Dual immunoregulatory pathways of 4-1BB signaling (Q36573413)

15 August 2017

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title

Dual immunoregulatory pathways of 4-1BB signaling (English)

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15 August 2017

Dass S Vinay

1

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PubMed ID

16924475

15 August 2017

Kiweon Cha

series ordinal

2

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PubMed ID

16924475

15 August 2017

Byoung S Kwon

series ordinal

3

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15 August 2017

5 August 2006

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Journal of Molecular Medicine

15 August 2017

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15 August 2017

84

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15 August 2017

9

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15 August 2017

726-736

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https://scigraph.springernature.com/pub.10.1007/s00109-006-0072-2

15 August 2017

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Serum concentrations of soluble 4-1BB and 4-1BB ligand correlated with the disease severity in rheumatoid arthritis.

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Tumor Expression of 4-1BB Ligand Sustains Tumor Lytic T Cells

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Immune responses in 4-1BB (CD137)-deficient mice

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Cutting edge: Expression of functional CD137 receptor by dendritic cells

21 January 2018

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CD137-deficient mice have reduced NK/NKT cell numbers and function, are resistant to lipopolysaccharide-induced shock syndromes, and have lower IL-4 responses

21 January 2018

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CD137 costimulatory T cell receptor engagement reverses acute disease in lupus-prone NZB x NZW F1 mice

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Regulation of follicular dendritic cell networks by activated T cells: the role of CD137 signaling.

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A switch in costimulation from CD28 to 4-1BB during primary versus secondary CD8 T cell response to influenza in vivo.

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Immunotherapy targeting 4-1BB and its ligand

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Functional expression of 4-1BB (CD137) in the inflammatory tissue in Crohn's disease

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12 December 2020

Expression of 4-1BB molecule on peripheral blood T cells in liver transplanted patients and its clinical implication

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12 December 2020

4-1BB-dependent inhibition of immunosuppression by activated CD4+CD25+ T cells

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12 December 2020

Anti-4-1BB-based immunotherapy for autoimmune diabetes: lessons from a transgenic non-obese diabetic (NOD) model

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12 December 2020

A receptor induced by lymphocyte activation (ILA): a new member of the human nerve-growth-factor/tumor-necrosis-factor receptor family

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Anti-4-1BB monoclonal antibodies abrogate T cell-dependent humoral immune responses in vivo through the induction of helper T cell anergy

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12 December 2020

IDO expression by dendritic cells: tolerance and tryptophan catabolism

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12 December 2020

Improving efficacy of interleukin-12-transfected dendritic cells injected into murine colon cancer with anti-CD137 monoclonal antibodies and alloantigens.

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12 December 2020

4-1BB-like molecule is expressed in islet-infiltrating mononuclear cells and in the gray matter of the brain.

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12 December 2020

TRANCE (tumor necrosis factor [TNF]-related activation-induced cytokine), a new TNF family member predominantly expressed in T cells, is a dendritic cell-specific survival factor

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12 December 2020

CD137 (ILA/4-1BB), expressed by primary human monocytes, induces monocyte activation and apoptosis of B lymphocytes

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12 December 2020

Expression of co-stimulator 4-1BB molecule in hepatocellular carcinoma and adjacent non-tumor liver tissue, and its possible role in tumor immunity

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12 December 2020

The systemic administration of Ig-4-1BB ligand in combination with IL-12 gene transfer eradicates hepatic colon carcinoma

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12 December 2020

CD137 activation abrogates granulocyte-macrophage colony-stimulating factor-mediated anti-apoptosis in neutrophils

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12 December 2020

4-1BB costimulation enhances HSV-1-specific CD8+ T cell responses by the induction of CD11c+CD8+ T cells.

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12 December 2020

The 4-1BB costimulation augments the proliferation of CD4+CD25+ regulatory T cells

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cDNA sequences of two inducible T-cell genes

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Role of T cell costimulation in anti-viral immunity

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Cutting edge: 4-1BB is a bona fide CD8 T cell survival signal

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Regulation of mucosal dendritic cell function by receptor activator of NF-kappa B (RANK)/RANK ligand interactions: impact on tolerance induction

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Monoclonal antibodies against the 4-1BB T-cell activation molecule eradicate established tumors

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Dendritic cells as adjuvants for immune-mediated resistance to tumors

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12 December 2020

Administration of agonistic anti-4-1BB monoclonal antibody leads to the amelioration of experimental autoimmune encephalomyelitis

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12 December 2020

Induction of 4-1BB (CD137) expression by DNA damaging agents in human T lymphocytes

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12 December 2020

New insights into the role of 4-1BB in immune responses: beyond CD8+ T cells

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12 December 2020

Stimulation with 4-1BB (CD137) inhibits chronic graft-versus-host disease by inducing activation-induced cell death of donor CD4+ T cells

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12 December 2020

Dendritic cell-based therapeutics for breast cancer

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12 December 2020

Co-stimulatory members of the TNFR family: keys to effective T-cell immunity?

