Resiniferatoxin for Pain Treatment: An Interventional Approach to Personalized Pain Medicine (Q36458451)

14 August 2017

Resiniferatoxin for Pain Treatment: An Interventional Approach to Personalized Pain Medicine (English)

1 reference

14 August 2017

Michael J Iadarola

1

1 reference

PMCID

4711370

14 August 2017

Gian Luigi Gonnella

series ordinal

2

1 reference

14 August 2017

8 March 2013

1 reference

14 August 2017

The open pain journal

1 reference

14 August 2017

6

1 reference

14 August 2017

95-107

1 reference

Creative Commons Attribution 4.0 International

14 August 2017

start time

8 March 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

1 reference

April 2022 Public Data File from Crossref

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Ablation of rat TRPV1-expressing Adelta/C-fibers with resiniferatoxin: analysis of withdrawal behaviors, recovery of function and molecular correlates

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Neurokinin-1 receptor antagonists: a comprehensive patent survey

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Signals to promote myelin formation and repair

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Prolonged analgesic response of cornea to topical resiniferatoxin, a potent TRPV1 agonist

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30 September 2017

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Pharmacological blockade of the vanilloid receptor TRPV1 elicits marked hyperthermia in humans

30 September 2017

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Perineural resiniferatoxin selectively inhibits inflammatory hyperalgesia

30 September 2017

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30 September 2017

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30 September 2017

Thermosensation and pain

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Deletion of vanilloid receptor 1-expressing primary afferent neurons for pain control

30 September 2017

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30 September 2017

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Lessons from peppers and peppermint: the molecular logic of thermosensation

30 September 2017

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Peripherally induced resiniferatoxin analgesia

30 September 2017

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Do some nerve cells release more than one transmitter?

30 September 2017

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Efficacy of cyclooxygenase-2-specific inhibitors

30 September 2017

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Ligand-induced dynamic membrane changes and cell deletion conferred by vanilloid receptor 1

30 September 2017

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Multiple messengers in descending serotonin neurons: localization and functional implications

30 September 2017

1 reference

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Sodium channels, excitability of primary sensory neurons, and the molecular basis of pain

30 September 2017

1 reference

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Immunocytochemical localization of the vanilloid receptor 1 (VR1): relationship to neuropeptides, the P2X3 purinoceptor and IB4 binding sites

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4711370

The capsaicin receptor: a heat-activated ion channel in the pain pathway

30 September 2017

1 reference

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A tetrodotoxin-resistant voltage-gated sodium channel expressed by sensory neurons

30 September 2017

1 reference

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The discovery of capsazepine, the first competitive antagonist of the sensory neuron excitants capsaicin and resiniferatoxin

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4711370

Effect of multiple dorsal rhizotomies on calcitonin gene-related peptide-like immunoreactivity in the lumbosacral dorsal spinal cord of the cat: a radioimmunoassay analysis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4711370

Essential role of Ret for defining non-peptidergic nociceptor phenotypes and functions in the adult mouse

30 September 2017

1 reference

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Anandamide activates vanilloid receptor 1 (VR1) at acidic pH in dorsal root ganglia neurons and cells ectopically expressing VR1.

28 June 2018

1 reference

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Calcitonin gene-related peptide immunoreactivity in the cat lumbosacral spinal cord and the effects of multiple dorsal rhizotomies

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4711370

Painful neuropathy: altered central processing maintained dynamically by peripheral input

28 June 2018

1 reference

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Tanezumab reduces osteoarthritic knee pain: results of a randomized, double-blind, placebo-controlled phase III trial.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4711370

Oral and cutaneous thermosensory profile of selective TRPV1 inhibition by ABT-102 in a randomized healthy volunteer trial

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4711370

Tanezumab for the treatment of pain from osteoarthritis of the knee.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4711370

The effect of pulsed radiofrequency current on mechanical allodynia induced with resiniferatoxin in rats

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4711370

The effect of wound instillation of a novel purified capsaicin formulation on postherniotomy pain: a double-blind, randomized, placebo-controlled study

