4-1BB/4-1BBL interaction promotes obesity-induced adipose inflammation by triggering bidirectional inflammatory signaling in adipocytes/macrophages. (Q36500294)

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scientific article published on 17 December 2012

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English	4-1BB/4-1BBL interaction promotes obesity-induced adipose inflammation by triggering bidirectional inflammatory signaling in adipocytes/macrophages.	scientific article published on 17 December 2012

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22 February 2020

4-1BB/4-1BBL interaction promotes obesity-induced adipose inflammation by triggering bidirectional inflammatory signaling in adipocytes/macrophages (English)

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22 February 2020

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22 February 2020

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Teruo Kawada

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22 February 2020

author name string

Thai Hien Tu

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22 February 2020

Chu-Sook Kim

2

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22 February 2020

Byung-Sam Kim

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22 February 2020

Rina Yu

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22 February 2020

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17 December 2012

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22 February 2020

Mediators of Inflammation

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22 February 2020

2012

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22 February 2020

972629

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22 February 2020

copyright license

Creative Commons Attribution 3.0 Unported

1 January 2012

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copyright status

1 reference

April 2022 Public Data File from Crossref

TNF superfamily in inflammatory disease: translating basic insights

1 reference

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30 September 2017

Reverse signaling through the costimulatory ligand CD137L in epithelial cells is essential for natural killer cell-mediated acute tissue inflammation

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30 September 2017

Deficiency for costimulatory receptor 4-1BB protects against obesity-induced inflammation and metabolic disorders

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30 September 2017

LIGHT/TNFSF14 enhances adipose tissue inflammatory responses through its interaction with HVEM

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30 September 2017

CD137 ligand, a member of the tumor necrosis factor family, regulates immune responses via reverse signal transduction

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30 September 2017

Interactive changes between macrophages and adipocytes

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30 September 2017

CD137 ligand-mediated reverse signals increase cell viability and cytokine expression in murine myeloid cells: involvement of mTOR/p70S6 kinase and Akt.

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30 September 2017

CD8+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity

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30 September 2017

Multi-layered action mechanisms of CD137 (4-1BB)-targeted immunotherapies.

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30 September 2017

Adipocyte dysfunctions linking obesity to insulin resistance and type 2 diabetes

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30 September 2017

Mechanisms linking obesity with cardiovascular disease

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30 September 2017

Inflammation and metabolic disorders

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30 September 2017

Macrophages block insulin action in adipocytes by altering expression of signaling and glucose transport proteins.

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30 September 2017

The many roles of chemokines and chemokine receptors in inflammation

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30 September 2017

A paracrine loop between adipocytes and macrophages aggravates inflammatory changes: role of free fatty acids and tumor necrosis factor alpha

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30 September 2017

Biological activities of reverse signal transduction through CD137 ligand

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30 September 2017

4-1BB: still in the midst of darkness

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30 September 2017

4-1BB costimulatory signals preferentially induce CD8+ T cell proliferation and lead to the amplification in vivo of cytotoxic T cell responses

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30 September 2017

CD137-CD137 Ligand Interactions in Inflammation

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28 June 2018

The inflammatory receptor CD40 is expressed on human adipocytes: contribution to crosstalk between lymphocytes and adipocytes.

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28 June 2018

CD137 (4-1BB) deficiency reduces atherosclerosis in hyperlipidemic mice.

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21 September 2018

Attenuation of experimental autoimmune myocarditis by blocking T cell activation through 4-1BB pathway.

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21 September 2018

CD137 is expressed on blood vessel walls at sites of inflammation and enhances monocyte migratory activity.

1 reference

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21 September 2018

4-1BB-mediated immunotherapy of rheumatoid arthritis.

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21 September 2018

Capsaicin exhibits anti-inflammatory property by inhibiting IkB-a degradation in LPS-stimulated peritoneal macrophages

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21 September 2018

Signal transduction mechanisms of CD137 ligand in human monocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/23316108

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HVEM-deficient mice fed a high-fat diet are protected from adipose tissue inflammation and glucose intolerance

1 reference

https://pubmed.ncbi.nlm.nih.gov/23316108

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

4-1BB ligand-mediated costimulation of human T cells induces CD4 and CD8 T cell expansion, cytokine production, and the development of cytolytic effector function

1 reference

https://pubmed.ncbi.nlm.nih.gov/23316108

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD40L Deficiency Ameliorates Adipose Tissue Inflammation and Metabolic Manifestations of Obesity in Mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/23316108

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD137 is expressed in human atherosclerosis and promotes development of plaque inflammation in hypercholesterolemic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/23316108

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1155/2012/972629

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22 February 2020

1 reference

Europe PubMed Central

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22 February 2020

1 reference

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22 February 2020

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