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12 December 2020

Costimulatory molecule-targeted antibody therapy of a spontaneous autoimmune disease

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12 December 2020

NK1.1 cells express 4-1BB (CDw137) costimulatory molecule and are required for tumor immunity elicited by anti-4-1BB monoclonal antibodies.

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12 December 2020

Monoclonal antibodies directed against the T-cell activation molecule CD137 (interleukin-A or 4-1BB) block human lymphocyte-mediated suppression of tumor xenografts in severe combined immunodeficient mice

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12 December 2020

Costimulation of T cells by OX40, 4-1BB, and CD27.

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12 December 2020

Inducible T cell antigen 4-1BB. Analysis of expression and function

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A humanized anti--4-1BB monoclonal antibody suppresses antigen-induced humoral immune response in nonhuman primates

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4-1BB-mediated immunotherapy of rheumatoid arthritis.

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12 December 2020

Enhancement of CD4 and CD8 immunity by anti-CD137 (4-1BB) monoclonal antibodies during hepatitis C vaccination with recombinant adenovirus

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Gene therapy for cancer using single-chain Fv fragments specific for 4-1BB.

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12 December 2020

ILA, the human 4-1BB homologue, is inducible in lymphoid and other cell lineages

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12 December 2020

Tolerance, DCs and tryptophan: much ado about IDO

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12 December 2020

The B7 family revisited

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12 December 2020

A novel dendritic cell subset involved in tumor immunosurveillance

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12 December 2020

Increased gene expression of tumor necrosis factor superfamily ligands in peripheral blood mononuclear cells during chronic heart failure

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12 December 2020

4-1BB costimulatory signals preferentially induce CD8+ T cell proliferation and lead to the amplification in vivo of cytotoxic T cell responses

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12 December 2020

Immunity to melanoma mediated by 4-1BB is associated with enhanced activity of tumour-infiltrating lymphocytes

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12 December 2020

Isolation and initial characterization of multiple species of T-lymphocyte subset cDNA clones

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12 December 2020

TNF/TNFR family members in costimulation of T cell responses

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12 December 2020

Anti-CD137 monoclonal antibody administration augments the antitumor efficacy of dendritic cell-based vaccines

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12 December 2020

NF-kappaB and AP-1 regulate activation-dependent CD137 (4-1BB) expression in T cells

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12 December 2020

Analysis of 4-1BB ligand (4-1BBL)-deficient mice and of mice lacking both 4-1BBL and CD28 reveals a role for 4-1BBL in skin allograft rejection and in the cytotoxic T cell response to influenza virus.

1 reference

12 December 2020

Thyroid hormone induces the expression of 4-1BB and activation of caspases in a thyroid hormone receptor-dependent manner

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12 December 2020

In vivo stimulation of CD137 broadens primary antiviral CD8+ T cell responses

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12 December 2020

Signaling through NK cell-associated CD137 promotes both helper function for CD8+ cytolytic T cells and responsiveness to IL-2 but not cytolytic activity

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12 December 2020

CD4(+)CD25(+) immunoregulatory T cells: gene expression analysis reveals a functional role for the glucocorticoid-induced TNF receptor

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12 December 2020

Ex vivo expansion of polyclonal and antigen-specific cytotoxic T lymphocytes by artificial APCs expressing ligands for the T-cell receptor, CD28 and 4-1BB.

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12 December 2020

CD40L blockade prevents autoimmune diabetes by induction of bitypic NK/DC regulatory cells

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12 December 2020

4-1BB is expressed on CD45RAhiROhi transitional T cell in humans.

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12 December 2020

Interferon-producing killer dendritic cells provide a link between innate and adaptive immunity

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12 December 2020

In vitro antiinflammatory activity of kalopanaxsaponin A isolated from Kalopanax pictus in murine macrophage RAW 264.7 cells

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12 April 2024

https://opencitations.net/index/api/v1/citations/10.1248/BPB.25.472

Identifiers

DOI

10.1007/S00109-006-0072-2

1 reference

15 August 2017

1 reference

PubMed ID

16924475