Untargeted Plasma Metabolomics Identifies Endogenous Metabolite with Drug-like Properties in Chronic Animal Model of Multiple Sclerosis (Q36407218)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26546682%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

title

Untargeted Plasma Metabolomics Identifies Endogenous Metabolite with Drug-like Properties in Chronic Animal Model of Multiple Sclerosis (English)

1 reference

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29 February 2020

0 references

1 reference

15

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29 February 2020

6

Krzysztof Labuzek

1 reference

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29 February 2020

author name string

Laila M Poisson

1

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29 February 2020

Hamid Suhail

2

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29 February 2020

Jaspreet Singh

3

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29 February 2020

Indrani Datta

4

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29 February 2020

Aleksandar Denic

5

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29 February 2020

Md Nasrul Hoda

7

1 reference

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29 February 2020

Ashray Shankar

8

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29 February 2020

Ashok Kumar

9

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29 February 2020

Mirela Cerghet

10

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29 February 2020

Stanton Elias

11

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29 February 2020

Robert P Mohney

12

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29 February 2020

Moses Rodriguez

13

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29 February 2020

Ramandeep Rattan

14

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29 February 2020

Shailendra Giri

16

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29 February 2020

language of work or name

English

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publication date

6 November 2015

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Journal of Biological Chemistry

29 February 2020

published in

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29 February 2020

volume

290

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29 February 2020

issue

52

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29 February 2020

page(s)

30697-30712

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Dietary Fatty Acids Directly Impact Central Nervous System Autoimmunity via the Small Intestine.

29 February 2020

cites work

1 reference

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Resolvins attenuate inflammation and promote resolution in cigarette smoke-exposed human macrophages

30 September 2017

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Metabolomics for Biomarker Discovery: Moving to the Clinic

30 September 2017

1 reference

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The resolution code of acute inflammation: Novel pro-resolving lipid mediators in resolution

30 September 2017

1 reference

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Effects of n-3 FA supplementation on the release of proresolving lipid mediators by blood mononuclear cells: the OmegAD study

30 September 2017

1 reference

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Regulation of astrocyte activation by glycolipids drives chronic CNS inflammation.

30 September 2017

1 reference

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Protective actions of aspirin-triggered (17R) resolvin D1 and its analogue, 17R-hydroxy-19-para-fluorophenoxy-resolvin D1 methyl ester, in C5a-dependent IgG immune complex-induced inflammation and lung injury

30 September 2017

1 reference

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Pro-resolving lipid mediators are leads for resolution physiology

30 September 2017

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Resolvin D1 promotes the interleukin-4-induced alternative activation in BV-2 microglial cells

30 September 2017

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Proresolving lipid mediators and mechanisms in the resolution of acute inflammation

30 September 2017

1 reference

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Kynurenines in CNS disease: regulation by inflammatory cytokines

30 September 2017

1 reference

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Resolution of inflammation is altered in Alzheimer's disease

30 September 2017

1 reference

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Profile of Circulatory Metabolites in a Relapsing-remitting Animal Model of Multiple Sclerosis using Global Metabolomics

30 September 2017

1 reference

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Resolvins, specialized proresolving lipid mediators, and their potential roles in metabolic diseases

30 September 2017

1 reference

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Disease-modifying therapy in multiple sclerosis and chronic inflammatory demyelinating polyradiculoneuropathy: common and divergent current and future strategies

30 September 2017

1 reference

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Novel n-3 immunoresolvents: structures and actions

30 September 2017

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Recent advances in metabolomics in neurological disease, and future perspectives

30 September 2017

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Association of fish consumption and Ω 3 supplementation with quality of life, disability and disease activity in an international cohort of people with multiple sclerosis

30 September 2017

1 reference

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The kynurenine pathway as a therapeutic target in cognitive and neurodegenerative disorders

30 September 2017

1 reference

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A novel anti-inflammatory and pro-resolving role for resolvin D1 in acute cigarette smoke-induced lung inflammation

30 September 2017

1 reference

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Cerebral biochemical pathways in experimental autoimmune encephalomyelitis and adjuvant arthritis: a comparative metabolomic study

30 September 2017

1 reference

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Potential of urinary metabolites for diagnosing multiple sclerosis

30 September 2017

1 reference

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1α,25-dihydroxyvitamin D3 and resolvin D1 retune the balance between amyloid-β phagocytosis and inflammation in Alzheimer's disease patients

30 September 2017

1 reference

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Resolvin D1 and aspirin-triggered resolvin D1 promote resolution of allergic airways responses.

