Calcium sensing receptors and calcium oscillations: calcium as a first messenger (Q36510503)

14 August 2017

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title

Calcium sensing receptors and calcium oscillations: calcium as a first messenger (English)

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14 August 2017

Gerda E Breitwieser

1

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14 August 2017

publication date

1 January 2006

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Current Topics in Developmental Biology

14 August 2017

published in

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14 August 2017

volume

73

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14 August 2017

page(s)

85-114

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Interaction of the calcium-sensing receptor and filamin, a potential scaffolding protein

14 August 2017

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Rho and Rac take center stage

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Amino acids in the second and third intracellular loops of the parathyroid Ca2+-sensing receptor mediate efficient coupling to phospholipase C.

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Divalent cations suppress 3',5'-adenosine monophosphate accumulation by stimulating a pertussis toxin-sensitive guanine nucleotide-binding protein in cultured bovine parathyroid cells

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7 January 2021

Extracellular polyamines regulate fluid secretion in rat colonic crypts via the extracellular calcium-sensing receptor

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7 January 2021

L-amino acid sensing by the calcium-sensing receptor: a general mechanism for coupling protein and calcium metabolism?

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7 January 2021

L-amino acids regulate parathyroid hormone secretion

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7 January 2021

Marriage of the flytrap and the serpent

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7 January 2021

Pharmacology and functions of metabotropic glutamate receptors

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7 January 2021

Mitogen-Activated Protein Kinase Cascade in Human Normal and Tumoral Parathyroid Cells

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7 January 2021

Sensitivity of CaM kinase II to the frequency of Ca2+ oscillations

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7 January 2021

Evidence that Ca(2+) cycling by the plasma membrane Ca(2+)-ATPase increases the 'excitability' of the extracellular Ca(2+)-sensing receptor

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7 January 2021

Calcium oscillations increase the efficiency and specificity of gene expression

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7 January 2021

Mutational analysis of the cysteines in the extracellular domain of the human Ca2+ receptor: effects on cell surface expression, dimerization and signal transduction

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7 January 2021

Developmental and adult expression of rat calcium-sensing receptor transcripts in neurons and oligodendrocytes.

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7 January 2021

Desensitization of G protein-coupled receptors and neuronal functions

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7 January 2021

Mutagenesis and modeling of the GABAB receptor extracellular domain support a venus flytrap mechanism for ligand binding

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7 January 2021

A carboxyl-terminal domain controls the cooperativity for extracellular Ca2+ activation of the human calcium sensing receptor. A study with receptor-green fluorescent protein fusions

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7 January 2021

Points of convergence between Ca2+ and Ras signalling pathways.

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7 January 2021

Ligand binding to the amino-terminal domain of the mGluR4 subtype of metabotropic glutamate receptor

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7 January 2021

A novel family of putative pheromone receptors in mammals with a topographically organized and sexually dimorphic distribution

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7 January 2021

Filamin-A binds to the carboxyl-terminal tail of the calcium-sensing receptor, an interaction that participates in CaR-mediated activation of mitogen-activated protein kinase

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7 January 2021

A mouse model of human familial hypocalciuric hypercalcemia and neonatal severe hyperparathyroidism

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7 January 2021

Cloning, expression, and gene structure of a G protein-coupled glutamate receptor from rat brain

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7 January 2021

Activating calcium-sensing receptor mutation in the mouse is associated with cataracts and ectopic calcification

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7 January 2021

Naturally occurring mutations of the extracellular Ca2+-sensing receptor: implications for its structure and function

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7 January 2021

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7 January 2021

The Venus's-flytrap and cysteine-rich domains of the human Ca2+ receptor are not linked by disulfide bonds

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7 January 2021

Identification of acidic residues in the extracellular loops of the seven-transmembrane domain of the human Ca2+ receptor critical for response to Ca2+ and a positive allosteric modulator

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7 January 2021

A region in the seven-transmembrane domain of the human Ca2+ receptor critical for response to Ca2+.

