Renal organic anion transporters (SLC22 family): expression, regulation, roles in toxicity, and impact on injury and disease. (Q36502382)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23054972%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

title

Renal organic anion transporters (SLC22 family): expression, regulation, roles in toxicity, and impact on injury and disease (English)

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10 March 2020

1

1 reference

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10 March 2020

Li Wang

series ordinal

2

1 reference

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10 March 2020

author name string

Douglas H Sweet

series ordinal

3

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10 March 2020

language of work or name

English

0 references

publication date

9 October 2012

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10 March 2020

1 reference

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10 March 2020

volume

15

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10 March 2020

issue

1

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10 March 2020

page(s)

53-69

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3-Monoglucuronyl-glycyrrhretinic acid is a substrate of organic anion transporters expressed in tubular epithelial cells and plays important roles in licorice-induced pseudoaldosteronism by inhibiting 11β-hydroxysteroid dehydrogenase 2.

10 March 2020

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Flavonoid conjugates interact with organic anion transporters (OATs) and attenuate cytotoxicity of adefovir mediated by organic anion transporter 1 (OAT1/SLC22A6).

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Genetic variants of human organic anion transporter 4 demonstrate altered transport of endogenous substrates

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Organic anion transporter 6 (Slc22a20) specificity and Sertoli cell-specific expression provide new insight on potential endogenous roles

30 September 2017

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Drug interaction between celecoxib and methotrexate in organic anion transporter 3-transfected renal cells and in rats in vivo

30 September 2017

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Transport of aminopterin by human organic anion transporters hOAT1 and hOAT3: Comparison with methotrexate

30 September 2017

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30 September 2017

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Identification of a novel organic anion transporter mediating carnitine transport in mouse liver and kidney

30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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Renal secretion of uric acid by organic anion transporter 2 (OAT2/SLC22A7) in human.

30 September 2017

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30 September 2017

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30 September 2017

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5-Hydroxy-L-tryptophan alters gaboxadol pharmacokinetics in rats: involvement of PAT1 and rOat1 in gaboxadol absorption and elimination

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30 September 2017

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30 September 2017

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Activation of protein kinase Czeta increases OAT1 (SLC22A6)- and OAT3 (SLC22A8)-mediated transport

30 September 2017

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30 September 2017

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30 September 2017

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Transcriptional regulation of human and mouse organic anion transporter 1 by hepatocyte nuclear factor 1 alpha/beta

30 September 2017

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Regulation of tissue-specific expression of the human and mouse urate transporter 1 gene by hepatocyte nuclear factor 1 alpha/beta and DNA methylation

30 September 2017

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Inhibition of human organic anion transporter 3 mediated pravastatin transport by gemfibrozil and the metabolites in humans

30 September 2017

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Hepatocyte nuclear factor-4{alpha} regulates the human organic anion transporter 1 gene in the kidney

30 September 2017

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Organic anion transporters of the SLC22 family: biopharmaceutical, physiological, and pathological roles

30 September 2017

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Regulation of the expression of human organic anion transporter 3 by hepatocyte nuclear factor 1alpha/beta and DNA methylation

30 September 2017

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Analyses of 5' regulatory region polymorphisms in human SLC22A6 (OAT1) and SLC22A8 (OAT3).

30 September 2017

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30 September 2017

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Prostaglandin E2 inhibits its own renal transport by downregulation of organic anion transporters rOAT1 and rOAT3.

30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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Expression levels of renal organic anion transporters (OATs) and their correlation with anionic drug excretion in patients with renal diseases

30 September 2017

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Human renal organic anion transporter 1-dependent uptake and toxicity of mercuric-thiol conjugates in Madin-Darby canine kidney cells

30 September 2017

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Organic anion and cation transporters occur in pairs of similar and similarly expressed genes

30 September 2017

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The antiviral nucleotide analogs cidofovir and adefovir are novel substrates for human and rat renal organic anion transporter 1.

30 September 2017

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Effect of probenecid on the distribution and elimination of ciprofloxacin in humans

30 September 2017

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Probenecid: an unexplained effect on cephalosporin pharmacology

30 September 2017

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Active Hydrophilic Components of the Medicinal Herb Salvia miltiorrhiza (Danshen) Potently Inhibit Organic Anion Transporters 1 (Slc22a6) and 3 (Slc22a8).

30 September 2017

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Aristolochic acid-induced destruction of organic ion transporters and fatty acid metabolic disorder in the kidney of rats

28 June 2018

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Analysis and update of the human solute carrier (SLC) gene superfamily

28 June 2018

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Human organic anion transporter 3 gene is regulated constitutively and inducibly via a cAMP-response element

28 June 2018

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Molecular cloning and characterization of a human urate transporter (hURAT1) gene promoter

28 June 2018

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PAH extraction and estimation of plasma flow in human postischemic acute renal failure

28 June 2018

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Inhibition of renal tubular transport of methotrexate by probenecid

28 June 2018

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Effects of probenecid on furosemide kinetics and natriuresis in man

28 June 2018

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Potential for food-drug interactions by dietary phenolic acids on human organic anion transporters 1 (SLC22A6), 3 (SLC22A8), and 4 (SLC22A11).