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4711370

Enhancement of cutaneous nerve regeneration by 4-methylcatechol in resiniferatoxin-induced neuropathy

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4711370

Peripheral inflammation increases Scya2 expression in sensory ganglia and cytokine and endothelial related gene expression in inflamed tissue

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4711370

Sciatic nerve block with resiniferatoxin: an electron microscopic study of unmyelinated fibers in the rat.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4711370

Potential downsides of perfect pain relief

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4711370

Calcium regulation in individual peripheral sensory nerve terminals of the rat.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4711370

Effect of intravesical Resiniferatoxin (RTX) on lower urinary tract symptoms, urodynamic parameters, and quality of life of patients with urodynamic increased bladder sensation.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4711370

Intravesical resiniferatoxin for the treatment of interstitial cystitis: a randomized, double-blind, placebo controlled trial.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4711370

Selective ablation of nociceptive neurons for elimination of hyperalgesia and neurogenic inflammation

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4711370

Topographically distinct epidermal nociceptive circuits revealed by axonal tracers targeted to Mrgprd

21 September 2018

1 reference

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Isolectin B4 binding neurons are not present in the rat knee joint

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4711370

Vanilloid receptor 1 regulates multiple calcium compartments and contributes to Ca2+-induced Ca2+ release in sensory neurons.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4711370

Resiniferatoxin-induced loss of plasma membrane in vanilloid receptor expressing cells.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4711370

Calcium signaling in single peripheral sensory nerve terminals.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4711370

Selective and long-lasting neural blockade with resiniferatoxin prevents inflammatory pain hypersensitivity

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4711370

Comparison of [3H]resiniferatoxin binding by the vanilloid (capsaicin) receptor in dorsal root ganglia, spinal cord, dorsal vagal complex, sciatic and vagal nerve and urinary bladder of the rat.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4711370

Intravesical resiniferatoxin for the treatment of hypersensitive disorder: a randomized placebo controlled study

21 September 2018

1 reference

12 December 2020

Fate of novel painkiller mAbs hangs in balance

1 reference

12 December 2020

Lack of involvement of capsaicin-sensitive primary afferents in nerve-ligation injury induced tactile allodynia in rats

1 reference

12 December 2020

The potent irritancy of the daphnane orthoester, resiniferatoxin, exhibits features of a mixed aetiology

1 reference

12 December 2020

Intradermal injection of capsaicin in humans produces degeneration and subsequent reinnervation of epidermal nerve fibers: correlation with sensory function

1 reference

12 December 2020

Differential activation of spinal cord dynorphin and enkephalin neurons during hyperalgesia: evidence using cDNA hybridization

1 reference

12 December 2020

Increased spinal cord dynorphin mRNA during peripheral inflammation

1 reference

12 December 2020

Coexistence of glutamate and substance P in dorsal root ganglion neurons of the rat and monkey

1 reference

12 December 2020

Analysis of calcitonin gene-related peptide-like immunoreactivity in the cat dorsal spinal cord and dorsal root ganglia provide evidence for a multisegmental projection of nociceptive C-fiber primary afferents

1 reference

12 December 2020

Sprouting of noradrenergic fibers in hippocampus after medial septal lesions: contributions of the central and peripheral nervous systems

1 reference

12 December 2020

Ultrasound-guided peripheral nerve blockade

1 reference

12 December 2020

Prospective, randomized, double-blind study of safety and tolerability of intravesical resiniferatoxin (RTX) in interstitial cystitis (IC)

1 reference

12 December 2020

P2X3-mediated peripheral sensitization of neuropathic pain in resiniferatoxin-induced neuropathy

1 reference

12 December 2020

Sympathetic noradrenergic sprouting in response to central cholinergic denervation: A histochemical study of neuronal sprouting in the rat hippocampal formation

1 reference

12 December 2020

Perineural resiniferatoxin prevents the development of hyperalgesia produced by loose ligation of the sciatic nerve in rats

1 reference

12 December 2020

10.2174/1876386301306010095

Identifiers

DOI

0 references

PMCID

4711370

1 reference

14 August 2017

1 reference

PMCID

4711370