30 September 2017

1 reference

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Adoptive transfer of immunomodulatory M2 macrophages prevents type 1 diabetes in NOD mice

30 September 2017

1 reference

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Identification of naturally occurring fatty acids of the myelin sheath that resolve neuroinflammation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4692201

First-Line Disease-Modifying Therapies in Paediatric Multiple Sclerosis

30 September 2017

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MetaboAnalyst 2.0--a comprehensive server for metabolomic data analysis

30 September 2017

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Myeloid-derived suppressor cells in transplantation and cancer

30 September 2017

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ω-3 fatty acid treatment in multiple sclerosis (OFAMS Study): a randomized, double-blind, placebo-controlled trial

30 September 2017

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Laquinimod, a quinoline-3-carboxamide, induces type II myeloid cells that modulate central nervous system autoimmunity

30 September 2017

1 reference

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Defects in mitochondrial dynamics and metabolomic signatures of evolving energetic stress in mouse models of familial Alzheimer's disease

30 September 2017

1 reference

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Identification of a new plasma biomarker of Alzheimer's disease using metabolomics technology

30 September 2017

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Challenges and opportunities of metabolomics

30 September 2017

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Protective and pathogenic functions of macrophage subsets

30 September 2017

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Omega-3 fatty acid-derived mediators 17(R)-hydroxy docosahexaenoic acid, aspirin-triggered resolvin D1 and resolvin D2 prevent experimental colitis in mice.

30 September 2017

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n-3 fatty acids in cardiovascular disease

30 September 2017

1 reference

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Repertoire of microglial and macrophage responses after spinal cord injury

30 September 2017

1 reference

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Proteomics-based technologies in the discovery of biomarkers for multiple sclerosis in the cerebrospinal fluid

30 September 2017

1 reference

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The precursor of resolvin D series and aspirin-triggered resolvin D1 display anti-hyperalgesic properties in adjuvant-induced arthritis in rats

30 September 2017

1 reference

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FTY720 (fingolimod) efficacy in an animal model of multiple sclerosis requires astrocyte sphingosine 1-phosphate receptor 1 (S1P1) modulation

30 September 2017

1 reference

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Organization of GC/MS and LC/MS metabolomics data into chemical libraries

30 September 2017

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The role of metabolites and metabolomics in clinically applicable biomarkers of disease.

30 September 2017

1 reference

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Metabolomic profiling in LRRK2-related Parkinson's disease

30 September 2017

1 reference

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Integrated, nontargeted ultrahigh performance liquid chromatography/electrospray ionization tandem mass spectrometry platform for the identification and relative quantification of the small-molecule complement of biological systems

30 September 2017

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Metformin attenuated the autoimmune disease of the central nervous system in animal models of multiple sclerosis

30 September 2017

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Loss of AMPK exacerbates experimental autoimmune encephalomyelitis disease severity

30 September 2017

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MetaboAnalyst: a web server for metabolomic data analysis and interpretation

30 September 2017

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Resolvin D1 controls inflammation initiated by glutathione-lipid conjugates formed during oxidative stress

30 September 2017

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Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression

30 September 2017

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Myeloid-derived suppressor cells as regulators of the immune system

30 September 2017

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Analysis of the adult human plasma metabolome

30 September 2017

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Tumor-infiltrating myeloid-derived suppressor cells are pleiotropic-inflamed monocytes/macrophages that bear M1- and M2-type characteristics

30 September 2017

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Analyzing gene expression data in terms of gene sets: methodological issues

30 September 2017

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Graph-based methods for analysing networks in cell biology

30 September 2017

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A role for docosahexaenoic acid-derived neuroprotectin D1 in neural cell survival and Alzheimer disease

30 September 2017

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The importance of early diagnosis of multiple sclerosis.

