Analysis of a wild mouse promoter variant reveals a novel role for FcγRIIb in the control of the germinal center and autoimmunity. (Q36409027)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23109709%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

title

Analysis of a wild mouse promoter variant reveals a novel role for FcγRIIb in the control of the germinal center and autoimmunity (English)

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16 February 2020

1

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16 February 2020

Kate E. Lawlor

4

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16 February 2020

Antony J Cutler

5

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16 February 2020

K G Smith

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2

Menna R Clatworthy

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16 February 2020

7

Paul A Lyons

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16 February 2020

author name string

Susanne Bökers

3

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16 February 2020

Frank Köntgen

6

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16 February 2020

language of work or name

English

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publication date

29 October 2012

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Journal of Experimental Medicine

16 February 2020

published in

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16 February 2020

volume

209

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16 February 2020

issue

12

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16 February 2020

page(s)

2307-2319

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B cell receptor signal transduction in the GC is short-circuited by high phosphatase activity

16 February 2020

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FcgammaRIIB Ile232Thr transmembrane polymorphism associated with human systemic lupus erythematosus decreases affinity to lipid rafts and attenuates inhibitory effects on B cell receptor signaling.

30 September 2017

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28 June 2018

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A promoter haplotype of the immunoreceptor tyrosine-based inhibitory motif-bearing FcgammaRIIb alters receptor expression and associates with autoimmunity. I. Regulatory FCGR2B polymorphisms and their association with systemic lupus erythematosus

21 September 2018

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21 September 2018

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21 September 2018

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21 September 2018

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21 September 2018

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21 October 2018

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Crossref

https://api.crossref.org/works/10.1084%2FJEM.20121752

Polymorphisms in IgG Fc receptor IIB regulatory regions associated with autoimmune susceptibility

21 January 2018

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12 December 2020

Spontaneous autoimmune disease in Fc(gamma)RIIB-deficient mice results from strain-specific epistasis

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12 December 2020

Fcgamma receptor gene polymorphisms in Japanese patients with systemic lupus erythematosus: contribution of FCGR2B to genetic susceptibility

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12 December 2020

Mycobacteria-induced autoantibody production is associated with susceptibility to infection but not with host propensity to develop autoimmune disease

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12 December 2020

Control of multiple autoantibodies linked with a lupus nephritis susceptibility locus in New Zealand black mice

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12 December 2020

Restoration of tolerance in lupus by targeted inhibitory receptor expression

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12 December 2020

Decreased transcription of the human FCGR2B gene mediated by the -343 G/C promoter polymorphism and association with systemic lupus erythematosus

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12 December 2020

Failed up-regulation of the inhibitory IgG Fc receptor Fc gamma RIIB on germinal center B cells in autoimmune-prone mice is not associated with deletion polymorphisms in the promoter region of the Fc gamma RIIB gene

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12 December 2020

FcγRIIb controls bone marrow plasma cell persistence and apoptosis

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12 December 2020

Expression of the autoimmune Fcgr2b NZW allele fails to be upregulated in germinal center B cells and is associated with increased IgG production

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12 December 2020

Engineering the mouse genome to model human disease for drug discovery

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12 December 2020

The inhibiting Fc receptor for IgG, FcγRIIB, is a modifier of autoimmune susceptibility

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12 December 2020

Autoimmune-prone mice share a promoter haplotype associated with reduced expression and function of the Fc receptor FcgammaRII

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12 December 2020

Hypergammaglobulinemia and autoantibody induction mechanisms in viral infections

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12 December 2020

The need for central and peripheral tolerance in the B cell repertoire

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12 December 2020

Identifiers

DOI

10.1084/JEM.20121752

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23109709%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23109709%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23109709%20AND%20SRC:MED&resulttype=core&format=json