Systemic administration of a bispecific antibody targeting EGFRvIII successfully treats intracerebral glioma. (Q36512160)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23248284%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

title

Systemic administration of a bispecific antibody targeting EGFRvIII successfully treats intracerebral glioma (English)

1 reference

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20 February 2020

1 reference

6

1 reference

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20 February 2020

John Sampson

10

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20 February 2020

author name string

Bryan D Choi

1

1 reference

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20 February 2020

Chien-Tsun Kuan

2

1 reference

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20 February 2020

Mingqing Cai

3

1 reference

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20 February 2020

Gary E Archer

4

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20 February 2020

Duane A Mitchell

5

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20 February 2020

Luis Sanchez-Perez

7

1 reference

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20 February 2020

Ira Pastan

8

1 reference

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20 February 2020

Darell D Bigner

9

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20 February 2020

language of work or name

English

0 references

publication date

17 December 2012

1 reference

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Proceedings of the National Academy of Sciences of the United States of America

20 February 2020

published in

1 reference

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20 February 2020

volume

110

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20 February 2020

issue

1

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20 February 2020

page(s)

270-275

1 reference

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Immunopharmacologic response of patients with B-lineage acute lymphoblastic leukemia to continuous infusion of T cell-engaging CD19/CD3-bispecific BiTE antibody blinatumomab

20 February 2020

cites work

1 reference

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Cancer immunotherapy comes of age

30 September 2017

1 reference

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Bispecific antibodies engage T cells for antitumor immunotherapy

30 September 2017

1 reference

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CD8+ T-cell infiltrate in newly diagnosed glioblastoma is associated with long-term survival.

30 September 2017

1 reference

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Case report of a serious adverse event following the administration of T cells transduced with a chimeric antigen receptor recognizing ERBB2

30 September 2017

1 reference

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EGFRvIII-targeted vaccination therapy of malignant glioma

30 September 2017

1 reference

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Bispecific T-cell engaging antibodies for cancer therapy

30 September 2017

1 reference

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Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial

30 September 2017

1 reference

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Tumor regression in cancer patients by very low doses of a T cell-engaging antibody

30 September 2017

1 reference

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Dose translation from animal to human studies revisited

30 September 2017

1 reference

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A phase I clinical trial with monoclonal antibody ch806 targeting transitional state and mutant epidermal growth factor receptors

30 September 2017

1 reference

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Cancer regression in patients after transfer of genetically engineered lymphocytes

30 September 2017

1 reference

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Cytokine storm in a phase 1 trial of the anti-CD28 monoclonal antibody TGN1412

30 September 2017

1 reference

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Induction of regular cytolytic T cell synapses by bispecific single-chain antibody constructs on MHC class I-negative tumor cells

30 September 2017

1 reference

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Engineered antibody fragments and the rise of single domains

30 September 2017

1 reference

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The ins and outs of T-lymphocyte trafficking to the CNS: anatomical sites and molecular mechanisms

30 September 2017

1 reference

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Cancer immunotherapy: moving beyond current vaccines

30 September 2017

1 reference

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Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer

30 September 2017

1 reference

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Adoptive-cell-transfer therapy for the treatment of patients with cancer

30 September 2017

1 reference

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Cancer regression and autoimmunity in patients after clonal repopulation with antitumor lymphocytes

30 September 2017

1 reference

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Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2.

30 September 2017

1 reference

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Fluorescence-guided resection of glioblastoma multiforme by using 5-aminolevulinic acid-induced porphyrins: a prospective study in 52 consecutive patients

30 September 2017

1 reference

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Increased binding affinity enhances targeting of glioma xenografts by EGFRvIII-specific scFv

30 September 2017

1 reference

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Treatment of chronic lymphocytic leukemia with genetically targeted autologous T cells: case report of an unforeseen adverse event in a phase I clinical trial

30 September 2017

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28 June 2018

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Effects of treatment on long-term survivors with malignant astrocytomas

28 June 2018

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Effector T-cell infiltration positively impacts survival of glioblastoma patients and is impaired by tumor-derived TGF-β.

28 June 2018

1 reference

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Epitope distance to the target cell membrane and antigen size determine the potency of T cell-mediated lysis by BiTE antibodies specific for a large melanoma surface antigen

21 September 2018

1 reference

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Supraagonistic, bispecific single-chain antibody purified from the serum of cloned, transgenic cows induces T-cell-mediated killing of glioblastoma cells in vitro and in vivo.

21 September 2018

1 reference

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Immunosuppressive properties of anti-CD3 single-chain Fv and diabody.

21 September 2018

1 reference

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Pharmacokinetics and tumor localization of 131I-labeled anti-tenascin monoclonal antibody 81C6 in patients with gliomas and other intracranial malignancies.

21 September 2018

1 reference

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Human CD3 Transgenic Mice: Preclinical Testing of Antibodies Promoting Immune Tolerance

21 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23248284

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

T cell costimulus-independent and very efficacious inhibition of tumor growth in mice bearing subcutaneous or leukemic human B cell lymphoma xenografts by a CD19-/CD3- bispecific single-chain antibody construct

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23248284

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1219817110

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23248284%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

0 references

1 reference

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20 February 2020

PubMed publication ID

23248284

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23248284%20AND%20SRC:MED&resulttype=core&format=json