GSK-3β downregulates Nrf2 in cultured cortical neurons and in a rat model of cerebral ischemia-reperfusion (Q36536328)

14 August 2017

GSK-3β downregulates Nrf2 in cultured cortical neurons and in a rat model of cerebral ischemia-reperfusion (English)

1 reference

14 August 2017

1 reference

Xi Chen

1

1 reference

14 August 2017

Yuanling Liu

2

1 reference

14 August 2017

Jin Zhu

3

1 reference

14 August 2017

Shipeng Lei

4

1 reference

14 August 2017

Yuan Dong

5

1 reference

14 August 2017

Lingyu Li

6

1 reference

14 August 2017

Beibei Jiang

7

1 reference

14 August 2017

Li Tan

8

1 reference

14 August 2017

Jingxian Wu

9

1 reference

14 August 2017

Shanshan Yu

10

1 reference

14 August 2017

Yong Zhao

11

1 reference

14 August 2017

language of work or name

English

0 references

publication date

3 February 2016

1 reference

14 August 2017

1 reference

14 August 2017

6

1 reference

14 August 2017

20196

1 reference

Creative Commons Attribution 4.0 International

14 August 2017

start time

3 February 2016

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Sulforaphane protects primary cultures of cortical neurons against injury induced by oxygen-glucose deprivation/reoxygenation via antiapoptosis

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Nrf2 is controlled by two distinct β-TrCP recognition motifs in its Neh6 domain, one of which can be modulated by GSK-3 activity.

30 September 2017

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Neuroprotection of tanshinone IIA against cerebral ischemia/reperfusion injury through inhibition of macrophage migration inhibitory factor in rats

30 September 2017

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GSK-3 and Wnt Signaling in Neurogenesis and Bipolar Disorder

30 September 2017

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Src subfamily kinases regulate nuclear export and degradation of transcription factor Nrf2 to switch off Nrf2-mediated antioxidant activation of cytoprotective gene expression

30 September 2017

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Targeting Glycogen Synthase Kinase-3β for Therapeutic Benefit against Oxidative Stress in Alzheimer's Disease: Involvement of the Nrf2-ARE Pathway.

30 September 2017

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SCF/{beta}-TrCP promotes glycogen synthase kinase 3-dependent degradation of the Nrf2 transcription factor in a Keap1-independent manner.

30 September 2017

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Tyrosine phosphorylation controls nuclear export of Fyn, allowing Nrf2 activation of cytoprotective gene expression

30 September 2017

1 reference

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Ginsenoside Rb1 protects against 6-hydroxydopamine-induced oxidative stress by increasing heme oxygenase-1 expression through an estrogen receptor-related PI3K/Akt/Nrf2-dependent pathway in human dopaminergic cells.

30 September 2017

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Role of glycogen synthase kinase-3beta in cardioprotection

30 September 2017

1 reference

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Sulforaphane protects astrocytes against oxidative stress and delayed death caused by oxygen and glucose deprivation

30 September 2017

1 reference

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The Nrf2/ARE pathway as a potential therapeutic target in neurodegenerative disease

30 September 2017

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GSK-3beta acts upstream of Fyn kinase in regulation of nuclear export and degradation of NF-E2 related factor 2.

30 September 2017

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Nrf2-Keap1 regulation of cellular defense mechanisms against electrophiles and reactive oxygen species

30 September 2017

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Glycogen synthase kinase-3beta inhibits the xenobiotic and antioxidant cell response by direct phosphorylation and nuclear exclusion of the transcription factor Nrf2.

30 September 2017

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Phosphorylation of tyrosine 568 controls nuclear export of Nrf2.

30 September 2017

1 reference

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Nrf2 signaling in coordinated activation of antioxidant gene expression

30 September 2017

1 reference

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Distinct Cysteine Residues in Keap1 Are Required for Keap1-Dependent Ubiquitination of Nrf2 and for Stabilization of Nrf2 by Chemopreventive Agents and Oxidative Stress

30 September 2017

1 reference

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Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants

30 September 2017

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Functional characterization and role of INrf2 in antioxidant response element-mediated expression and antioxidant induction of NAD(P)H:quinone oxidoreductase1 gene

30 September 2017

1 reference

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Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4738318

Antisense oligonucleotide against GSK-3β in brain of SAMP8 mice improves learning and memory and decreases oxidative stress: Involvement of transcription factor Nrf2 and implications for Alzheimer disease

30 September 2017

1 reference

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Modulation of Ca2+ signals by phosphatidylinositol-linked novel D1 dopamine receptor in hippocampal neurons

28 June 2018

1 reference

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Promotion of dentin regeneration via CCN3 modulation on Notch and BMP signaling pathways

28 June 2018

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Puerarin alleviates cognitive impairment and oxidative stress in APP/PS1 transgenic mice.

21 September 2018

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Signaling pathways activated by the phytochemical nordihydroguaiaretic acid contribute to a Keap1-independent regulation of Nrf2 stability: Role of glycogen synthase kinase-3.

21 September 2018

1 reference

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Apocynum venetum leaf extract protects rat cortical neurons from injury induced by oxygen and glucose deprivation in vitro

21 September 2018

1 reference

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Neuroprotective effect of 4-hydroxybenzyl alcohol against transient focal cerebral ischemia via anti-apoptosis in rats

21 September 2018

1 reference

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Delayed cardioprotection afforded by the glycogen synthase kinase 3 inhibitor SB-216763 occurs via a KATP- and MPTP-dependent mechanism at reperfusion

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4738318

GSK-3beta down-regulates the transcription factor Nrf2 after oxidant damage: relevance to exposure of neuronal cells to oxidative stress.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4738318

Bradykinin prevents reperfusion injury by targeting mitochondrial permeability transition pore through glycogen synthase kinase 3beta

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4738318

Opioid-induced cardioprotection occurs via glycogen synthase kinase beta inhibition during reperfusion in intact rat hearts

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4738318

Preconditioning of cortical neurons by oxygen-glucose deprivation: tolerance induction through abbreviated neurotoxic signaling

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4738318

N6-(3-iodobenzyl)-adenosine-5'-N-methylcarboxamide confers cardioprotection at reperfusion by inhibiting mitochondrial permeability transition pore opening via glycogen synthase kinase 3 beta

21 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26838164

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Mechanisms of ischemic brain damage

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26838164

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Icariside II enhances Nrf2 nuclear translocation to upregulate phase II detoxifying enzyme expression coupled with the ERK, Akt and JNK signaling pathways

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26838164

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/SREP20196

1 reference

14 August 2017

1 reference

14 August 2017

PubMed publication ID

26838164

1 reference