Repertoire of microglial and macrophage responses after spinal cord injury (Q37889633)

24 August 2017

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title

Repertoire of microglial and macrophage responses after spinal cord injury (English)

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24 August 2017

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Samuel David

1

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PubMed ID

21673720

24 August 2017

Antje Kroner

series ordinal

2

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PubMed ID

21673720

24 August 2017

language of work or name

English

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publication date

15 June 2011

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Nature Reviews Neuroscience

24 August 2017

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24 August 2017

12

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24 August 2017

7

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24 August 2017

388-399

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https://scigraph.springernature.com/pub.10.1038/nrn3053

24 August 2017

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Dendritic cells permit immune invasion of the CNS in an animal model of multiple sclerosis.

31 March 2020

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Circulating Ly-6C+ myeloid precursors migrate to the CNS and play a pathogenic role during autoimmune demyelinating disease.

31 March 2020

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Astrocytes initiate inflammation in the injured mouse spinal cord by promoting the entry of neutrophils and inflammatory monocytes in an IL-1 receptor/MyD88-dependent fashion

31 March 2020

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Rats and mice exhibit distinct inflammatory reactions after spinal cord injury

31 March 2020

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Inflammation and its role in neuroprotection, axonal regeneration and functional recovery after spinal cord injury

31 March 2020

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The cellular inflammatory response in human spinal cords after injury.

31 March 2020

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Lipoxins and new lipid mediators in the resolution of inflammation

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Resolvin E1 and protectin D1 activate inflammation-resolution programmes

31 March 2020

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Non-resolving aspects of acute inflammation after spinal cord injury (SCI): indices and resolution plateau.

31 March 2020

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A combination of intravenous and dietary docosahexaenoic acid significantly improves outcome after spinal cord injury

31 March 2020

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Omega-3 fatty acids improve recovery, whereas omega-6 fatty acids worsen outcome, after spinal cord injury in the adult rat

31 March 2020

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Docosahexaenoic acid prevents white matter damage after spinal cord injury.

31 March 2020

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The acute administration of eicosapentaenoic acid is neuroprotective after spinal cord compression injury in rats

31 March 2020

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Fenretinide promotes functional recovery and tissue protection after spinal cord contusion injury in mice.

31 March 2020

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Gr-1+CD115+ Immature Myeloid Suppressor Cells Mediate the Development of Tumor-Induced T Regulatory Cells and T-Cell Anergy in Tumor-Bearing Host

31 March 2020

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Normal human monocytes exposed to glioma cells acquire myeloid-derived suppressor cell-like properties.

31 March 2020

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Subpopulations of mouse blood monocytes differ in maturation stage and inflammatory response.

31 March 2020

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Monitoring of blood vessels and tissues by a population of monocytes with patrolling behavior

31 March 2020

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31 March 2020

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The healing myocardium sequentially mobilizes two monocyte subsets with divergent and complementary functions

31 March 2020

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31 March 2020

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M2b monocytes predominated in peripheral blood of severely burned patients

31 March 2020

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Neuroprotection and progenitor cell renewal in the injured adult murine retina requires healing monocyte-derived macrophages.

31 March 2020

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Infiltrating blood-derived macrophages are vital cells playing an anti-inflammatory role in recovery from spinal cord injury in mice

31 March 2020

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ATP mediates rapid microglial response to local brain injury in vivo

31 March 2020

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Microglia processes block the spread of damage in the brain and require functional chloride channels

31 March 2020

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The P2Y12 receptor regulates microglial activation by extracellular nucleotides

31 March 2020

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ATP-induced chemotaxis of microglial processes requires P2Y receptor-activated initiation of outward potassium currents.

31 March 2020

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P2 receptor-mediated stimulation of the PI3-K/Akt-pathway in vivo

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Akt activation is involved in P2Y12 receptor-mediated chemotaxis of microglia

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Regulation of dynamic behavior of retinal microglia by CX3CR1 signaling

31 March 2020

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NO mediates microglial response to acute spinal cord injury under ATP control in vivo

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Expression of CCR2 in Both Resident and Bone Marrow-Derived Microglia Plays a Critical Role in Neuropathic Pain

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Monocyte chemoattractant protein-1 (MCP-1) produced via NF-kappaB signaling pathway mediates migration of amoeboid microglia in the periventricular white matter in hypoxic neonatal rats.

31 March 2020

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AIF-1 expression defines a proliferating and alert microglial/macrophage phenotype following spinal cord injury in rats

31 March 2020

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Origin of CD11b+ macrophage-like cells in the CNS of PLP-overexpressing mice: low influx of haematogenous macrophages and unchanged blood-brain-barrier in the optic nerve.

