Regulation of physiological responses to continuous and intermittent hypoxia by hypoxia-inducible factor 1. (Q36494841)

14 August 2017

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title

Regulation of physiological responses to continuous and intermittent hypoxia by hypoxia-inducible factor 1. (English)

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14 August 2017

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1

Gregg L Semenza

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14 August 2017

1 June 2006

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14 August 2017

Experimental Physiology

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14 August 2017

91

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14 August 2017

5

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14 August 2017

803-806

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A conserved family of prolyl-4-hydroxylases that modify HIF

14 August 2017

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.033498

Oxygen sensing requires mitochondrial ROS but not oxidative phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.033498

Role of HIF-1alpha in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.033498

C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.033498

Mitochondrial complex III is required for hypoxia-induced ROS production and cellular oxygen sensing

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.033498

Modulating the hypoxia-inducible factor signaling pathway: applications from cardiovascular disease to cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.033498

Regulation of hypoxia-inducible factor 1alpha is mediated by an O2-dependent degradation domain via the ubiquitin-proteasome pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.033498

HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.033498

Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1 alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.033498

Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.033498

Defective carotid body function and impaired ventilatory responses to chronic hypoxia in mice partially deficient for hypoxia-inducible factor 1 alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.033498

Defective vascularization of HIF-1alpha-null embryos is not associated with VEGF deficiency but with mesenchymal cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.033498

Altered metabolic responses to intermittent hypoxia in mice with partial deficiency of hypoxia-inducible factor-1alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.033498

Mitochondrial dysfunction resulting from loss of cytochrome c impairs cellular oxygen sensing and hypoxic HIF-alpha activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.033498

The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.033498

Functional analysis of an oxygen-regulated transcriptional enhancer lying 3' to the mouse erythropoietin gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.033498

HIF-1 alpha is required for solid tumor formation and embryonic vascularization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.033498

Hypoxia-inducible factor 1alpha (HIF-1alpha) protein is rapidly degraded by the ubiquitin-proteasome system under normoxic conditions. Its stabilization by hypoxia depends on redox-induced changes

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.033498

Development of novel therapeutic strategies that target HIF-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.033498

Hypoxia-inducible nuclear factors bind to an enhancer element located 3' to the human erythropoietin gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.033498

A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.033498

The Expression and Distribution of the Hypoxia-Inducible Factors HIF-1α and HIF-2α in Normal Human Tissues, Cancers, and Tumor-Associated Macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.033498

Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.033498

Purification and characterization of hypoxia-inducible factor 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.033498

Impaired physiological responses to chronic hypoxia in mice partially deficient for hypoxia-inducible factor 1alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.033498

HIF-1alpha binding to VHL is regulated by stimulus-sensitive proline hydroxylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.033498

Expression of hypoxia-inducible factor 1? in brain tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FEXPPHYSIOL.2006.033498

Regulation of the hypoxia-inducible transcription factor 1alpha by the ubiquitin-proteasome pathway

21 January 2018

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1113/EXPPHYSIOL.2006.033498

Hypoxia-inducible factor 1 levels vary exponentially over a physiologically relevant range of O2 tension

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1113/EXPPHYSIOL.2006.033498

Identifiers

DOI

10.1113/EXPPHYSIOL.2006.033498

1 reference

14 August 2017

1 reference

PubMed ID

16740642