Enterocyte STAT5 promotes mucosal wound healing via suppression of myosin light chain kinase-mediated loss of barrier function and inflammation (Q35836695)

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scientific article published on 9 January 2012

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English	Enterocyte STAT5 promotes mucosal wound healing via suppression of myosin light chain kinase-mediated loss of barrier function and inflammation	scientific article published on 9 January 2012

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scholarly article

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Europe PubMed Central

PMC publication ID

10 August 2017

Enterocyte STAT5 promotes mucosal wound healing via suppression of myosin light chain kinase-mediated loss of barrier function and inflammation (English)

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Europe PubMed Central

PMC publication ID

10 August 2017

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Noah F. Shroyer

object named as

Noah Shroyer

6

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object named as

Xiaonan Han

8

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Richard Moriggl

object named as

Richard Moriggl

4

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author name string

Shila Gilbert

1

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Europe PubMed Central

PMC publication ID

10 August 2017

Rongli Zhang

2

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Europe PubMed Central

PMC publication ID

10 August 2017

Lee Denson

3

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Europe PubMed Central

PMC publication ID

10 August 2017

Kris Steinbrecher

5

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Europe PubMed Central

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10 August 2017

James Lin

7

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Europe PubMed Central

PMC publication ID

10 August 2017

publication date

9 January 2012

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Europe PubMed Central

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10 August 2017

EMBO Molecular Medicine

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Europe PubMed Central

PMC publication ID

10 August 2017

4

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Europe PubMed Central

PMC publication ID

10 August 2017

2

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Europe PubMed Central

PMC publication ID

10 August 2017

109-124

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Europe PubMed Central

PMC publication ID

10 August 2017

describes a project that uses

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Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3306555/fullTextXML

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Interferon-γ-induced increases in intestinal epithelial macromolecular permeability requires the Src kinase Fyn.

1 reference

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Loss of guanylyl cyclase C (GCC) signaling leads to dysfunctional intestinal barrier

1 reference

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Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47

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Tight Junction Pore and Leak Pathways: A Dynamic Duo

1 reference

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Loss of GM-CSF signalling in non-haematopoietic cells increases NSAID ileal injury

1 reference

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MLCK-dependent exchange and actin binding region-dependent anchoring of ZO-1 regulate tight junction barrier function

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Caveolin-1-dependent occludin endocytosis is required for TNF-induced tight junction regulation in vivo

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1 reference

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Targeted epithelial tight junction dysfunction causes immune activation and contributes to development of experimental colitis.

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ZO-1- and ZO-2-dependent integration of myosin-2 to epithelial zonula adherens

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Early embryonic lethality of mice lacking ZO-2, but Not ZO-3, reveals critical and nonredundant roles for individual zonula occludens proteins in mammalian development

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IFN-gamma-induced TNFR2 expression is required for TNF-dependent intestinal epithelial barrier dysfunction

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Tumor necrosis factor-induced long myosin light chain kinase transcription is regulated by differentiation-dependent signaling events. Characterization of the human long myosin light chain kinase promoter

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Changes in expression and distribution of claudin 2, 5 and 8 lead to discontinuous tight junctions and barrier dysfunction in active Crohn's disease

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Role of epithelial cells in initiation and propagation of intestinal inflammation. Eliminating the static: tight junction dynamics exposed

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Epithelial myosin light chain kinase-dependent barrier dysfunction mediates T cell activation-induced diarrhea in vivo

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Interferon-gamma and tumor necrosis factor-alpha synergize to induce intestinal epithelial barrier dysfunction by up-regulating myosin light chain kinase expression

1 reference

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A differentiation-dependent splice variant of myosin light chain kinase, MLCK1, regulates epithelial tight junction permeability

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TNF-alpha-induced increase in intestinal epithelial tight junction permeability requires NF-kappa B activation

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1 reference

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Myosin light chain phosphorylation regulates barrier function by remodeling tight junction structure

1 reference

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Interleukin-10 gene-deficient mice develop a primary intestinal permeability defect in response to enteric microflora

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https://pubmed.ncbi.nlm.nih.gov/22228679

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NAD+ ameliorates inflammation-induced epithelial barrier dysfunction in cultured enterocytes and mouse ileal mucosa

1 reference

https://pubmed.ncbi.nlm.nih.gov/22228679

12 December 2020

based on heuristic

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Increased intestinal permeability in patients with Crohn's disease and their relatives. A possible etiologic factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/22228679

12 December 2020

based on heuristic

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Local administration of antisense phosphorothioate oligonucleotides to the p65 subunit of NF-kappa B abrogates established experimental colitis in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/22228679

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based on heuristic

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Physiological regulation of epithelial tight junctions is associated with myosin light-chain phosphorylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/22228679

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based on heuristic

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Epithelial myosin light chain kinase expression and activity are upregulated in inflammatory bowel disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/22228679

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1002/EMMM.201100192

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

ResearchGate publication ID

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