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7 January 2021

[Ca(2+)](i) oscillation frequency regulates agonist-stimulated NF-kappaB transcriptional activity

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7 January 2021

Modulation of interprotomer relationships is important for activation of dimeric calcium-sensing receptor

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7 January 2021

Calcium sensing receptor forms complex with and is up-regulated by caveolin-1 in cultured human osteosarcoma (Saos-2) cells

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7 January 2021

Heterodimerization of a functional GABAB receptor is mediated by parallel coiled-coil alpha-helices

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7 January 2021

Expression cloning of GABA(B) receptors uncovers similarity to metabotropic glutamate receptors

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7 January 2021

N2-benzyl-N1-(1-(1-naphthyl)ethyl)-3-phenylpropane-1,2-diamines and conformationally restrained indole analogues: development of calindol as a new calcimimetic acting at the calcium sensing receptor

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7 January 2021

N(1)-Arylsulfonyl-N(2)-(1-(1-naphthyl)ethyl)-1,2-diaminocyclohexanes: a new class of calcilytic agents acting at the calcium-sensing receptor

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7 January 2021

Regulation of MAP kinase by calcium-sensing receptor in bovine parathyroid and CaR-transfected HEK293 cells

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7 January 2021

m-Calpain colocalizes with the calcium-sensing receptor (CaR) in caveolae in parathyroid cells and participates in degradation of the CaR.

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7 January 2021

Decreased expression of caveolin-1 and altered regulation of mitogen-activated protein kinase in cultured bovine parathyroid cells and human parathyroid adenomas

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7 January 2021

The calcium-sensing receptor is required for normal calcium homeostasis independent of parathyroid hormone

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7 January 2021

Regulation of murine fetal-placental calcium metabolism by the calcium-sensing receptor

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7 January 2021

Structural basis of glutamate recognition by a dimeric metabotropic glutamate receptor

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7 January 2021

Cell-permeant caged InsP3 ester shows that Ca2+ spike frequency can optimize gene expression

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7 January 2021

Depolarizing response of rat parathyroid cells to divalent cations

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7 January 2021

Sequence and expression of a metabotropic glutamate receptor

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7 January 2021

A multigene family encoding a diverse array of putative pheromone receptors in mammals

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7 January 2021

Functional calcium-sensing receptors in rat fibroblasts are required for activation of SRC kinase and mitogen-activated protein kinase in response to extracellular calcium

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7 January 2021

RhoA interaction with inositol 1,4,5-trisphosphate receptor and transient receptor potential channel-1 regulates Ca2+ entry. Role in signaling increased endothelial permeability

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7 January 2021

Mechanisms of Ca(2+)-dependent transcription

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7 January 2021

Calcium sensing receptor activation by a calcimimetic suggests a link between cooperativity and intracellular calcium oscillations

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7 January 2021

Homology modeling of the transmembrane domain of the human calcium sensing receptor and localization of an allosteric binding site

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7 January 2021

The Venus Fly Trap domain of the extracellular Ca2+ -sensing receptor is required for L-amino acid sensing

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7 January 2021

Intracellular calcium dependence of gene expression in single T lymphocytes

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7 January 2021

Cytosolic Ca2+ and the regulation of secretion in parathyroid cells

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7 January 2021

Calcimimetics with potent and selective activity on the parathyroid calcium receptor

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7 January 2021

Protein kinase C as a molecular machine for decoding calcium and diacylglycerol signals

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7 January 2021

The ligand-binding domain in metabotropic glutamate receptors is related to bacterial periplasmic binding proteins

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7 January 2021

Expression and purification of the extracellular ligand binding region of metabotropic glutamate receptor subtype 1.

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7 January 2021

Dimerization of the calcium-sensing receptor occurs within the extracellular domain and is eliminated by Cys --> Ser mutations at Cys101 and Cys236.

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7 January 2021

Calcium-sensing receptor mutations in familial benign hypercalcemia and neonatal hyperparathyroidism

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7 January 2021

Functional characterization of calcium-sensing receptor mutations expressed in human embryonic kidney cells

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7 January 2021

Multiple signaling states of G-protein-coupled receptors

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7 January 2021

Positive and negative allosteric modulators of the Ca2+-sensing receptor interact within overlapping but not identical binding sites in the transmembrane domain

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7 January 2021

Modeling and Mutagenesis of the Binding Site of Calhex 231, a Novel Negative Allosteric Modulator of the Extracellular Ca2+-sensing Receptor

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7 January 2021

Calcium-sensing receptor activation of rho involves filamin and rho-guanine nucleotide exchange factor

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7 January 2021

Activation mechanism of the heterodimeric GABA(B) receptor

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7 January 2021

Allosteric functioning of dimeric class C G-protein-coupled receptors.

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7 January 2021

pH Sensing by the calcium-sensing receptor

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7 January 2021

Sodium and ionic strength sensing by the calcium receptor

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7 January 2021

The carboxyl terminus of the human calcium receptor. Requirements for cell-surface expression and signal transduction.

