Dual suppression of the cyclin-dependent kinase inhibitors CDKN2C and CDKN1A in human melanoma. (Q36376583)

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13 February 2020

title

Dual suppression of the cyclin-dependent kinase inhibitors CDKN2C and CDKN1A in human melanoma (English)

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13 February 2020

6

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13 February 2020

Mathieu Lupien

7

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Georg Stingl

1 reference

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13 February 2020

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Todd R Golub

1 reference

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13 February 2020

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David E Fisher

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13 February 2020

author name string

Ahmad Jalili

1

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13 February 2020

Christine Wagner

2

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13 February 2020

Mikhail Pashenkov

3

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13 February 2020

Gaurav Pathria

4

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13 February 2020

Kirsten D Mertz

5

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13 February 2020

Jean-Philippe Brunet

8

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13 February 2020

Sridhar Ramaswamy

12

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13 February 2020

Stephan N Wagner

13

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13 February 2020

language of work or name

English

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publication date

20 September 2012

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Journal of the National Cancer Institute

13 February 2020

published in

1 reference

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13 February 2020

volume

104

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13 February 2020

issue

21

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13 February 2020

page(s)

1673-1679

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Improved survival with vemurafenib in melanoma with BRAF V600E mutation

13 February 2020

cites work

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Dissecting therapeutic resistance to RAF inhibition in melanoma by tumor genomic profiling

30 September 2017

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Acquired resistance to BRAF inhibitors mediated by a RAF kinase switch in melanoma can be overcome by cotargeting MEK and IGF-1R/PI3K

30 September 2017

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Melanomas acquire resistance to B-RAF(V600E) inhibition by RTK or N-RAS upregulation

30 September 2017

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COT drives resistance to RAF inhibition through MAP kinase pathway reactivation

30 September 2017

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Clinical efficacy of a RAF inhibitor needs broad target blockade in BRAF-mutant melanoma

30 September 2017

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Inhibition of Mutated, Activated BRAF in Metastatic Melanoma

30 September 2017

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An oncogenic role for ETV1 in melanoma

30 September 2017

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Antitumor efficacy of the novel RAF inhibitor GDC-0879 is predicted by BRAFV600E mutational status and sustained extracellular signal-regulated kinase/mitogen-activated protein kinase pathway suppression.

30 September 2017

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Role of mitogen-activated protein kinase kinase kinases in signal integration

30 September 2017

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Rewired ERK-JNK signaling pathways in melanoma

30 September 2017

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Genome-wide analysis of estrogen receptor binding sites

30 September 2017

1 reference

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Distinct sets of genetic alterations in melanoma

30 September 2017

1 reference

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Mitf cooperates with Rb1 and activates p21Cip1 expression to regulate cell cycle progression

30 September 2017

1 reference

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Activation of protein kinase C promotes human cancer cell growth through downregulation of p18(INK4c).

30 September 2017

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AP-1: a double-edged sword in tumorigenesis

30 September 2017

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Invasive melanoma in Cdk4-targeted mice

30 September 2017

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Dominant negative c-jun inhibits activation of the cyclin D1 and cyclin E kinase complexes

30 September 2017

1 reference

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The p16 status of tumor cell lines identifies small molecule inhibitors specific for cyclin-dependent kinase 4

30 September 2017

1 reference

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Blockade of the MAP kinase pathway suppresses growth of colon tumors in vivo

30 September 2017

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MEK inhibitors: the chemistry and biological activity of U0126, its analogs, and cyclization products

30 September 2017

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CVT-313, a specific and potent inhibitor of CDK2 that prevents neointimal proliferation

30 September 2017

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Cyclin kinase inhibitor p21WAF1/CIP1 in malignant melanoma: reduced expression in metastatic lesions

30 September 2017

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30 September 2017

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Genetic cooperation between p21Cip1 and INK4 inhibitors in cellular senescence and tumor suppression.

30 September 2017

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Spontaneous and UV radiation-induced multiple metastatic melanomas in Cdk4R24C/R24C/TPras mice.

21 January 2018

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Release of cell cycle constraints in mouse melanocytes by overexpressed mutant E2F1E132, but not by deletion of p16INK4A or p21WAF1/CIP1.

21 January 2018

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Potentiation of paclitaxel-induced apoptosis by the novel cyclin-dependent kinase inhibitor NU6140: a possible role for survivin down-regulation.

21 January 2018

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Synthesis, Structure−Activity Relationship, and Biological Studies of Indolocarbazoles as Potent Cyclin D1-CDK4 Inhibitors

21 January 2018

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A c-Jun dominant negative mutant protects sympathetic neurons against programmed cell death

21 January 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/22997239

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

CDKN2A (P16(INK4a)) and CDK4 mutation analysis in 131 Australian melanoma probands: effect of family history and multiple primary melanomas

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22997239

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1093/JNCI/DJS373

1 reference

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13 February 2020

1 reference

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13 February 2020

PubMed publication ID

22997239

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22997239%20AND%20SRC:MED&resulttype=core&format=json