Modulation of apoptotic pathways by human papillomaviruses (HPV): mechanisms and implications for therapy. (Q36482809)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23250450%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

review article

7 references

27 July 2020

29 October 2020

16 December 2020

20 December 2020

22 August 2022

3 October 2022

Modulation of apoptotic pathways by human papillomaviruses (HPV): mechanisms and implications for therapy (English)

1 reference

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20 February 2020

1 reference

20 December 2020

evasion of host immune response

1 reference

host microbial interaction

25 September 2019

tumor virus infections

1 reference

21 October 2019

1 reference

3 November 2019

1 reference

27 July 2020

1 reference

29 October 2020

Papillomavirus infections

4 references

16 December 2020

20 December 2020

22 August 2022

3 October 2022

Penelope Duerksen-Hughes

series ordinal

3

1 reference

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20 February 2020

author name string

Chung-Hsiang Yuan

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1

1 reference

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20 February 2020

Maria Filippova

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2

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20 February 2020

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18 December 2012

12 references

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3 November 2019

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20 February 2020

27 July 2020

29 October 2020

16 December 2020

20 December 2020

22 August 2022

3 October 2022

12 references

23 March 2019

20 June 2019

25 September 2019

21 October 2019

3 November 2019

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20 February 2020

27 July 2020

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3 October 2022

4

1 reference

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issue

12

1 reference

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20 February 2020

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3831-3850

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Creative Commons Attribution 3.0 Unported

20 February 2020

copyright license

11 references

23 March 2019

20 June 2019

25 September 2019

21 October 2019

3 November 2019

27 July 2020

29 October 2020

16 December 2020

20 December 2020

22 August 2022

Effects of Epstein-Barr virus infection on the development of multiple myeloma after liver transplantation

3 October 2022

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1 reference

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Human papillomavirus disease in adolescents: management and prevention.

30 September 2017

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Cervical cancers require the continuous expression of the human papillomavirus type 16 E7 oncoprotein even in the presence of the viral E6 oncoprotein

30 September 2017

1 reference

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Genital human papillomavirus infections: current and prospective therapies

30 September 2017

1 reference

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Small molecule inhibitors of the HPV16-E6 interaction with caspase 8

30 September 2017

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Epstein-Barr virus nuclear antigen 3C stabilizes Gemin3 to block p53-mediated apoptosis

30 September 2017

1 reference

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Papillomavirus E5: the smallest oncoprotein with many functions

30 September 2017

1 reference

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30 September 2017

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30 September 2017

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Caspase-2 is required for DNA damage-induced expression of the CDK inhibitor p21(WAF1/CIP1)

30 September 2017

1 reference

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The human papillomavirus type 16 E5 oncoprotein inhibits epidermal growth factor trafficking independently of endosome acidification

30 September 2017

1 reference

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E1--E4-mediated keratin phosphorylation and ubiquitylation: a mechanism for keratin depletion in HPV16-infected epithelium

30 September 2017

1 reference

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Human papillomavirus type 16 E5 oncoprotein as a new target for cervical cancer treatment

30 September 2017

1 reference

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Human papillomavirus oncoproteins: pathways to transformation

30 September 2017

1 reference

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E6-associated protein is required for human papillomavirus type 16 E6 to cause cervical cancer in mice

30 September 2017

1 reference

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Development of small-molecule inhibitors of the group I p21-activated kinases, emerging therapeutic targets in cancer

30 September 2017

1 reference

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Viral TNF inhibitors as potential therapeutics

30 September 2017

1 reference

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Human papillomavirus type 16 E5 protein inhibits hydrogen-peroxide-induced apoptosis by stimulating ubiquitin-proteasome-mediated degradation of Bax in human cervical cancer cells

30 September 2017

1 reference

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The full-length isoform of human papillomavirus 16 E6 and its splice variant E6* bind to different sites on the procaspase 8 death effector domain

30 September 2017

1 reference

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Caspase-mediated protein kinase C-delta cleavage is necessary for apoptosis of vascular smooth muscle cells

30 September 2017

1 reference

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A novel interaction between the human papillomavirus type 16 E2 and E1--E4 proteins leads to stabilization of E2.

