From genes to drugs: targeted strategies for melanoma (Q37999967)

26 August 2017

From genes to drugs: targeted strategies for melanoma (English)

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Author Correction: From genes to drugs: targeted strategies for melanoma

26 August 2017

corrigendum / erratum

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1

Keith T Flaherty

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26 August 2017

3

David E Fisher

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26 August 2017

2

F Stephen Hodi

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26 August 2017

language of work or name

English

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publication date

5 April 2012

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26 August 2017

Nature Reviews Cancer

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26 August 2017

12

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26 August 2017

5

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26 August 2017

349-361

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https://scigraph.springernature.com/pub.10.1038/nrc3218

26 August 2017

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31 March 2020

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Identification of the immunodominant peptides of the MART-1 human melanoma antigen recognized by the majority of HLA-A2-restricted tumor infiltrating lymphocytes

31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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Review: dendritic cell-based vaccine in the treatment of patients with advanced melanoma

31 March 2020

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Dendritic cells: a journey from laboratory to clinic

31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting anti-tumor immunity

31 March 2020

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Role of bone marrow-derived cells in presenting MHC class I-restricted tumor antigens

31 March 2020

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The central role of CD4(+) T cells in the antitumor immune response

31 March 2020

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Vaccination with irradiated autologous melanoma cells engineered to secrete human granulocyte-macrophage colony-stimulating factor generates potent antitumor immunity in patients with metastatic melanoma

31 March 2020

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Vaccination with irradiated, autologous melanoma cells engineered to secrete granulocyte-macrophage colony-stimulating factor by adenoviral-mediated gene transfer augments antitumor immunity in patients with metastatic melanoma.

31 March 2020

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Lymphoproliferation in CTLA-4-deficient mice is mediated by costimulation-dependent activation of CD4+ T cells

31 March 2020

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Enhancement of antitumor immunity by CTLA-4 blockade

31 March 2020

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31 March 2020

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Cancer regression and autoimmunity induced by cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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CTLA-4: negative regulator of the immune response and a target for cancer therapy

31 March 2020

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Improved Survival with Ipilimumab in Patients with Metastatic Melanoma

31 March 2020

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Ipilimumab plus dacarbazine for previously untreated metastatic melanoma

31 March 2020

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Involvement of PD-L1 on tumor cells in the escape from host immune system and tumor immunotherapy by PD-L1 blockade

31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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Inhibition of myeloid cell differentiation in cancer: the role of reactive oxygen species

31 March 2020

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31 March 2020

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New insights into the role of 4-1BB in immune responses: beyond CD8+ T cells

31 March 2020

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Immune responses in 4-1BB (CD137)-deficient mice

31 March 2020

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DCs and CD40-activated B cells: current and future avenues to cellular cancer immunotherapy

31 March 2020

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Clinical activity and immune modulation in cancer patients treated with CP-870,893, a novel CD40 agonist monoclonal antibody.

31 March 2020

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A translational bridge to cancer immunotherapy: exploiting costimulation and target antigens for active and passive T cell immunotherapy

31 March 2020

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Enhancing the immunostimulatory function of dendritic cells by transfection with mRNA encoding OX40 ligand.

31 March 2020

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Somatic activation of KIT in distinct subtypes of melanoma

31 March 2020

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Analysis of the tyrosine kinome in melanoma reveals recurrent mutations in ERBB4.

31 March 2020

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Detection of copy number alterations in metastatic melanoma by a DNA fluorescence in situ hybridization probe panel and array comparative genomic hybridization: a southwest oncology group study (S9431).

31 March 2020

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Extra c-myc oncogene copies in high risk cutaneous malignant melanoma and melanoma metastases

31 March 2020

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An oncogenic role for ETV1 in melanoma

31 March 2020

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Frequent p16-independent inactivation of p14ARF in human melanoma

31 March 2020

1 reference

Reassessment of the TP53 mutation database in human disease by data mining with a library of TP53 missense mutations

31 March 2020

1 reference

Frequent mutation of BAP1 in metastasizing uveal melanomas

31 March 2020

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Genome-wide loss of heterozygosity and copy number analysis in melanoma using high-density single-nucleotide polymorphism arrays.

31 March 2020

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Phase II, open-label, single-arm trial of imatinib mesylate in patients with metastatic melanoma harboring c-Kit mutation or amplification

31 March 2020

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Multicenter phase II trial of the histone deacetylase inhibitor pyridylmethyl-N-{4-[(2-aminophenyl)-carbamoyl]-benzyl}-carbamate in pretreated metastatic melanoma

31 March 2020

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A SUMOylation-defective MITF germline mutation predisposes to melanoma and renal carcinoma

31 March 2020

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RAS mutations in cutaneous squamous-cell carcinomas in patients treated with BRAF inhibitors

31 March 2020

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RAF inhibitor resistance is mediated by dimerization of aberrantly spliced BRAF(V600E)

31 March 2020

1 reference

Melanoma whole-exome sequencing identifies (V600E)B-RAF amplification-mediated acquired B-RAF inhibitor resistance

31 March 2020

1 reference

Immune and clinical responses in patients with metastatic melanoma to CD34(+) progenitor-derived dendritic cell vaccine

31 March 2020

1 reference

12 December 2020

Vascular endothelial growth factor, interleukin 8, platelet-derived endothelial cell growth factor, and basic fibroblast growth factor promote angiogenesis and metastasis in human melanoma xenografts

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12 December 2020

Peptide-binding heat shock proteins in the endoplasmic reticulum: role in immune response to cancer and in antigen presentation.

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12 December 2020

Cloned dendritic cells can present exogenous antigens on both MHC class I and class II molecules

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12 December 2020

Differential expression of the cyclin-dependent kinase inhibitors p16 and p21 in the human melanocytic system

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12 December 2020

Chromosomal gains and losses in primary cutaneous melanomas detected by comparative genomic hybridization

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12 December 2020

Phase II study of the farnesyltransferase inhibitor R115777 in advanced melanoma (CALGB 500104)

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12 December 2020

Genetically modified tumor cell vaccines

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12 December 2020

Disruption of the MMAC1/PTEN gene by deletion or mutation is a frequent event in malignant melanoma.

1 reference

12 December 2020

Immunohistochemical determination of vascular endothelial growth factor (VEGF) overexpression in malignant melanoma

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12 December 2020

Suppression of BRAF(V599E) in human melanoma abrogates transformation

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12 December 2020

Immunological and clinical responses in metastatic renal cancer patients vaccinated with tumor RNA-transfected dendritic cells

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12 December 2020

c-Kit triggers dual phosphorylations, which couple activation and degradation of the essential melanocyte factor Mi.

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12 December 2020

Induction of tumor immunity by removing CD25+CD4+ T cells: a common basis between tumor immunity and autoimmunity

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12 December 2020

Expression of transforming growth factor-beta 2 in malignant melanoma correlates with the depth of tumor invasion. Implications for tumor progression

1 reference

12 December 2020

Differences in dendritic cells stimulated in vivo by tumors engineered to secrete granulocyte-macrophage colony-stimulating factor or Flt3-ligand.

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12 December 2020

Identifiers

DOI

10.1038/NRC3218

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Dimensions Publication ID

26 August 2017

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