Melanoma Cell-Intrinsic PD-1 Receptor Functions Promote Tumor Growth (Q36429062)

14 August 2017

Melanoma Cell-Intrinsic PD-1 Receptor Functions Promote Tumor Growth (English)

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14 August 2017

2

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2 June 2020

Emmanuella Guenova

6

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2 June 2020

Markus H. Frank

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2 June 2020

Tobias Schatton

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13

Wolfram Hoetzenecker

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15

Reinhard Dummer

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2 June 2020

author name string

Sonja Kleffel

1

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2 June 2020

Steven R Barthel

3

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2 June 2020

Hansgeorg Mueller

4

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2 June 2020

Christoph Schlapbach

5

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2 June 2020

Christopher P Elco

7

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2 June 2020

Nayoung Lee

8

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2 June 2020

Vikram R Juneja

9

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2 June 2020

Qian Zhan

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2 June 2020

Christine G Lian

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2 June 2020

Rahel Thomi

12

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2 June 2020

Antonio Cozzio

14

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2 June 2020

Martin C Mihm

16

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2 June 2020

George F Murphy

19

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2 June 2020

Arlene H Sharpe

20

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2 June 2020

Thomas S Kupper

21

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2 June 2020

Keith T Flaherty

17

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2 June 2020

language of work or name

English

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publication date

1 September 2015

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14 August 2017

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2 June 2020

volume

162

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2 June 2020

issue

6

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2 June 2020

page(s)

1242-1256

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Nivolumab versus chemotherapy in patients with advanced melanoma who progressed after anti-CTLA-4 treatment (CheckMate 037): a randomised, controlled, open-label, phase 3 trial.

2 June 2020

cites work

1 reference

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Cancer immunology. Mutational landscape determines sensitivity to PD-1 blockade in non-small cell lung cancer

30 September 2017

1 reference

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Immune Checkpoint Blockade in Cancer Therapy

30 September 2017

1 reference

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Checkpoint blockade cancer immunotherapy targets tumour-specific mutant antigens

30 September 2017

1 reference

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Predicting immunogenic tumour mutations by combining mass spectrometry and exome sequencing.

30 September 2017

1 reference

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PD-1 blockade induces responses by inhibiting adaptive immune resistance

30 September 2017

1 reference

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Predictive correlates of response to the anti-PD-L1 antibody MPDL3280A in cancer patients

30 September 2017

1 reference

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Genetic basis for clinical response to CTLA-4 blockade in melanoma

30 September 2017

1 reference

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TORC1 suppression predicts responsiveness to RAF and MEK inhibition in BRAF-mutant melanoma

30 September 2017

1 reference

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Nivolumab plus ipilimumab in advanced melanoma

30 September 2017

1 reference

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Safety and Tumor Responses with Lambrolizumab (Anti–PD-1) in Melanoma

30 September 2017

1 reference

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Combined targeting of MEK and PI3K/mTOR effector pathways is necessary to effectively inhibit NRAS mutant melanoma in vitro and in vivo

30 September 2017

1 reference

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The activation of MAPK in melanoma cells resistant to BRAF inhibition promotes PD-L1 expression that is reversible by MEK and PI3K inhibition

30 September 2017

1 reference

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PD-1 blockade enhances T-cell migration to tumors by elevating IFN-γ inducible chemokines

30 September 2017

1 reference

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Safety, activity, and immune correlates of anti-PD-1 antibody in cancer

30 September 2017

1 reference

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From genes to drugs: targeted strategies for melanoma

30 September 2017

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The blockade of immune checkpoints in cancer immunotherapy

30 September 2017

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Tyrosine phosphatase SHP2 promotes breast cancer progression and maintains tumor-initiating cells via activation of key transcription factors and a positive feedback signaling loop

30 September 2017

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Targeting the PD-1/B7-H1(PD-L1) pathway to activate anti-tumor immunity

30 September 2017

1 reference

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Immune inhibitory molecules LAG-3 and PD-1 synergistically regulate T-cell function to promote tumoral immune escape

30 September 2017

1 reference

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Human CD271-positive melanoma stem cells associated with metastasis establish tumor heterogeneity and long-term growth

30 September 2017

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Targeting Tim-3 and PD-1 pathways to reverse T cell exhaustion and restore anti-tumor immunity

30 September 2017

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Upregulation of Tim-3 and PD-1 expression is associated with tumor antigen–specific CD8+ T cell dysfunction in melanoma patients

30 September 2017

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Modulation of T-cell activation by malignant melanoma initiating cells

30 September 2017

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PD-L1 regulates the development, maintenance, and function of induced regulatory T cells

30 September 2017

1 reference

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PD-1 signaling in primary T cells

30 September 2017

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Identification of cells initiating human melanomas

30 September 2017

1 reference

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Protein-tyrosine phosphatases and cancer

30 September 2017

1 reference

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Tumor-associated B7-H1 promotes T-cell apoptosis: a potential mechanism of immune evasion

30 September 2017

1 reference

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SHP-2/PTPN11 mediates gliomagenesis driven by PDGFRA and INK4A/ARF aberrations in mice and humans

30 September 2017

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10.1016/J.CELL.2015.08.052

28 June 2018

Identifiers

DOI

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2 June 2020

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2 June 2020

PubMed publication ID

26359984

1 reference