28 June 2018

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Inhibitory effect of caffeic acid on human organic anion transporters hOAT1 and hOAT3: a novel candidate for food-drug interaction

21 September 2018

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Interactions of human organic anion transporter 1 (hOAT1) with substances associated with forensic toxicology

21 September 2018

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Inhibitory effects of ketoconazole and rifampin on OAT1 and OATP1B1 transport activities: considerations on drug-drug interactions

21 September 2018

1 reference

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In vitro risk assessment of AZD9056 perpetrating a transporter-mediated drug-drug interaction with methotrexate

21 September 2018

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Human urate transporter 1 (hURAT1) mediates the transport of orotate

21 September 2018

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Organic anion transporter 3 mediates the efflux transport of an amphipathic organic anion, dehydroepiandrosterone sulfate, across the blood-brain barrier in mice

21 September 2018

1 reference

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Inhibitory effect of selective cyclooxygenase-2 inhibitor lumiracoxib on human organic anion transporters hOAT1 and hOAT3.

21 September 2018

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Concentration-dependent inhibitory effect of irbesartan on renal uric acid transporters

21 September 2018

1 reference

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Characterization of cellular uptake of perfluorooctanoate via organic anion-transporting polypeptide 1A2, organic anion transporter 4, and urate transporter 1 for their potential roles in mediating human renal reabsorption of perfluorocarboxylates

21 September 2018

1 reference

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Preclinical and clinical evidence for the collaborative transport and renal secretion of an oxazolidinone antibiotic by organic anion transporter 3 (OAT3/SLC22A8) and multidrug and toxin extrusion protein 1 (MATE1/SLC47A1).

21 September 2018

1 reference

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Interactions of human organic anion transporters with aristolochic acids

21 September 2018

1 reference

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Low-dose indomethacin after ischemic acute kidney injury prevents downregulation of Oat1/3 and improves renal outcome

21 September 2018

1 reference

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Molecular evidence for an involvement of organic anion transporters (OATs) in aristolochic acid nephropathy.

21 September 2018

1 reference

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COX-2 inhibition attenuates endotoxin-induced downregulation of organic anion transporters in the rat renal cortex

21 September 2018

1 reference

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Renal organic anion transporter 1 is maldistributed and diminishes in proximal tubule cells but increases in vasculature after ischemia and reperfusion

21 September 2018

1 reference

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Aristolochic acid induces proximal tubule apoptosis and epithelial to mesenchymal transformation

21 September 2018

1 reference

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Selective toxicity of aristolochic acids I and II.

21 September 2018

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Downregulation of organic anion transporters OAT1 and OAT3 correlates with impaired secretion of para-aminohippurate after ischemic acute renal failure in rats.

21 September 2018

1 reference

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Alterations in transporter expression in liver, kidney, and duodenum after targeted disruption of the transcription factor HNF1alpha.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3535093

Early proximal tubule injury in experimental aristolochic acid nephropathy: functional and histological studies

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3535093

Altered renal elimination of organic anions in rats with chronic renal failure

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3535093

The dietary polyphenol ellagic acid is a potent inhibitor of hOAT1.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3535093

Stability and biotransformation of various dietary anthocyanins in vitro

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3535093

Rat renal cortical OAT1 and OAT3 exhibit gender differences determined by both androgen stimulation and estrogen inhibition

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3535093

Acute nephrotoxicity of aristolochic acids in mice

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3535093

Gemfibrozil increases plasma pravastatin concentrations and reduces pravastatin renal clearance

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3535093

Down-regulation of rat organic cation transporter rOCT2 by 5/6 nephrectomy

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3535093

Stenosis-dependent role of nitric oxide and prostaglandins in chronic renal ischemia

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3535093

Antioxidant activities, total phenolics and HPLC analyses of the phenolic compounds of extracts from common Mediterranean plants

21 September 2018

1 reference

12 December 2020

In Vitro and In Vivo Assessment of Renal Drug Transporters in the Disposition of Mesna and Dimesna

1 reference

12 December 2020

Downregulation of organic anion transporters in rat kidney under ischemia/reperfusion-induced acute [corrected] renal failure

1 reference

12 December 2020

Critical role of organic anion transporters 1 and 3 in kidney accumulation and toxicity of aristolochic acid I

1 reference

12 December 2020

The human organic anion transporter genes OAT5 and OAT7 are transactivated by hepatocyte nuclear factor-1α (HNF-1α)

1 reference

12 December 2020

Urinary organic anion transporter protein profiles in AKI

1 reference

12 December 2020

Association of intergenic polymorphism of organic anion transporter 1 and 3 genes with hypertension and blood pressure response to hydrochlorothiazide

1 reference

12 December 2020

Organic anion transporters involved in the excretion of bestatin in the kidney

1 reference

12 December 2020

Alteration in renal organic anion transporter 1 after ischemia/reperfusion in cadaveric renal allografts

1 reference

12 December 2020

Plant secondary metabolites and gut health: the case for phenolic acids

1 reference

12 December 2020

Organic anion transporter 1 (OAT1) involved in renal cell transport of aristolochic acid I

1 reference

12 December 2020

Regulation of tissue-specific expression of renal organic anion transporters by hepatocyte nuclear factor 1 α/β and DNA methylation

1 reference

12 December 2020

LFB1 and LFB3 homeoproteins are sequentially expressed during kidney development

1 reference

12 December 2020

Acute Renal Failure in Critically Ill Patients A Multinational, Multicenter Study

1 reference

12 December 2020

10.1208/S12248-012-9413-Y

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23054972%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

10 March 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23054972%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

PubMed publication ID

23054972

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23054972%20AND%20SRC:MED&resulttype=core&format=json