30 September 2017

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Prevention of autoimmunity by targeting a distinct, noninvariant CD1d-reactive T cell population reactive to sulfatide

30 September 2017

1 reference

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Resolvins: a family of bioactive products of omega-3 fatty acid transformation circuits initiated by aspirin treatment that counter proinflammation signals

30 September 2017

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Fatty acid composition of phospholipids from platelets and erythrocytes in multiple sclerosis

30 September 2017

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Deficiencies of polyunsaturated fatty acids and replacement by nonessential fatty acids in plasma lipids in multiple sclerosis

30 September 2017

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Protection from endotoxic uveitis by intravitreal Resolvin D1: involvement of lymphocytes, miRNAs, ubiquitin-proteasome, and M1/M2 macrophages

30 September 2017

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Infection regulates pro-resolving mediators that lower antibiotic requirements

28 June 2018

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Metabolomics of cerebrospinal fluid reveals changes in the central nervous system metabolism in a rat model of multiple sclerosis

28 June 2018

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Docosahexaenoic acid prevents dendritic cell maturation, inhibits antigen-specific Th1/Th17 differentiation and suppresses experimental autoimmune encephalomyelitis

28 June 2018

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Studies on the mechanism for renal elimination of N-acetylphenylalanine: its pathophysiologic significance in phenylketonuria

28 June 2018

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Essential fatty acid and lipid profiles in plasma and erythrocytes in patients with multiple sclerosis

28 June 2018

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ω-3 Supplementation increases amyloid-β phagocytosis and resolvin D1 in patients with minor cognitive impairment

28 June 2018

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Pivotal role of choline metabolites in remyelination.

21 September 2018

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n-3 PUFA supplementation benefits microglial responses to myelin pathology.

21 September 2018

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Immunoresolving actions of oral resolvin D1 include selective regulation of the transcription machinery in resolution-phase mouse macrophages.

21 September 2018

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Special lipid-based diets alleviate cognitive deficits in the APPswe/PS1dE9 transgenic mouse model of Alzheimer's disease independent of brain amyloid deposition

21 September 2018

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Resolvin D1 primes the resolution process initiated by calorie restriction in obesity-induced steatohepatitis.

21 September 2018

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Resolvin D1 improves survival in experimental sepsis through reducing bacterial load and preventing excessive activation of inflammatory response

21 September 2018

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LC-MS based serum metabonomic analysis for renal cell carcinoma diagnosis, staging, and biomarker discovery

21 September 2018

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Resolvins as regulators of the immune system.

21 September 2018

1 reference

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Discovery of metabolomics biomarkers for early detection of nephrotoxicity

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4692201

Systems biology: Metabonomics.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4692201

Omega-3 fatty acids and multiple sclerosis: relationship to depression.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4692201

Type II monocytes modulate T cell-mediated central nervous system autoimmune disease

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4692201

Low fat dietary intervention with omega-3 fatty acid supplementation in multiple sclerosis patients.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4692201

Effect of dietary advice and n-3 supplementation in newly diagnosed MS patients.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4692201

CD11b+Ly-6C(hi) suppressive monocytes in experimental autoimmune encephalomyelitis

21 September 2018

1 reference

12 December 2020

Fumaric acid esters are effective in chronic experimental autoimmune encephalomyelitis and suppress macrophage infiltration

1 reference

12 December 2020

Red blood cell and adipose tissue fatty acids in mild inactive multiple sclerosis

1 reference

12 December 2020

Phenotypic and functional profiling of human proinflammatory type-1 and anti-inflammatory type-2 macrophages in response to microbial antigens and IFN-gamma- and CD40L-mediated costimulation

1 reference

12 December 2020

Resolvin D1 and Its Precursor Docosahexaenoic Acid Promote Resolution of Adipose Tissue Inflammation by Eliciting Macrophage Polarization toward an M2-Like Phenotype

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M115.679068

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26546682%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26546682%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

1 reference