Matrix metalloproteinase 9-induced increase in intestinal epithelial tight junction permeability contributes to the severity of experimental DSS colitis (Q36382078)

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English	Matrix metalloproteinase 9-induced increase in intestinal epithelial tight junction permeability contributes to the severity of experimental DSS colitis	scientific article

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28 February 2020

Matrix metalloproteinase 9-induced increase in intestinal epithelial tight junction permeability contributes to the severity of experimental DSS colitis (English)

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28 February 2020

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28 February 2020

Daniel Watterson

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28 February 2020

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Prashant Nighot

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28 February 2020

Rana Al-Sadi

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28 February 2020

Shuhong Guo

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28 February 2020

Thomas Ma

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28 February 2020

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29 October 2015

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28 February 2020

American Journal of Physiology - Gastrointestinal and Liver Physiology

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28 February 2020

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28 February 2020

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28 February 2020

G988-97

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28 February 2020

Chloride channel ClC-2 is a key factor in the development of DSS-induced murine colitis.

1 reference

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30 September 2017

TNFR2 activates MLCK-dependent tight junction dysregulation to cause apoptosis-mediated barrier loss and experimental colitis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4683300

30 September 2017

Mechanism of interleukin-1β induced-increase in mouse intestinal permeability in vivo

1 reference

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30 September 2017

Enterocyte STAT5 promotes mucosal wound healing via suppression of myosin light chain kinase-mediated loss of barrier function and inflammation

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30 September 2017

CXCR4 antagonist AMD3100 modulates claudin expression and intestinal barrier function in experimental colitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4683300

30 September 2017

Correlation of MMP-3 and MMP-9 with Crohn's disease activity in children

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30 September 2017

MicroRNA regulation of intestinal epithelial tight junction permeability

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4683300

30 September 2017

Matrix metalloproteinase-9 inhibition reduces inflammation and improves motility in murine models of postoperative ileus

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30 September 2017

Colon-specific delivery of a probiotic-derived soluble protein ameliorates intestinal inflammation in mice through an EGFR-dependent mechanism

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30 September 2017

Occludin regulates macromolecule flux across the intestinal epithelial tight junction barrier

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4683300

30 September 2017

Epithelial myosin light chain kinase activation induces mucosal interleukin-13 expression to alter tight junction ion selectivity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4683300

30 September 2017

Matrix metalloproteinase-9 mediates hypoxia-induced vascular leakage in the brain via tight junction rearrangement

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4683300

30 September 2017

Intestinal mucosal barrier function in health and disease

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30 September 2017

Normobaric hyperoxia attenuates early blood-brain barrier disruption by inhibiting MMP-9-mediated occludin degradation in focal cerebral ischemia

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30 September 2017

Matrix metalloproteinase-9-mediated tissue injury overrides the protective effect of matrix metalloproteinase-2 during colitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4683300

30 September 2017

Targeted epithelial tight junction dysfunction causes immune activation and contributes to development of experimental colitis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4683300

30 September 2017

Reducing small intestinal permeability attenuates colitis in the IL10 gene-deficient mouse

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30 September 2017

Claudin-1 and claudin-2 expression is elevated in inflammatory bowel disease and may contribute to early neoplastic transformation

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4683300

30 September 2017

TGF-beta1 induced MMP-9 expression in HNSCC cell lines via Smad/MLCK pathway

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4683300

30 September 2017

Matrix metalloproteinases in inflammatory bowel disease: boon or a bane?

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30 September 2017

Attenuation of dextran sodium sulphate induced colitis in matrix metalloproteinase-9 deficient mice.

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30 September 2017

Targeted deletion of metalloproteinase 9 attenuates experimental colitis in mice: central role of epithelial-derived MMP.

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30 September 2017

Myosin light chain kinase is involved in lipopolysaccharide-induced disruption of colonic epithelial barrier and bacterial translocation in rats.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4683300

30 September 2017

Role of matrix metalloproteinases in inflammatory bowel disease

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4683300

30 September 2017

A differentiation-dependent splice variant of myosin light chain kinase, MLCK1, regulates epithelial tight junction permeability

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4683300

30 September 2017

Overlapping and independent contributions of MMP2 and MMP9 to lung allergic inflammatory cell egression through decreased CC chemokines

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30 September 2017

Protein kinase involved in lung injury susceptibility: evidence from enzyme isoform genetic knockout and in vivo inhibitor treatment

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30 September 2017

Increased activity and expression of matrix metalloproteinase-9 in a rat model of distal colitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4683300

30 September 2017

Neutrophil gelatinase B potentiates interleukin-8 tenfold by aminoterminal processing, whereas it degrades CTAP-III, PF-4, and GRO-alpha and leaves RANTES and MCP-2 intact.

