Deficient DNA damage signaling leads to chemoresistance to cisplatin in oral cancer (Q36392876)

13 August 2017

Deficient DNA damage signaling leads to chemoresistance to cisplatin in oral cancer (English)

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lip and oral cavity carcinoma

13 August 2017

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3

Gregory G Oakley

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13 August 2017

Ling Wang

1

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13 August 2017

Adam J Mosel

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2

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13 August 2017

Aimin Peng

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4

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13 August 2017

12 September 2012

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Molecular Cancer Therapeutics

13 August 2017

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13 August 2017

11

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13 August 2017

11

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13 August 2017

2401-2409

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describes a project that uses

13 August 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3496048/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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The Role of Wild-Type p53 in Cisplatin-Induced Chk2 Phosphorylation and the Inhibition of Platinum Resistance with a Chk2 Inhibitor

30 September 2017

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30 September 2017

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Wip1 promotes RUNX2-dependent apoptosis in p53-negative tumors and protects normal tissues during treatment with anticancer agents

30 September 2017

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Activation of DNA damage response pathways in human mesenchymal stem cells exposed to cisplatin or γ-irradiation

30 September 2017

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30 September 2017

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The oncogenic phosphatase PPM1D confers cisplatin resistance in ovarian carcinoma cells by attenuating checkpoint kinase 1 and p53 activation.

30 September 2017

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Molecular mechanisms of cisplatin resistance

30 September 2017

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Greatwall and Polo-like kinase 1 coordinate to promote checkpoint recovery

30 September 2017

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hMSH2 recruits ATR to DNA damage sites for activation during DNA damage-induced apoptosis

30 September 2017

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Serine/threonine phosphatases in the DNA damage response and cancer

30 September 2017

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Arsenic trioxide - An old drug rediscovered

30 September 2017

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Nuclear factor-kappaB (NF-kappaB) is a novel positive transcriptional regulator of the oncogenic Wip1 phosphatase

30 September 2017

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WIP1 phosphatase at the crossroads of cancer and aging

30 September 2017

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Hyperphosphorylation of replication protein A in cisplatin-resistant and -sensitive head and neck squamous cell carcinoma cell lines

30 September 2017

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Genotyping of 73 UM-SCC head and neck squamous cell carcinoma cell lines

30 September 2017

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The combined status of ATM and p53 link tumor development with therapeutic response

30 September 2017

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The estrogen receptor alpha pathway induces oncogenic Wip1 phosphatase gene expression

30 September 2017

1 reference

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Biological responses to arsenic compounds

30 September 2017

1 reference

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Downregulation of Wip-1 phosphatase expression in MCF-7 breast cancer cells enhances doxorubicin-induced apoptosis through p53-mediated transcriptional activation of Bax.

30 September 2017

1 reference

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The type 2C phosphatase Wip1: an oncogenic regulator of tumor suppressor and DNA damage response pathways.

30 September 2017

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A chemical inhibitor of PPM1D that selectively kills cells overexpressing PPM1D.

30 September 2017

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Loss of distal 11q is associated with DNA repair deficiency and reduced sensitivity to ionizing radiation in head and neck squamous cell carcinoma.

30 September 2017

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Arsenic derivatives in hematologic malignancies: a role beyond acute promyelocytic leukemia?

30 September 2017

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Recent advances in head and neck cancer therapy: the role of new cytotoxic and molecular-targeted agents.

30 September 2017

1 reference

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TopBP1 activates the ATR-ATRIP complex

30 September 2017

1 reference

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The Mre11 complex is required for ATM activation and the G2/M checkpoint

30 September 2017

1 reference

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ATM gene and lymphoid malignancies

30 September 2017

1 reference

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Requirement of the MRN complex for ATM activation by DNA damage

30 September 2017

1 reference

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Targeting DNA checkpoint kinases in cancer therapy

30 September 2017

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Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes

30 September 2017

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30 September 2017

1 reference

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Wip1, a novel human protein phosphatase that is induced in response to ionizing radiation in a p53-dependent manner

30 September 2017

1 reference

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Measurement of drug-induced DNA interstrand crosslinking using the single-cell gel electrophoresis (comet) assay.

30 September 2017

1 reference

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Lower ataxia telangiectasia mutated (ATM) mRNA expression is correlated with poor outcome of laryngeal and pharyngeal cancer patients

21 September 2018

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Arsenic trioxide augments Chk2/p53-mediated apoptosis by inhibiting oncogenic Wip1 phosphatase

21 September 2018

1 reference

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ATM in oral carcinogenesis: association with clinicopathological features.

21 September 2018

1 reference

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Mutation status of the residual ATM allele is an important determinant of the cellular response to chemotherapy and survival in patients with chronic lymphocytic leukemia containing an 11q deletion.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3496048

Genetic abnormalities and clinical outcome in chronic lymphocytic leukemia.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3496048

Reversal of cisplatin resistance with a BH3 mimetic, (-)-gossypol, in head and neck cancer cells: role of wild-type p53 and Bcl-xL.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3496048

P53 mutation correlates with cisplatin sensitivity in head and neck squamous cell carcinoma lines

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3496048

ATM gene deletion in patients with adult acute lymphoblastic leukemia

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3496048

10.1158/1535-7163.MCT-12-0448

21 September 2018

Identifiers

DOI

1 reference

13 August 2017

1 reference

13 August 2017

PubMed publication ID

22973056

1 reference