Gene functional trade-offs and the evolution of pleiotropy. (Q36439810)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22982578%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

title

Gene functional trade-offs and the evolution of pleiotropy (English)

1 reference

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13 February 2020

1 reference

2

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13 February 2020

Frédéric Guillaume

series ordinal

1

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13 February 2020

author name string

Frédéric Guillaume

series ordinal

1

1 reference

14 August 2017

language of work or name

English

0 references

publication date

14 September 2012

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13 February 2020

number of pages

21

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inferred from page(s)

published in

Genetics

1 reference

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13 February 2020

volume

192

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13 February 2020

issue

4

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13 February 2020

page(s)

1389-1409

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22982578%20AND%20SRC:MED&resulttype=core&format=json

Evolution of functional specialization and division of labor

13 February 2020

cites work

1 reference

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Multiple routes to subfunctionalization and gene duplicate specialization

30 September 2017

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Organ and cell type-specific complementary expression patterns and regulatory neofunctionalization between duplicated genes in Arabidopsis thaliana

30 September 2017

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The pleiotropic structure of the genotype-phenotype map: the evolvability of complex organisms.

30 September 2017

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Genomic patterns of pleiotropy and the evolution of complexity

30 September 2017

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Maintenance of duplicate genes and their functional redundancy by reduced expression

30 September 2017

1 reference

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Enzyme promiscuity: a mechanistic and evolutionary perspective

30 September 2017

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The evolution of gene duplications: classifying and distinguishing between models

30 September 2017

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Macroevolutionary patterns of defense and pollination in Dalechampia vines: adaptation, exaptation, and evolutionary novelty

30 September 2017

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Temporal constraints on the incorporation of regulatory mutants in evolutionary pathways

30 September 2017

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Distinguishing among evolutionary models for the maintenance of gene duplicates

30 September 2017

1 reference

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Pervasive and persistent redundancy among duplicated genes in yeast

30 September 2017

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Escape from adaptive conflict after duplication in an anthocyanin pathway gene

30 September 2017

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The genetics of adaptive shape shift in stickleback: pleiotropy and effect size

30 September 2017

1 reference

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The distribution of fitness effects of new mutations

30 September 2017

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A global view of pleiotropy and phenotypically derived gene function in yeast

30 September 2017

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Toward a molecular understanding of pleiotropy

30 September 2017

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Diversification and specialization of HIV protease function during in vitro evolution

30 September 2017

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High-dimensional and large-scale phenotyping of yeast mutants.

30 September 2017

1 reference

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Noise in gene expression: origins, consequences, and control

30 September 2017

1 reference

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Optimality and evolutionary tuning of the expression level of a protein

30 September 2017

1 reference

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Rapid subfunctionalization accompanied by prolonged and substantial neofunctionalization in duplicate gene evolution

30 September 2017

1 reference

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The 'evolvability' of promiscuous protein functions

30 September 2017

1 reference

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Stochastic gene expression in fluctuating environments

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3512146

Evolution restricts the coexistence of specialists and generalists: the role of trade-off structure

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3512146

Perspective: Evolution and detection of genetic robustness

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3512146

The evolutionary origin of complex features

30 September 2017

1 reference

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Mechanisms of alternative pre-messenger RNA splicing

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3512146

General models of multilocus evolution

30 September 2017

1 reference

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Stochastic gene expression in a single cell

30 September 2017

1 reference

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Regulation of noise in the expression of a single gene

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3512146

The role of population size, pleiotropy and fitness effects of mutations in the evolution of overlapping gene functions

30 September 2017

1 reference

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The probability of duplicate gene preservation by subfunctionalization

30 September 2017

1 reference

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Preservation of duplicate genes by complementary, degenerative mutations

30 September 2017

1 reference

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Dissecting the regulatory circuitry of a eukaryotic genome

30 September 2017

1 reference

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Stochastic mechanisms in gene expression

30 September 2017

1 reference

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Metabolic flux and fitness

30 September 2017

1 reference

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Enzyme/crystallins: gene sharing as an evolutionary strategy

30 September 2017

1 reference

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Function of the Outer Membrane of Escherichia coli as a Permeability Barrier to Beta-Lactam Antibiotics

30 September 2017

1 reference

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Selection to minimise noise in living systems and its implications for the evolution of gene expression

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3512146

Seven types of pleiotropy.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3512146

Evolution of genetic redundancy

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3512146

Polymorphisms for genetic and ecological systems with weak coupling

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3512146

Application of method of small parameters to multi-niche population genetic models.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3512146

Individual-Level Bet Hedging in the Bacterium Sinorhizobium meliloti

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3512146

Evolution of specialization in a spatially continuous environment.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3512146

Heterogeneous patterns of gene-expression diversification in mammalian gene duplicates.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3512146

The evolution of epistasis and its links with genetic robustness, complexity and drift in a phenotypic model of adaptation

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3512146

Pleiotropic scaling of gene effects and the 'cost of complexity'.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3512146

Stochastic switching as a survival strategy in fluctuating environments

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3512146

Nemo: an evolutionary and population genetics programming framework.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3512146

Efficient attenuation of stochasticity in gene expression through post-transcriptional control.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3512146

The evolution of functionally novel proteins after gene duplication.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3512146

Live Where You Thrive: Joint Evolution of Habitat Choice and Local Adaptation Facilitates Specialization and Promotes Diversity

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3512146

The Effect of Multifunctionality on the Rate of Evolution in Yeast

4 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3512146

ADAPTATION AND THE COST OF COMPLEXITY

4 December 2018

1 reference

12 December 2020

Is modularity necessary for evolvability? Remarks on the relationship between pleiotropy and evolvability

1 reference

12 December 2020

Modularity and the cost of complexity

1 reference

12 December 2020

A negative relationship between mutation pleiotropy and fitness effect in yeast

1 reference

12 December 2020

FISHER'S MODEL AND THE GENOMICS OF ADAPTATION: RESTRICTED PLEIOTROPY, HETEROGENOUS MUTATION, AND PARALLEL EVOLUTION

1 reference

12 December 2020

Complexity, pleiotropy, and the fitness effect of mutations

1 reference

12 December 2020

THE POPULATION GENETICS OF ADAPTATION: THE DISTRIBUTION OF FACTORS FIXED DURING ADAPTIVE EVOLUTION.

1 reference

12 December 2020

QUANTITATIVE GENETIC ANALYSIS OF MULTIVARIATE EVOLUTION, APPLIED TO BRAIN:BODY SIZE ALLOMETRY.

1 reference

12 December 2020

10.1534/GENETICS.112.143214

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22982578%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22982578%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

PubMed publication ID

22982578

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22982578%20AND%20SRC:MED&resulttype=core&format=json