Activation of microRNA-494-targeting Bmi1 and ADAM10 by silibinin ablates cancer stemness and predicts favourable prognostic value in head and neck squamous cell carcinomas (Q36414361)

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English	Activation of microRNA-494-targeting Bmi1 and ADAM10 by silibinin ablates cancer stemness and predicts favourable prognostic value in head and neck squamous cell carcinomas	scientific article

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scholarly article

1 reference

Europe PubMed Central

14 August 2017

Activation of microRNA-494-targeting Bmi1 and ADAM10 by silibinin ablates cancer stemness and predicts favourable prognostic value in head and neck squamous cell carcinomas (English)

1 reference

Europe PubMed Central

14 August 2017

1 reference

based on heuristic

inferred from title

author name string

Yu-Chao Chang

1

1 reference

Europe PubMed Central

14 August 2017

Chia-Ing Jan

2

1 reference

Europe PubMed Central

14 August 2017

Chih-Yu Peng

3

1 reference

Europe PubMed Central

14 August 2017

Yu-Chi Lai

4

1 reference

Europe PubMed Central

14 August 2017

Fang-Wei Hu

5

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Europe PubMed Central

14 August 2017

Cheng-Chia Yu

6

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Europe PubMed Central

14 August 2017

language of work or name

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publication date

8 June 2015

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Europe PubMed Central

14 August 2017

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Europe PubMed Central

14 August 2017

6

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Europe PubMed Central

14 August 2017

24002-24016

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Europe PubMed Central

14 August 2017

27

1 reference

Europe PubMed Central

14 August 2017

The microRNA-200 family: small molecules with novel roles in cancer development, progression and therapy

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Overexpression of secretagogin inhibits cell apoptosis and induces chemoresistance in small cell lung cancer under the regulation of miR-494

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4695166

30 September 2017

ADAM10 regulates Notch function in intestinal stem cells of mice

1 reference

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Silibinin strongly inhibits the growth kinetics of colon cancer stem cell-enriched spheroids by modulating interleukin 4/6-mediated survival signals

1 reference

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30 September 2017

Down-regulation of microRNA-494 via loss of SMAD4 increases FOXM1 and β-catenin signaling in pancreatic ductal adenocarcinoma cells

1 reference

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30 September 2017

The role of BMI1 as a biomarker of cancer stem cells in head and neck cancer: a review

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4695166

30 September 2017

MicroRNA-494-3p targets CXCR4 to suppress the proliferation, invasion, and migration of prostate cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4695166

30 September 2017

Cancer statistics, 2014

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4695166

30 September 2017

Silybin-mediated inhibition of Notch signaling exerts antitumor activity in human hepatocellular carcinoma cells

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A disintegrin and metalloproteinases 10 and 17 modulate the immunogenicity of glioblastoma-initiating cells

1 reference

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30 September 2017

Ionizing radiation-inducible miR-494 promotes glioma cell invasion through EGFR stabilization by targeting p190B rhoGAP.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4695166

30 September 2017

ADAM 10 is over expressed in oral squamous cell carcinoma and contributes to invasive behaviour through a functional association with αvβ6 integrin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4695166

30 September 2017

Silibinin inhibits β-catenin/ZEB1 signaling and suppresses bladder cancer metastasis via dual-blocking epithelial-mesenchymal transition and stemness

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4695166

30 September 2017

Silibinin suppresses EMT-driven erlotinib resistance by reversing the high miR-21/low miR-200c signature in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4695166

30 September 2017

miR145 targets the SOX9/ADAM17 axis to inhibit tumor-initiating cells and IL-6-mediated paracrine effects in head and neck cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4695166

30 September 2017

MicroRNAs regulate both epithelial-to-mesenchymal transition and cancer stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4695166

30 September 2017

MiR-494 is regulated by ERK1/2 and modulates TRAIL-induced apoptosis in non-small-cell lung cancer through BIM down-regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4695166

30 September 2017

Silibinin inhibits Wnt/β-catenin signaling by suppressing Wnt co-receptor LRP6 expression in human prostate and breast cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4695166

30 September 2017

Coordinated effects of microRNA-494 induce G₂/M arrest in human cholangiocarcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4695166

30 September 2017

Cancer stem cells: current status and evolving complexities

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4695166

30 September 2017

Nonadhesive culture system as a model of rapid sphere formation with cancer stem cell properties