30 September 2017

1 reference

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Mapatumumab, a fully human agonistic monoclonal antibody that targets TRAIL-R1, in combination with gemcitabine and cisplatin: a phase I study.

30 September 2017

1 reference

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The human papillomavirus (HPV) E6* proteins from high-risk, mucosal HPVs can direct degradation of cellular proteins in the absence of full-length E6 protein

30 September 2017

1 reference

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Case records of the Massachusetts General Hospital. Case 10-2009. A 23-year-old woman with an abnormal Papanicolaou smear

30 September 2017

1 reference

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TRAIL agonists on clinical trials for cancer therapy: the promises and the challenges

30 September 2017

1 reference

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Complexes of human papillomavirus type 16 E6 proteins form pseudo-death-inducing signaling complex structures during tumor necrosis factor-mediated apoptosis.

30 September 2017

1 reference

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Ligand-based targeting of apoptosis in cancer: the potential of recombinant human apoptosis ligand 2/Tumor necrosis factor-related apoptosis-inducing ligand (rhApo2L/TRAIL).

30 September 2017

1 reference

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The interaction between human papillomavirus type 16 and FADD is mediated by a novel E6 binding domain.

30 September 2017

1 reference

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HPV E6 degradation of p53 and PDZ containing substrates in an E6AP null background

30 September 2017

1 reference

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Efficacy of a prophylactic adjuvanted bivalent L1 virus-like-particle vaccine against infection with human papillomavirus types 16 and 18 in young women: an interim analysis of a phase III double-blind, randomised controlled trial

30 September 2017

1 reference

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Human papillomavirus-16 E7 interacts with Siva-1 and modulates apoptosis in HaCaT human immortalized keratinocytes

30 September 2017

1 reference

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The large and small isoforms of human papillomavirus type 16 E6 bind to and differentially affect procaspase 8 stability and activity

30 September 2017

1 reference

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Extrinsic versus intrinsic apoptosis pathways in anticancer chemotherapy

30 September 2017

1 reference

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Partitioning viral genomes in mitosis: same idea, different targets

30 September 2017

1 reference

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Identification of inhibitors to papillomavirus type 16 E6 protein based on three-dimensional structures of interacting proteins

30 September 2017

1 reference

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An evidence-based review of medical and surgical treatments of genital warts.

30 September 2017

1 reference

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Accelerated degradation of FADD and procaspase 8 in cells expressing human papilloma virus 16 E6 impairs TRAIL-mediated apoptosis

30 September 2017

1 reference

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The global health burden of infection-associated cancers in the year 2002

30 September 2017

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Near death experiences: poxvirus regulation of apoptotic death

30 September 2017

1 reference

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Apoptosis: mechanisms and relevance in cancer

30 September 2017

1 reference

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The human papillomavirus 16 E6 protein can either protect or further sensitize cells to TNF: effect of dose

30 September 2017

1 reference

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30 September 2017

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The papillomavirus life cycle

30 September 2017

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Doxorubicin increases the effectiveness of Apo2L/TRAIL for tumor growth inhibition of prostate cancer xenografts

30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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The PIDDosome, a protein complex implicated in activation of caspase-2 in response to genotoxic stress

30 September 2017

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The human papillomavirus 16 E6 protein binds to Fas-associated death domain and protects cells from Fas-triggered apoptosis.

30 September 2017

1 reference

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Resistance to apoptosis of HPV 16-infected laryngeal cancer cells is associated with decreased Bak and increased Bcl-2 expression.

