Viral antigen density and confinement time regulate the reactivity pattern of CD4 T-cell responses to vaccinia virus infection (Q36512323)

14 August 2017

Viral antigen density and confinement time regulate the reactivity pattern of CD4 T-cell responses to vaccinia virus infection (English)

1 reference

14 August 2017

vaccinia virus

1 reference

Vijay Vanguri

1

1 reference

14 August 2017

Christopher C Govern

series ordinal

2

1 reference

14 August 2017

Rebecca Smith

series ordinal

3

1 reference

14 August 2017

Eric S Huseby

series ordinal

4

1 reference

14 August 2017

language of work or name

English

0 references

publication date

17 December 2012

1 reference

Proceedings of the National Academy of Sciences of the United States of America

14 August 2017

1 reference

14 August 2017

110

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14 August 2017

1

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14 August 2017

288-293

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Kinetics and mechanics of two-dimensional interactions between T cell receptors and different activating ligands

14 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3538251

How the TCR balances sensitivity and specificity for the recognition of self and pathogens.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3538251

A Role for Differential Variable Gene Pairing in Creating T Cell Receptors Specific for Unique Major Histocompatibility Ligands

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3538251

Strength of TCR-peptide/MHC interactions and in vivo T cell responses

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3538251

Evolving concepts of specificity in immune reactions

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3538251

Attenuated T cell responses to a high-potency ligand in vivo

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3538251

The in situ dynamics of dendritic cell interactions

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3538251

Heterologous immunity between viruses

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3538251

Effects of thymic selection of the T-cell repertoire on HLA class I-associated control of HIV infection

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3538251

Fast on-rates allow short dwell time ligands to activate T cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3538251

The kinetics of two-dimensional TCR and pMHC interactions determine T-cell responsiveness.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3538251

TCR-peptide-MHC interactions in situ show accelerated kinetics and increased affinity.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3538251

Dependence of T cell antigen recognition on T cell receptor-peptide MHC confinement time

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3538251

Rapid culling of the CD4+ T cell repertoire in the transition from effector to memory

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3538251

Crossreactive T Cells Spotlight the Germline Rules for αβ T Cell-Receptor Interactions with MHC Molecules

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3538251

T cell sensing of antigen dose governs interactive behavior with dendritic cells and sets a threshold for T cell activation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3538251

The T cell repertoire in infection and vaccination: implications for control of persistent viruses

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3538251

Polyspecificity of T cell and B cell receptor recognition

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3538251

Antigen persistence is required throughout the expansion phase of a CD4(+) T cell response

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3538251

How T cells 'see' antigen

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3538251

Epitope dominance, competition and T cell affinity maturation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3538251

Positive and negative selection of T cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3538251

The proliferative capacity of individual naive CD4(+) T cells is amplified by prolonged T cell antigen receptor triggering

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3538251

The induction of virus-specific CTL as a function of increasing epitope expression: responses rise steadily until excessively high levels of epitope are attained.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3538251

An inverse relationship between T cell receptor affinity and antigen dose during CD4(+) T cell responses in vivo and in vitro

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3538251

Evolution of a complex T cell receptor repertoire during primary and recall bacterial infection

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3538251

Kinetics of T-cell receptor binding to peptide/I-Ek complexes: correlation of the dissociation rate with T-cell responsiveness

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3538251

Kinetic proofreading in T-cell receptor signal transduction

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3538251

Extent of T cell receptor ligation can determine the functional differentiation of naive CD4+ T cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3538251

Molecular mimicry in T cell-mediated autoimmunity: viral peptides activate human T cell clones specific for myelin basic protein

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3538251

Mapping T-cell receptor–peptide contacts by variant peptide immunization of single-chain transgenics

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3538251

Peptide dose, affinity, and time of differentiation can contribute to the Th1/Th2 cytokine balance.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3538251

A kinetic basis for T cell receptor repertoire selection during an immune response

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3538251

TCR ligand discrimination is enforced by competing ERK positive and SHP-1 negative feedback pathways

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3538251

Direct link between mhc polymorphism, T cell avidity, and diversity in immune defense

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3538251

Efficient T cell activation requires an optimal dwell-time of interaction between the TCR and the pMHC complex

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3538251

Ligand recognition by alpha beta T cell receptors

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3538251

How the T Cell Repertoire Becomes Peptide and MHC Specific

21 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1208328110

Peptide-MHC potency governs dynamic interactions between T cells and dendritic cells in lymph nodes

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1208328110

Distinct T cell dynamics in lymph nodes during the induction of tolerance and immunity

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1208328110

The impact of duration versus extent of TCR occupancy on T cell activation: a revision of the kinetic proofreading model

21 January 2018

1 reference

12 December 2020

Repeated antigen exposure is necessary for the differentiation, but not the initial proliferation, of naive CD4(+) T cells

1 reference

12 December 2020

Quantitative analysis of the contribution of TCR/pepMHC affinity and CD8 to T cell activation

1 reference

12 December 2020

T cell fitness determined by signal strength

1 reference

12 December 2020

Kinetics and affinity of reactions between an antigen-specific T cell receptor and peptide-MHC complexes

1 reference

12 December 2020

Improved version of a human CD2 minigene based vector for T cell-specific expression in transgenic mice

1 reference

12 December 2020

Induction of IL-4-producing CD4+ T cells by antigenic peptides altered for TCR binding

1 reference

12 December 2020

CD8+ T cell activation is governed by TCR-peptide/MHC affinity, not dissociation rate

1 reference

12 December 2020

High- and low-potency ligands with similar affinities for the TCR: the importance of kinetics in TCR signaling

1 reference

12 December 2020

Clonal selection of helper T cells is determined by an affinity threshold with no further skewing of TCR binding properties

1 reference

12 December 2020

Affinity threshold for thymic selection through a T-cell receptor-co-receptor zipper

1 reference

12 December 2020

Quantitation of lysozyme peptides bound to class II MHC molecules indicates very large differences in levels of presentation

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.1208328110

1 reference

14 August 2017

0 references

1 reference

14 August 2017

1 reference