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7 January 2021

Identification of the cysteine residues in the amino-terminal extracellular domain of the human Ca(2+) receptor critical for dimerization. Implications for function of monomeric Ca(2+) receptor

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7 January 2021

The role of cysteines and charged amino acids in extracellular loops of the human Ca(2+) receptor in cell surface expression and receptor activation processes

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7 January 2021

Evidence for distinct cation and calcimimetic compound (NPS 568) recognition domains in the transmembrane regions of the human Ca2+ receptor

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7 January 2021

Calindol, a positive allosteric modulator of the human Ca(2+) receptor, activates an extracellular ligand-binding domain-deleted rhodopsin-like seven-transmembrane structure in the absence of Ca(2+).

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7 January 2021

Amino acid-stimulated Ca2+ oscillations produced by the Ca2+-sensing receptor are mediated by a phospholipase C/inositol 1,4,5-trisphosphate-independent pathway that requires G12, Rho, filamin-A, and the actin cytoskeleton

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7 January 2021

Wellcome Prize Lecture. Cell surface, ion-sensing receptors

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7 January 2021

The role of the calcium-sensing receptor in cancer

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7 January 2021

Cloned and expressed rat Ca2+-sensing receptor.

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7 January 2021

A new multigene family of putative pheromone receptors

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https://api.crossref.org/works/10.1016%2FS0070-2153%2805%2973003-9

7 January 2021

Transcriptional and post-transcriptional regulation of PTH gene expression by vitamin D, calcium and phosphate

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7 January 2021

Delineating a Ca2+ binding pocket within the venus flytrap module of the human calcium-sensing receptor

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7 January 2021

Defects in G protein-coupled signal transduction in human disease

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7 January 2021

Filamins as integrators of cell mechanics and signalling

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7 January 2021

Structure and function of G protein-coupled receptors

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7 January 2021

Ligand-induced rearrangement of the dimeric metabotropic glutamate receptor 1alpha.

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7 January 2021

The calcium-sensing receptor in normal physiology and pathophysiology: a review

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7 January 2021

Calcium-sensing receptor stimulates PTHrP release by pathways dependent on PKC, p38 MAPK, JNK, and ERK1/2 in H-500 cells

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7 January 2021

NFAT functions as a working memory of Ca2+ signals in decoding Ca2+ oscillation

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7 January 2021

Structural views of the ligand-binding cores of a metabotropic glutamate receptor complexed with an antagonist and both glutamate and Gd3+.

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7 January 2021

Rescue of the skeletal phenotype in CasR-deficient mice by transfer onto the Gcm2 null background

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7 January 2021

Calcium receptor-mediated intracellular signalling

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7 January 2021

Aminoglycosides induce acute cell signaling and chronic cell death in renal cells that express the calcium-sensing receptor

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7 January 2021

N-acetylaspartylglutamate selectively activates mGluR3 receptors in transfected cells

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7 January 2021

The role of endogenous human Trp4 in regulating carbachol-induced calcium oscillations in HEK-293 cells

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7 January 2021

Activation of p42/44 and p38 mitogen-activated protein kinases by extracellular calcium-sensing receptor agonists induces mitogenic responses in the mouse osteoblastic MC3T3-E1 cell line

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7 January 2021

Hypocalcemia increases and hypercalcemia decreases the steady-state level of parathyroid hormone messenger RNA in the rat.

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7 January 2021

Calcium-sensing receptor activation stimulates parathyroid hormone-related protein secretion in prostate cancer cells: role of epidermal growth factor receptor transactivation

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7 January 2021

Role of Ca2+ feedback on single cell inositol 1,4,5-trisphosphate oscillations mediated by G-protein-coupled receptors.

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7 January 2021

Amino acids and Ca2+ stimulate different patterns of Ca2+ oscillations through the Ca2+-sensing receptor

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7 January 2021

Ca2+-stimulated Ca2+ oscillations produced by the Ca2+-sensing receptor require negative feedback by protein kinase C.

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7 January 2021

NCD3G: a novel nine-cysteine domain in family 3 GPCRs

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7 January 2021

High affinity interaction with filamin A protects against calcium-sensing receptor degradation.

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7 January 2021

Three adjacent serines in the extracellular domains of the CaR are required for L-amino acid-mediated potentiation of receptor function

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7 January 2021

The Ca2+-sensing receptor: a target for polyamines

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https://api.crossref.org/works/10.1016%2FS0070-2153%2805%2973003-9

7 January 2021

New aspects in the control of parathyroid hormone secretion

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2805%2973003-9

7 January 2021

10.1016/S0070-2153(05)73003-9

Identifiers

DOI

1 reference

14 August 2017

1 reference