Saccharomyces cerevisiae MutLalpha is a mismatch repair endonuclease (Q36549257)

14 August 2017

Saccharomyces cerevisiae MutLalpha is a mismatch repair endonuclease (English)

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14 August 2017

Saccharomyces cerevisiae

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Farid A Kadyrov

1

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14 August 2017

Shannon F Holmes

2

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14 August 2017

Mercedes E Arana

3

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14 August 2017

Olga A Lukianova

4

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14 August 2017

Mike O'Donnell

5

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14 August 2017

Thomas A Kunkel

6

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14 August 2017

Paul Modrich

7

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14 August 2017

language of work or name

English

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publication date

19 October 2007

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Journal of Biological Chemistry

14 August 2017

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14 August 2017

282

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14 August 2017

51

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14 August 2017

37181-37190

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Mutations affecting a putative MutLalpha endonuclease motif impact multiple mismatch repair functions

14 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2302834

The E705K mutation in hPMS2 exerts recessive, not dominant, effects on mismatch repair

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2302834

Mechanisms in eukaryotic mismatch repair

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2302834

The delitto perfetto approach to in vivo site-directed mutagenesis and chromosome rearrangements with synthetic oligonucleotides in yeast

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2302834

The multifaceted mismatch-repair system

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2302834

DNA mismatch repair: functions and mechanisms

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2302834

Human mismatch repair: reconstitution of a nick-directed bidirectional reaction

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2302834

Reconstitution of 5'-directed human mismatch repair in a purified system

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2302834

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2302834

A defined human system that supports bidirectional mismatch-provoked excision

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2302834

Characterization of human exonuclease 1 in complex with mismatch repair proteins, subcellular localization and association with PCNA

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2302834

Mechanism of 5'-directed excision in human mismatch repair

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2302834

Recognition and repair of the cyclobutane thymine dimer, a major cause of skin cancers, by the human excision nuclease

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2302834

Differential ATP binding and intrinsic ATP hydrolysis by amino-terminal domains of the yeast Mlh1 and Pms1 proteins

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2302834

In vivo requirement for RecJ, ExoVII, ExoI, and ExoX in methyl-directed mismatch repair

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2302834

Mutator phenotypes conferred by MLH1 overexpression and by heterozygosity for mlh1 mutations.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2302834

Mutator phenotypes of yeast strains heterozygous for mutations in the MSH2 gene.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2302834

Hypermutability of homonucleotide runs in mismatch repair and DNA polymerase proofreading yeast mutants.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2302834

Requirement for PCNA in DNA mismatch repair at a step preceding DNA resynthesis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2302834

Mismatch repair in replication fidelity, genetic recombination, and cancer biology

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2302834

Human strand-specific mismatch repair occurs by a bidirectional mechanism similar to that of the bacterial reaction

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2302834

Methyl-directed mismatch repair is bidirectional

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2302834

A mutational analysis of the yeast proliferating cell nuclear antigen indicates distinct roles in DNA replication and DNA repair

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2302834

DNA mismatch correction in a defined system

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2302834

Three-dimensional structure of the beta subunit of E. coli DNA polymerase III holoenzyme: a sliding DNA clamp

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2302834

GATC sequences, DNA nicks and the MutH function in Escherichia coli mismatch repair

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2302834

Purification of eukaryotic MutL homologs from Saccharomyces cerevisiae using self-affinity technology.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2302834

The internal workings of a DNA polymerase clamp-loading machine

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2302834

Assembly of a chromosomal replication machine: two DNA polymerases, a clamp loader, and sliding clamps in one holoenzyme particle. III. Interface between two polymerases and the clamp loader

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2302834

Mispair specificity of methyl-directed DNA mismatch correction in vitro

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2302834

Endonucleolytic function of MutLalpha in human mismatch repair.

28 June 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707617200

Distinct MutS DNA-binding modes that are differentially modulated by ATP binding and hydrolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707617200

Overproduction and analysis of eukaryotic multiprotein complexes in Escherichia coli using a dual-vector strategy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707617200

DNA chain length dependence of formation and dynamics of hMutSalpha.hMutLalpha.heteroduplex complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707617200

Heterologous URA3MX cassettes for gene replacement in Saccharomyces cerevisiae.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707617200

In vivo site-directed mutagenesis using oligonucleotides

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707617200

Drastic genetic instability of tumors and normal tissues in Turcot syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707617200

The MutL ATPase is required for mismatch repair

21 January 2018

1 reference

12 December 2020

Redundant exonuclease involvement in Escherichia coli methyl-directed mismatch repair

1 reference

12 December 2020

Initiation of methyl-directed mismatch repair

1 reference

12 December 2020

Overexpression, purification, DNA binding, and dimerization of the Escherichia coli uvrD gene product (helicase II)

1 reference

12 December 2020

Analysis of interactions between mismatch repair initiation factors and the replication processivity factor PCNA

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M707617200

1 reference

14 August 2017

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14 August 2017

1 reference