31 March 2020

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Immune cells contribute to myelin degeneration and axonopathic changes in mice overexpressing proteolipid protein in oligodendrocytes

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Sialoadhesin deficiency ameliorates myelin degeneration and axonopathic changes in the CNS of PLP overexpressing mice.

31 March 2020

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Identification of glial cell proliferation in early multiple sclerosis lesions.

31 March 2020

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Presence of labeled monocytes, macrophages and microglia in a stab wound of the brain following an injection of bone marrow cells labeled with3H-uridine into rats

31 March 2020

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Bone marrow chimeric rats reveal the unique distribution of resident and recruited macrophages in the contused rat spinal cord.

31 March 2020

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Depletion of hematogenous macrophages promotes partial hindlimb recovery and neuroanatomical repair after experimental spinal cord injury

31 March 2020

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Caught in the act: in vivo mapping of macrophage infiltration in nerve injury by magnetic resonance imaging.

31 March 2020

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Fate of endogenous stem/progenitor cells following spinal cord injury

31 March 2020

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Delayed accumulation of activated macrophages and inhibition of remyelination after spinal cord injury in an adult rodent model.

31 March 2020

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Proinflammatory cytokine synthesis in the injured mouse spinal cord: multiphasic expression pattern and identification of the cell types involved.

31 March 2020

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Early expression and cellular localization of proinflammatory cytokines interleukin-1beta, interleukin-6, and tumor necrosis factor-alpha in human traumatic spinal cord injury.

31 March 2020

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IL-1 receptor antagonist prevents apoptosis and caspase-3 activation after spinal cord injury.

31 March 2020

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Severity-dependent expression of pro-inflammatory cytokines in traumatic spinal cord injury in the rat

31 March 2020

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Cell death after spinal cord injury is exacerbated by rapid TNF alpha-induced trafficking of GluR2-lacking AMPARs to the plasma membrane

31 March 2020

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TNFR1 signalling is critical for the development of demyelination and the limitation of T-cell responses during immune-mediated CNS disease

31 March 2020

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CD95-ligand on peripheral myeloid cells activates Syk kinase to trigger their recruitment to the inflammatory site.

31 March 2020

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FK 506 reduces tissue damage and prevents functional deficit after spinal cord injury in the rat.

31 March 2020

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Minocycline treatment reduces delayed oligodendrocyte death, attenuates axonal dieback, and improves functional outcome after spinal cord injury.

31 March 2020

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A combination immunomodulatory treatment promotes neuroprotection and locomotor recovery after contusion SCI.

31 March 2020

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Distinct role of MAPKAPK-2 in the regulation of TNF gene expression by Toll-like receptor 7 and 9 ligands

31 March 2020

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The Ca2+-activated K+ channel KCNN4/KCa3.1 contributes to microglia activation and nitric oxide-dependent neurodegeneration.

31 March 2020

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Mechanisms of microglia-mediated neurotoxicity in a new model of the stroke penumbra.

31 March 2020

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Temporal and segmental distribution of constitutive and inducible nitric oxide synthases after traumatic spinal cord injury: effect of aminoguanidine treatment

31 March 2020

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Increased expression of cyclo-oxygenase 2 and vascular endothelial growth factor in lesioned spinal cord by transplanted olfactory ensheathing cells.

31 March 2020

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Comparison of iNOS inhibition by antisense and pharmacological inhibitors after spinal cord injury

31 March 2020

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Control of microglial neurotoxicity by the fractalkine receptor

31 March 2020

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Role of CX3CR1 (fractalkine receptor) in brain damage and inflammation induced by focal cerebral ischemia in mouse.

31 March 2020

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Mice deficient in fractalkine are less susceptible to cerebral ischemia-reperfusion injury.

31 March 2020

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CX3CR1 deficiency alters microglial activation and reduces beta-amyloid deposition in two Alzheimer's disease mouse models.

31 March 2020

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TNF alpha promotes proliferation of oligodendrocyte progenitors and remyelination.

31 March 2020

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Clearance of apoptotic neurons without inflammation by microglial triggering receptor expressed on myeloid cells-2.

31 March 2020

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A role for Nogo receptor in macrophage clearance from injured peripheral nerve

31 March 2020

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Nogo-A and nogo receptor expression in demyelinating lesions of multiple sclerosis.

31 March 2020

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Novel roles for Nogo receptor in inflammation and disease.