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30 September 2017

Ethanol modulation of intestinal epithelial tight junction barrier

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30 September 2017

Enteropathogenic Escherichia coli-induced myosin light chain phosphorylation alters intestinal epithelial permeability

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30 September 2017

A synthetic peptide corresponding to the extracellular domain of occludin perturbs the tight junction permeability barrier

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30 September 2017

Occludin is a functional component of the tight junction.

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30 September 2017

Constitutive expression of MMP9 in intestinal epithelium worsens murine acute colitis and is associated with increased levels of proinflammatory cytokine Kc.

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28 June 2018

Chloride channel ClC-2 modulates tight junction barrier function via intracellular trafficking of occludin.

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28 June 2018

Chemically induced mouse models of intestinal inflammation

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28 June 2018

MicroRNA-21 knockout improve the survival rate in DSS induced fatal colitis through protecting against inflammation and tissue injury

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21 September 2018

Myosin light chain kinase inhibitor inhibits dextran sulfate sodium-induced colitis in mice

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21 September 2018

Fecal MMP-9: a new noninvasive differential diagnostic and activity marker in ulcerative colitis

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21 September 2018

HIV-1 Tat protein increases the permeability of brain endothelial cells by both inhibiting occludin expression and cleaving occludin via matrix metalloproteinase-9.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4683300

21 September 2018

Suppression of MMP-9 expression in brain microvascular endothelial cells (BMVEC) using a gold nanorod (GNR)-siRNA nanoplex

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21 September 2018

The behavior of matrix metalloproteinase-9 in lymphocytic colitis, collagenous colitis and ulcerative colitis.

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21 September 2018

Probiotic mixture VSL#3 protects the epithelial barrier by maintaining tight junction protein expression and preventing apoptosis in a murine model of colitis.

1 reference

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21 September 2018

Changes in the expression of claudins in active ulcerative colitis.

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21 September 2018

Myosin light chain kinase inhibition: correction of increased intestinal epithelial permeability in vitro.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4683300

21 September 2018

Actin polymerization modulates CD44 surface expression, MMP-9 activation, and osteoclast function.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4683300

21 September 2018

Prostaglandin-mediated inhibition of Na+/H+ exchanger isoform 2 stimulates recovery of barrier function in ischemia-injured intestine.

1 reference

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21 September 2018

Matrix metalloproteinase-9 modulates intestinal injury in rats with transmural colitis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4683300

21 September 2018

Molecular mechanism of tumor necrosis factor-alpha modulation of intestinal epithelial tight junction barrier

1 reference

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21 September 2018

Mechanism of TNF-{alpha} modulation of Caco-2 intestinal epithelial tight junction barrier: role of myosin light-chain kinase protein expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4683300

21 September 2018

Knockdown of occludin expression leads to diverse phenotypic alterations in epithelial cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4683300

21 September 2018

Cytochalasin B modulation of Caco-2 tight junction barrier: role of myosin light chain kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4683300

21 September 2018

Induction of matrix metalloproteinase-9 requires a polymerized actin cytoskeleton in human malignant glioma cells

1 reference

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21 September 2018

Myosin light chain phosphorylation regulates barrier function by remodeling tight junction structure

1 reference

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21 January 2018

The Impact of Matrix Metalloproteinases and Their Tissue Inhibitors in Inflammatory Bowel Diseases

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00256.2015

21 January 2018

Increased incidence of urinary matrix metalloproteinases as predictors of disease in pediatric patients with inflammatory bowel disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/26514773

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased mucosal matrix metalloproteinase-1, -2, -3 and -9 activity in patients with inflammatory bowel disease and the relation with Crohn's disease phenotype

1 reference

https://pubmed.ncbi.nlm.nih.gov/26514773

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apical junction complex protein expression in the canine colon: differential expression of claudin-2 in the colonic mucosa in dogs with idiopathic colitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/26514773

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective up-regulation of claudin-1 and claudin-2 in colorectal cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/26514773

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serum MMPs 7-9 and their inhibitors during glucocorticoid and anti-TNF-α therapy in pediatric inflammatory bowel disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/26514773

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Abnormal intestinal permeability predicts relapse in inactive Crohn disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/26514773

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intestinal permeability and the prediction of relapse in Crohn's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/26514773

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Physiological regulation of epithelial tight junctions is associated with myosin light-chain phosphorylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/26514773

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epithelial myosin light chain kinase expression and activity are upregulated in inflammatory bowel disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/26514773

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1152/AJPGI.00256.2015

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26514773%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26514773%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26514773%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

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