30 September 2017

1 reference

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Simultaneous human papilloma virus type 16 E7 and cdk inhibitor p21 expression induces apoptosis and cathepsin B activation

30 September 2017

1 reference

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The viral E4 protein is required for the completion of the cottontail rabbit papillomavirus productive cycle in vivo

30 September 2017

1 reference

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Regulation of proliferation, survival and apoptosis by members of the TNF superfamily

30 September 2017

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Apoptosis in systemic lupus erythematosus

30 September 2017

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Human papillomaviruses: targeting differentiating epithelial cells for malignant transformation

30 September 2017

1 reference

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30 September 2017

1 reference

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Human papillomavirus-induced carcinogenesis and the ubiquitin-proteasome system

30 September 2017

1 reference

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The human papillomavirus type 16 E5 protein impairs TRAIL- and FasL-mediated apoptosis in HaCaT cells by different mechanisms

30 September 2017

1 reference

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Genetic analysis of high-risk e6 in episomal maintenance of human papillomavirus genomes in primary human keratinocytes.

30 September 2017

1 reference

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Development of a human neuronal cell model for human immunodeficiency virus (HIV)-infected macrophage-induced neurotoxicity: apoptosis induced by HIV type 1 primary isolates and evidence for involvement of the Bcl-2/Bcl-xL-sensitive intrinsic apopto

30 September 2017

1 reference

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The human papillomavirus 16 E6 protein binds to tumor necrosis factor (TNF) R1 and protects cells from TNF-induced apoptosis.

30 September 2017

1 reference

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Biological activities and molecular targets of the human papillomavirus E7 oncoprotein

30 September 2017

1 reference

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E5 protein of human papillomavirus type 16 protects human foreskin keratinocytes from UV B-irradiation-induced apoptosis

30 September 2017

1 reference

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Caspase-10 is an initiator caspase in death receptor signaling

30 September 2017

1 reference

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HPV E6 and MAGUK protein interactions: determination of the molecular basis for specific protein recognition and degradation

30 September 2017

1 reference

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Defying death after DNA damage.

30 September 2017

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Induction of S phase and apoptosis by the human papillomavirus type 16 E7 protein are separable events in immortalized rodent fibroblasts.

30 September 2017

1 reference

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30 September 2017

The Hallmarks of Cancer

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Differences between CD95 type I and II cells detected with the CD95 ligand

30 September 2017

1 reference

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Interaction between the HPV-16 E2 transcriptional activator and p53.

30 September 2017

1 reference

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Human papillomavirus type 31 oncoproteins E6 and E7 are required for the maintenance of episomes during the viral life cycle in normal human keratinocytes

30 September 2017

1 reference

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An APAF-1.cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9

30 September 2017

1 reference

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Inhibition of Bak-induced apoptosis by HPV-18 E6.

30 September 2017

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Basal and human papillomavirus E6 oncoprotein-induced degradation of Myc proteins by the ubiquitin pathway

30 September 2017

1 reference

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Imiquimod, a patient-applied immune-response modifier for treatment of external genital warts.

30 September 2017

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Two CD95 (APO-1/Fas) signaling pathways

30 September 2017

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Differential requirements for conserved E2 binding sites in the life cycle of oncogenic human papillomavirus type 31

30 September 2017

1 reference

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Differential regulation of the pocket domains of the retinoblastoma family proteins by the HPV16 E7 oncoprotein.

30 September 2017

1 reference

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Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

30 September 2017

1 reference

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Caspase-3-generated fragment of gelsolin: effector of morphological change in apoptosis

30 September 2017

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Therapeutic approaches to genital warts

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3528293

Characterization of late gene transcripts expressed during vegetative replication of human papillomavirus type 31b

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3528293

Death effector domain-containing herpesvirus and poxvirus proteins inhibit both Fas- and TNFR1-induced apoptosis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3528293

Expression of the papillomavirus E2 protein in HeLa cells leads to apoptosis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3528293

The E5 oncoprotein of human papillomavirus type 16 transforms fibroblasts and effects the downregulation of the epidermal growth factor receptor in keratinocytes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3528293

Inhibition of p53 DNA binding by human papillomavirus E6 proteins

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3528293

Translation of the human papillomavirus type 16 E7 oncoprotein from bicistronic mRNA is independent of splicing events within the E6 open reading frame

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3528293

Structural and mutational analysis of E2 trans-activating proteins of papillomaviruses reveals three distinct functional domains.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3528293