31 March 2020

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Molecular mechanisms responsible for microglia-derived protection of Sprague-Dawley rat brain cells during in vitro ischemia

31 March 2020

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Expression of transforming growth factor-beta 1 and interleukin-1 beta mRNA in rat brain following transient forebrain ischemia.

31 March 2020

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Microglia overexpressing the macrophage colony-stimulating factor receptor are neuroprotective in a microglial-hippocampal organotypic coculture system

31 March 2020

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Dendritic cell differentiation signals induce anti-inflammatory properties in human adult microglia.

31 March 2020

1 reference

Delayed GM-CSF treatment stimulates axonal regeneration and functional recovery in paraplegic rats via an increased BDNF expression by endogenous macrophages.

31 March 2020

1 reference

Role of granulocyte-macrophage colony-stimulating factor in preventing apoptosis and improving functional outcome in experimental spinal cord contusion injury.

31 March 2020

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Implantation of stimulated homologous macrophages results in partial recovery of paraplegic rats.

31 March 2020

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Potential repair of rat spinal cord injuries using stimulated homologous macrophages

31 March 2020

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Transplantation of activated macrophages overcomes central nervous system regrowth failure

31 March 2020

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Peripheral nerve-stimulated macrophages simulate a peripheral nerve-like regenerative response in rat transected optic nerve.

31 March 2020

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Lens injury stimulates axon regeneration in the mature rat optic nerve

31 March 2020

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Macrophage-derived factors stimulate optic nerve regeneration.

31 March 2020

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Oncomodulin is a macrophage-derived signal for axon regeneration in retinal ganglion cells

31 March 2020

1 reference

Interleukin-4 and interferon-gamma: the quintessence of a mutual antagonistic relationship

31 March 2020

1 reference

Interleukin 4 suppresses interleukin 2 and interferon gamma production by naive T cells stimulated by accessory cell-dependent receptor engagement

31 March 2020

1 reference

31 March 2020

IL-13 effector functions

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Fibrotic disease and the T(H)1/T(H)2 paradigm

31 March 2020

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Monocyte and macrophage heterogeneity

31 March 2020

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Alternative activation of macrophages: an immunologic functional perspective

31 March 2020

1 reference

Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm

31 March 2020

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Orchestration of macrophage polarization

31 March 2020

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Macrophage polarization in tumour progression

31 March 2020

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Characterization and modeling of monocyte-derived macrophages after spinal cord injury

31 March 2020

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Identification of two distinct macrophage subsets with divergent effects causing either neurotoxicity or regeneration in the injured mouse spinal cord

31 March 2020

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Beneficial effects of secretory leukocyte protease inhibitor after spinal cord injury

31 March 2020

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Mitogen-activated protein kinase-activated protein kinase 2 (MK2) contributes to secondary damage after spinal cord injury.

31 March 2020

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The protective effects of 15-deoxy-delta-(12,14)-prostaglandin J2 in spinal cord injury

31 March 2020

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Expression and detrimental role of hematopoietic prostaglandin D synthase in spinal cord contusion injury

31 March 2020

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Deletion of macrophage migration inhibitory factor attenuates neuronal death and promotes functional recovery after compression-induced spinal cord injury in mice

31 March 2020

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Increased oxidative activity in human blood neutrophils and monocytes after spinal cord injury

31 March 2020

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Early anti-inflammatory treatment reduces lipid peroxidation and protein nitration after spinal cord injury in rats.

31 March 2020

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Ceruloplasmin protects injured spinal cord from iron-mediated oxidative damage.

31 March 2020

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Altered M1/M2 activation patterns of monocytes in severe relapsing experimental rat model of multiple sclerosis. Amelioration of clinical status by M2 activated monocyte administration.

31 March 2020

1 reference

Differential expression of SOCS1 in macrophages in relapsing-remitting and chronic EAE and its role in disease severity

31 March 2020

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Transcriptional profiling of the human monocyte-to-macrophage differentiation and polarization: new molecules and patterns of gene expression

31 March 2020

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Chondroitinase ABC promotes functional recovery after spinal cord injury

31 March 2020

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The role of extracellular matrix in CNS regeneration

31 March 2020

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The role of chondroitin sulfate proteoglycans in regeneration and plasticity in the central nervous system

31 March 2020

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Regeneration of CNS axons back to their target following treatment of adult rat brain with chondroitinase ABC.

