itk/Emt/Tsk activation in response to CD3 cross-linking in Jurkat T cells requires ZAP-70 and Lat and is independent of membrane recruitment

1 reference

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30 September 2017

The transcription factor c-Maf controls the production of interleukin-4 but not other Th2 cytokines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193945

30 September 2017

The IL-4 receptor: signaling mechanisms and biologic functions

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30 September 2017

Transcriptional regulation of T lymphocyte development and function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193945

30 September 2017

Requirement for Tec kinases Rlk and Itk in T cell receptor signaling and immunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193945

30 September 2017

rlk/TXK encodes two forms of a novel cysteine string tyrosine kinase activated by Src family kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193945

30 September 2017

Essential role of nuclear factor kappaB in the induction of eosinophilia in allergic airway inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193945

30 September 2017

Low dose TGF-beta attenuates IL-12 responsiveness in murine Th cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193945

30 September 2017

T cell receptor-initiated calcium release is uncoupled from capacitative calcium entry in Itk-deficient T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193945

30 September 2017

Phosphatidylinositol-3,4,5-trisphosphate (PtdIns-3,4,5-P3)/Tec kinase-dependent calcium signaling pathway: a target for SHIP-mediated inhibitory signals

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193945

30 September 2017

The transcription factor NF-ATc1 regulates lymphocyte proliferation and Th2 cytokine production

1 reference

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30 September 2017

Transcription factor GATA-3 is differentially expressed in murine Th1 and Th2 cells and controls Th2-specific expression of the interleukin-5 gene

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193945

30 September 2017

The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193945

30 September 2017

Differential activation of transcription factors induced by Ca2+ response amplitude and duration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193945

30 September 2017

Nuclear export of NF-ATc enhanced by glycogen synthase kinase-3

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193945

30 September 2017

Rapid shuttling of NF-AT in discrimination of Ca2+ signals and immunosuppression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193945

30 September 2017

Role of kinases and the phosphatase calcineurin in the nuclear shuttling of transcription factor NF-AT4.

1 reference

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30 September 2017

Calcineurin binds the transcription factor NFAT1 and reversibly regulates its activity

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193945

30 September 2017

GATA transcription factors associate with a novel class of nuclear bodies in erythroblasts and megakaryocytes

1 reference

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30 September 2017

The EMT/ITK/TSK (EMT) tyrosine kinase is activated during TCR signaling: LCK is required for optimal activation of EMT.

1 reference

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Leptomycin B targets a regulatory cascade of crm1, a fission yeast nuclear protein, involved in control of higher order chromosome structure and gene expression

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30 September 2017

Production of transforming growth factor beta by human T lymphocytes and its potential role in the regulation of T cell growth

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30 September 2017

A model for receptor-regulated calcium entry

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30 September 2017

Flow cytometric measurement of cytoplasmic free calcium in human peripheral blood T lymphocytes with fluo-3, a new fluorescent calcium indicator.

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30 September 2017

Targeted disruption of the mouse transforming growth factor-beta 1 gene results in multifocal inflammatory disease

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30 September 2017

Impaired NFATc translocation and failure of Th2 development in Itk-deficient CD4+ T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193945

28 June 2018

Selective loss of the calcium ion signaling pathway in T cells maturing toward a T helper 2 phenotype.

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28 June 2018

Nuclear factor of activated T cells contains Fos and Jun.

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28 June 2018

Sustained NFAT signaling promotes a Th1-like pattern of gene expression in primary murine CD4+ T cells

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21 September 2018

Cutting edge: TGF-beta inhibits Th type 2 development through inhibition of GATA-3 expression.

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Blockade of transforming growth factor beta/Smad signaling in T cells by overexpression of Smad7 enhances antigen-induced airway inflammation and airway reactivity

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21 September 2018

PtdIns-3,4,5-P3: a regulatory nexus between tyrosine kinases and sustained calcium signals

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21 September 2018

Efficient CD28 signalling leads to increases in the kinase activities of the TEC family tyrosine kinase EMT/ITK/TSK and the SRC family tyrosine kinase LCK.

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The duration of nuclear residence of NFAT determines the pattern of cytokine expression in human SCID T cells

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The effect of TGF-beta1 on immune responses of naïve versus memory CD4+ Th1/Th2 T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12810687

12 December 2020

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inferred from PubMed ID database lookup

TGF-β1 down-regulates Th2 development and results in decreased IL-4-induced STAT6 activation and GATA-3 expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/12810687

12 December 2020

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inferred from PubMed ID database lookup

A critical role for NF-kappa B in GATA3 expression and TH2 differentiation in allergic airway inflammation

1 reference

https://pubmed.ncbi.nlm.nih.gov/12810687

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutation of Tec family kinases alters T helper cell differentiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/12810687

12 December 2020

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inferred from PubMed ID database lookup

Single IL-2-secreting precursor CD4 T cell can develop into either Th1 or Th2 cytokine secretion phenotype

1 reference

https://pubmed.ncbi.nlm.nih.gov/12810687

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inferred from PubMed ID database lookup

TGF-beta induced by oral tolerance ameliorates experimental tracheal eosinophilia

1 reference

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Interaction of NF-kappaB and NFAT with the interferon-gamma promoter

1 reference

https://pubmed.ncbi.nlm.nih.gov/12810687

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Abrogation of TGFbeta signaling in T cells leads to spontaneous T cell differentiation and autoimmune disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/12810687

12 December 2020

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inferred from PubMed ID database lookup

Delayed lymphoid repopulation with defects in IL-4-driven responses produced by inactivation of NF-ATc

1 reference

https://pubmed.ncbi.nlm.nih.gov/12810687

12 December 2020

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The roles of nuclear factor of activated T cells and ying-yang 1 in activation-induced expression of the interferon-gamma promoter in T cells

1 reference

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12 December 2020

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10.1084/JEM.20021170

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

release_lwnxoqkpwbae3mhk3qf7qjh5te

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24 November 2022

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PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

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13 August 2017

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