Oncogenic and nononcogenic human genital papillomaviruses generate the E7 mRNA by different mechanisms

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3528293

The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3528293

A cellular protein mediates association of p53 with the E6 oncoprotein of human papillomavirus types 16 or 18

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3528293

Degradation of p53 can be targeted by HPV E6 sequences distinct from those required for p53 binding and trans-activation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3528293

Differentiation-induced and constitutive transcription of human papillomavirus type 31b in cell lines containing viral episomes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3528293

Apoptosis and disease: regulation and clinical relevance of programmed cell death

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3528293

Requirement of epidermal growth factor receptor for hyperplasia induced by E5, a high-risk human papillomavirus oncogene

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3528293

Crosstalk between the human papillomavirus E2 transcriptional activator and the E6 oncoprotein.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3528293

The immunology of genital human papilloma virus infection.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3528293

Growth and differentiation of human papillomavirus type 31b positive human cervical cell lines

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3528293

The adenovirus E3 region 14.7 kDa protein, heat and sodium arsenite inhibit the TNF-induced release of arachidonic acid

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3528293

Human papillomavirus E6 proteins mediate resistance to interferon-induced growth arrest through inhibition of p53 acetylation

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3528293

A cancer cell-specific inducer of apoptosis.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3528293

Effects of human papillomavirus type 16 oncoproteins on survivin gene expression.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3528293

HPV16 E5 protein disrupts the c-Cbl-EGFR interaction and EGFR ubiquitination in human foreskin keratinocytes

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3528293

Discovery of small-molecule inhibitors of the ATPase activity of human papillomavirus E1 helicase.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3528293

Transcription-independent triggering of the extrinsic pathway of apoptosis by human papillomavirus 18 E2 protein.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3528293

Effects of tumor necrosis factor-related apoptosis-inducing ligand alone and in combination with chemotherapeutic agents on patients' colon tumors grown in SCID mice

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3528293

Restoration of p53 expression sensitizes human papillomavirus type 16 immortalized human keratinocytes to CD95-mediated apoptosis

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3528293

Caspase-2 activation is redundant during seizure-induced neuronal death

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3528293

The human papillomavirus (HPV) 16 E2 protein induces apoptosis in the absence of other HPV proteins and via a p53-dependent pathway.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3528293

Induction of apoptosis in human keratinocytes containing mutated p53 alleles and its inhibition by both the E6 and E7 oncoproteins

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3528293

Selection of human cervical epithelial cells that possess reduced apoptotic potential to low-oxygen conditions.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3528293

Temporally distinct patterns of p53-dependent and p53-independent apoptosis during mouse lens development.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3528293

Evidence that apoptosis and terminal differentiation of epidermal keratinocytes are distinct processes

21 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.3390%2FV4123831

The E7 protein of human papillomavirus type 16 sensitizes primary human keratinocytes to apoptosis

21 January 2018

1 reference

12 December 2020

Molecular targets for human papillomaviruses: prospects for antiviral therapy

1 reference

12 December 2020

Involvement of TRAIL and its receptors in viral hepatitis

1 reference

12 December 2020

Apoptosis or retinoblastoma: alternative fates of photoreceptors expressing the HPV-16 E7 gene in the presence or absence of p53

1 reference

12 December 2020

Direct activation of caspase 8 by the proapoptotic E2 protein of HPV18 independent of adaptor proteins

1 reference

12 December 2020

E6 oncoprotein represses p53-dependent gene activation via inhibition of protein acetylation independently of inducing p53 degradation

1 reference

12 December 2020

HIV-specific differences in outcome of squamous cell carcinoma of the anal canal: a multicentric cohort study of HIV-positive patients receiving highly active antiretroviral therapy

1 reference

12 December 2020

Altered cell cycle regulation in the lens of HPV-16 E6 or E7 transgenic mice: implications for tumor suppressor gene function in development

1 reference

12 December 2020

Identifiers

DOI

10.3390/V4123831

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23250450%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23250450%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23250450%20AND%20SRC:MED&resulttype=core&format=json