XBP-1 specifically promotes IgM synthesis and secretion, but is dispensable for degradation of glycoproteins in primary B cells (Q36402768)

14 August 2017

XBP-1 specifically promotes IgM synthesis and secretion, but is dispensable for degradation of glycoproteins in primary B cells (English)

1 reference

14 August 2017

4

Hidde L Ploegh

1 reference

14 August 2017

3

Laurie H Glimcher

1 reference

14 August 2017

2

Neal N Iwakoshi

1 reference

14 August 2017

Boaz Tirosh

1

1 reference

PMCID

2212843

14 August 2017

language of work or name

English

0 references

publication date

1 August 2005

1 reference

Journal of Experimental Medicine

14 August 2017

1 reference

14 August 2017

202

1 reference

14 August 2017

4

1 reference

14 August 2017

505-516

1 reference

PMCID

2212843

describes a project that uses

14 August 2017

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2212843/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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XBP1: a link between the unfolded protein response, lipid biosynthesis, and biogenesis of the endoplasmic reticulum.

30 September 2017

1 reference

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XBP1, downstream of Blimp-1, expands the secretory apparatus and other organelles, and increases protein synthesis in plasma cell differentiation

30 September 2017

1 reference

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XBP-1 Regulates a Subset of Endoplasmic Reticulum Resident Chaperone Genes in the Unfolded Protein Response

30 September 2017

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The X-box binding protein-1 transcription factor is required for plasma cell differentiation and the unfolded protein response

30 September 2017

1 reference

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Plasma cell differentiation and the unfolded protein response intersect at the transcription factor XBP-1

30 September 2017

1 reference

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Sequential waves of functionally related proteins are expressed when B cells prepare for antibody secretion

30 September 2017

1 reference

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Regulatory mechanisms that determine the development and function of plasma cells

30 September 2017

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Transcriptional and translational control in the Mammalian unfolded protein response

30 September 2017

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30 September 2017

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IRE1-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response

30 September 2017

1 reference

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IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA

30 September 2017

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Plasma cell differentiation requires the transcription factor XBP-1

30 September 2017

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Signal peptide cleavage of a type I membrane protein, HCMV US11, is dependent on its membrane anchor

30 September 2017

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Functional and genomic analyses reveal an essential coordination between the unfolded protein response and ER-associated degradation

30 September 2017

1 reference

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Proteases involved in MHC class II antigen presentation

30 September 2017

1 reference

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Stress signaling from the lumen of the endoplasmic reticulum: coordination of gene transcriptional and translational controls

30 September 2017

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Dislocation of type I membrane proteins from the ER to the cytosol is sensitive to changes in redox potential

30 September 2017

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The transmembrane kinase Ire1p is a site-specific endonuclease that initiates mRNA splicing in the unfolded protein response

30 September 2017

1 reference

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Signal sequence-dependent function of the TRAM protein during early phases of protein transport across the endoplasmic reticulum membrane

30 September 2017

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30 September 2017

1 reference

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CpG motifs in bacterial DNA trigger direct B-cell activation

30 September 2017

1 reference

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30 September 2017

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Activation of an unfolded protein response during differentiation of antibody-secreting B cells.

30 September 2017

1 reference

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Normal isotype switching in B cells lacking the I mu exon splice donor site: evidence for multiple I mu-like germline transcripts.

28 June 2018

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Molecular components of the B-cell antigen receptor complex of the IgM class.

28 June 2018

1 reference

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Reduction of interchain disulfide bonds precedes the dislocation of Ig-mu chains from the endoplasmic reticulum to the cytosol for proteasomal degradation

28 June 2018

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Cytosolic degradation of T-cell receptor alpha chains by the proteasome

21 September 2018

1 reference

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Role of Sec61alpha in the regulated transfer of the ribosome-nascent chain complex from the signal recognition particle to the translocation channel

21 September 2018

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12 December 2020

Degradation of proteins from the ER of S. cerevisiae requires an intact unfolded protein response pathway

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12 December 2020

A time-dependent phase shift in the mammalian unfolded protein response

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12 December 2020

A role for the unfolded protein response in optimizing antibody secretion

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12 December 2020

Immunoglobulin heavy chain mRNA in mitogen-stimulated B cells

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12 December 2020

The alpha chain of the T cell antigen receptor is degraded in the cytosol

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12 December 2020

Enhanced B-1 cell development, but impaired IgG antibody responses in mice deficient in secreted IgM

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12 December 2020

Identifiers

DOI

10.1084/JEM.20050575

1 reference

14 August 2017

1 reference

14 August 2017

1 reference

PMCID

2212843