31 March 2020

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Overcoming macrophage-mediated axonal dieback following CNS injury

31 March 2020

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Another barrier to regeneration in the CNS: activated macrophages induce extensive retraction of dystrophic axons through direct physical interactions

31 March 2020

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RGMa inhibition promotes axonal growth and recovery after spinal cord injury.

31 March 2020

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Spinal cord injury-induced lesional expression of the repulsive guidance molecule (RGM).

31 March 2020

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Myelin-laden macrophages are anti-inflammatory, consistent with foam cells in multiple sclerosis.

31 March 2020

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Myelin-phagocytosing macrophages in isolated sciatic and optic nerves reveal a unique reactive phenotype

31 March 2020

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CNS-derived interleukin-4 is essential for the regulation of autoimmune inflammation and induces a state of alternative activation in microglial cells

31 March 2020

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Alternatively activated alveolar macrophages in pulmonary fibrosis-mediator production and intracellular signal transduction

31 March 2020

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Markers of macrophage differentiation in experimental silicosis

31 March 2020

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Identification of alternatively activated macrophages in new-onset paediatric and adult immunoglobulin A nephropathy: potential role in mesangial matrix expansion

31 March 2020

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Alternative activation of macrophages in human peritoneum: implications for peritoneal fibrosis

31 March 2020

1 reference

Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes

31 March 2020

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Activation of a TGF-beta-specific multistep gene expression program in mature macrophages requires glucocorticoid-mediated surface expression of TGF-beta receptor II

31 March 2020

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Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization

31 March 2020

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An unrestrained proinflammatory M1 macrophage population induced by iron impairs wound healing in humans and mice

31 March 2020

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The interaction of human natural killer cells with either unpolarized or polarized macrophages results in different functional outcomes

31 March 2020

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Differential regulation of chemokine production by Fcgamma receptor engagement in human monocytes: association of CCL1 with a distinct form of M2 monocyte activation (M2b, Type 2).

31 March 2020

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Heterogeneity of human blood monocytes: the CD14+ CD16+ subpopulation

31 March 2020

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Microglia in the adult brain arise from Ly-6ChiCCR2+ monocytes only under defined host conditions

31 March 2020

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The chemokine system in diverse forms of macrophage activation and polarization

31 March 2020

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Macrophage activation and polarization

31 March 2020

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Interleukin 4 potently enhances murine macrophage mannose receptor activity: a marker of alternative immunologic macrophage activation

31 March 2020

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Alternatively activated macrophages differentially express fibronectin and its splice variants and the extracellular matrix protein betaIG-H3.

31 March 2020

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Differential regulation of nitric oxide synthase-2 and arginase-1 by type 1/type 2 cytokines in vivo: granulomatous pathology is shaped by the pattern of L-arginine metabolism

31 March 2020

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Alternative activation of macrophages

31 March 2020

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Arginase-1 and Ym1 are markers for murine, but not human, alternatively activated myeloid cells

31 March 2020

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Transcriptional profiling reveals complex regulation of the monocyte IL-1 beta system by IL-13.

31 March 2020

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Shifts in macrophage phenotypes and macrophage competition for arginine metabolism affect the severity of muscle pathology in muscular dystrophy

31 March 2020

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Other functions, other genes: alternative activation of antigen-presenting cells

31 March 2020

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Cutting edge: biasing immune responses by directing antigen to macrophage Fc gamma receptors.

31 March 2020

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The many faces of macrophage activation

31 March 2020

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Proinflammatory clearance of apoptotic neutrophils induces an IL-12(low)IL-10(high) regulatory phenotype in macrophages

31 March 2020

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Activation of lung macrophage subpopulations in experimental acute pancreatitis.

31 March 2020

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Nuclear receptor signaling in macrophages.

31 March 2020

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Glucocorticoids induce differentiation of a specifically activated, anti-inflammatory subtype of human monocytes.

31 March 2020

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A novel phenotype for an activated macrophage: the type 2 activated macrophage.

31 March 2020

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12 December 2020

Contrasting mechanisms for suppression of macrophage cytokine release by transforming growth factor-beta and interleukin-10.

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12 December 2020

TNF-alpha blockage in a mouse model of SCI: evidence for improved outcome

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12 December 2020

IL-4 inhibits the expression of IL-8 from stimulated human monocytes

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12 December 2020

Hepcidin--a peptide hormone at the interface of innate immunity and iron metabolism.

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12 December 2020

P2Y12 receptor-mediated integrin-beta1 activation regulates microglial process extension induced by ATP

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12 December 2020

Identifiers

DOI

10.1038/NRN3053

1 reference

24 August 2017

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PubMed ID

21673720