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4695166

30 September 2017

CD133/Src axis mediates tumor initiating property and epithelial-mesenchymal transition of head and neck cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4695166

30 September 2017

MicroRNA-494 downregulates KIT and inhibits gastrointestinal stromal tumor cell proliferation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4695166

30 September 2017

MicroRNA regulation of cancer stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4695166

30 September 2017

Silibinin inhibits the invasion and migration of renal carcinoma 786-O cells in vitro, inhibits the growth of xenografts in vivo and enhances chemosensitivity to 5-fluorouracil and paclitaxel

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4695166

30 September 2017

TGFbeta/TNF(alpha)-mediated epithelial-mesenchymal transition generates breast cancer stem cells with a claudin-low phenotype

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4695166

30 September 2017

The microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4695166

30 September 2017

Chemopreventive and chemotherapeutic effects of intravesical silibinin against bladder cancer by acting on mitochondria

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4695166

30 September 2017

Glioblastoma stem-like cells give rise to tumour endothelium.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4695166

30 September 2017

Bmi-1 Regulates Snail Expression and Promotes Metastasis Ability in Head and Neck Squamous Cancer-Derived ALDH1 Positive Cells

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30 September 2017

miR-200a regulates epithelial-mesenchymal to stem-like transition via ZEB2 and beta-catenin signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4695166

30 September 2017

Stem-like ovarian cancer cells can serve as tumor vascular progenitors

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4695166

30 September 2017

MiR-21 is an EGFR-regulated anti-apoptotic factor in lung cancer in never-smokers

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4695166

30 September 2017

The increasing complexity of the cancer stem cell paradigm

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4695166

30 September 2017

Aldehyde dehydrogenase 1 is a putative marker for cancer stem cells in head and neck squamous cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4695166

30 September 2017

Silibinin suppresses growth of human prostate carcinoma PC-3 orthotopic xenograft via activation of extracellular signal-regulated kinase 1/2 and inhibition of signal transducers and activators of transcription signaling

1 reference

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30 September 2017

MicroRNA profiling as a tool to understand prognosis, therapy response and resistance in breast cancer.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4695166

30 September 2017

The ADAMs: signalling scissors in the tumour microenvironment

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30 September 2017

Positive correlations of Oct-4 and Nanog in oral cancer stem-like cells and high-grade oral squamous cell carcinoma

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30 September 2017

The epithelial-mesenchymal transition generates cells with properties of stem cells

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4695166

30 September 2017

Identification of human aldehyde dehydrogenase 1 family member A1 as a novel CD8+ T-cell-defined tumor antigen in squamous cell carcinoma of the head and neck

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4695166

30 September 2017

MicroRNA sponges: competitive inhibitors of small RNAs in mammalian cells

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4695166

30 September 2017

Identification of a subpopulation of cells with cancer stem cell properties in head and neck squamous cell carcinoma

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30 September 2017

Reassessment of the role of induction chemotherapy for head and neck cancer

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Patterns of cancer incidence, mortality, and prevalence across five continents: defining priorities to reduce cancer disparities in different geographic regions of the world

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4695166

30 September 2017

Silibinin inhibits invasion of oral cancer cells by suppressing the MAPK pathway

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30 September 2017

Tumour stem cells and drug resistance

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Polycombing the genome: PcG, trxG, and chromatin silencing

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Impairment of tumor-initiating stem-like property and reversal of epithelial-mesenchymal transdifferentiation in head and neck cancer by resveratrol treatment

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28 June 2018

MicroRNA-200c attenuates tumour growth and metastasis of presumptive head and neck squamous cell carcinoma stem cells.

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MicroRNA signature predicts survival and relapse in lung cancer.

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21 September 2018

miR‑494 is an independent prognostic factor and promotes cell migration and invasion in colorectal cancer by directly targeting PTEN

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https://pubmed.ncbi.nlm.nih.gov/26090866

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cancer stem cells: an evolving concept

1 reference

https://pubmed.ncbi.nlm.nih.gov/26090866

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cancer stem cells: the challenges ahead

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https://pubmed.ncbi.nlm.nih.gov/26090866

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based on heuristic

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Quantitative evaluation of human gingival epithelial cell attachment to implant surfaces in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/26090866

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based on heuristic

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Identifiers

10.18632/ONCOTARGET.4365

0 references

1 reference

Europe PubMed Central

14 August 2017

1 reference

Europe PubMed Central

14 August 2017

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