Polyfunctional analysis of human t cell responses: importance in vaccine immunogenicity and natural infection (Q36577650)

15 August 2017

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title

Polyfunctional analysis of human t cell responses: importance in vaccine immunogenicity and natural infection (English)

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15 August 2017

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2

Michael R Betts

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15 August 2017

George Makedonas

1

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15 August 2017

25 August 2006

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Seminars in Immunopathology

15 August 2017

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15 August 2017

28

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15 August 2017

209-219

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15 August 2017

3

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https://scigraph.springernature.com/pub.10.1007/s00281-006-0025-4

15 August 2017

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NF-kappaB activation by double-stranded-RNA-activated protein kinase (PKR) is mediated through NF-kappaB-inducing kinase and IkappaB kinase

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HIV nonprogressors preferentially maintain highly functional HIV-specific CD8+ T cells

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CD4+ T cells are required to sustain CD8+ cytotoxic T-cell responses during chronic viral infection

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An N-glycan within the human immunodeficiency virus type 1 gp120 V3 loop affects virus neutralization

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Hierarchical targeting of subtype C human immunodeficiency virus type 1 proteins by CD8+ T cells: correlation with viral load

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Cytokines increase transporter in antigen processing-1 expression more rapidly than HLA class I expression in endothelial cells

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Positive selection of HIV-1 cytotoxic T lymphocyte escape variants during primary infection

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12 December 2020

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12 December 2020

Characterization of functional and phenotypic changes in anti-Gag vaccine-induced T cell responses and their role in protection after HIV-1 infection

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

CD4-deficient mice have reduced levels of memory cytotoxic T lymphocytes after immunization and show diminished resistance to subsequent virus challenge.

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12 December 2020

Viral persistence alters CD8 T-cell immunodominance and tissue distribution and results in distinct stages of functional impairment

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12 December 2020

Viral Clearance Without Destruction of Infected Cells During Acute HBV Infection

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12 December 2020

The tumor necrosis factor ligand and receptor families.

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12 December 2020

Identifying epitopes of HIV-1 that induce protective antibodies

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12 December 2020

Interferon-gamma enhances expression of cellular receptors for tumor necrosis factor

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Vaccinia, cowpox, and camelpox viruses encode soluble gamma interferon receptors with novel broad species specificity

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12 December 2020

An endotoxin-induced serum factor that causes necrosis of tumors

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12 December 2020

Lysis of CD4+ T cells expressing HIV-1 gag peptides by gag-specific CD8+ cytotoxic T cells

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12 December 2020

Cytotoxic T lymphocyte granules are secretory lysosomes, containing both perforin and granzymes

1 reference

12 December 2020

Virus-specific and bystander CD8+ T-cell proliferation in the acute and persistent phases of a gammaherpesvirus infection

1 reference

12 December 2020

Immune response in mice that lack the interferon-gamma receptor

1 reference

12 December 2020

HIV-specific CD8+ T cell proliferation is coupled to perforin expression and is maintained in nonprogressors

1 reference

12 December 2020

A role for the proteasome regulator PA28alpha in antigen presentation

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12 December 2020

Distribution and functional analysis of memory antiviral CD8 T cell responses in HIV-1 and cytomegalovirus infections.

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12 December 2020

HIV-1 evades antibody-mediated neutralization through conformational masking of receptor-binding sites

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12 December 2020

Direct demonstration of cytokine synthesis heterogeneity among human memory/effector T cells by flow cytometry

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12 December 2020

Two subsets of memory T lymphocytes with distinct homing potentials and effector functions

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12 December 2020

Molecular cloning and characterization of the human double-stranded RNA-activated protein kinase induced by interferon

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12 December 2020

Characterization of circulating T cells specific for tumor-associated antigens in melanoma patients

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12 December 2020

Human immunodeficiency virus type 1 replication, immune activation, and circulating cytotoxic T cells against uninfected CD4+ T cells

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12 December 2020

Comprehensive epitope analysis of human immunodeficiency virus type 1 (HIV-1)-specific T-cell responses directed against the entire expressed HIV-1 genome demonstrate broadly directed responses, but no correlation to viral load.

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12 December 2020

Functional impairment of simian immunodeficiency virus-specific CD8+ T cells during the chronic phase of infection

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12 December 2020

HLA B*5701 is highly associated with restriction of virus replication in a subgroup of HIV-infected long term nonprogressors

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12 December 2020

Delay of HIV-1 rebound after cessation of antiretroviral therapy through passive transfer of human neutralizing antibodies

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12 December 2020

Lymphocyte in vitro cytotoxicity: characterization of human lymphotoxin

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12 December 2020

Preferential effect of gamma interferon on the synthesis of HLA antigens and their mRNAs in human cells.

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12 December 2020

The role of cytoplasmic granules in cytotoxicity by large granular lymphocytes and cytotoxic T lymphocytes

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12 December 2020

Sensitive and viable identification of antigen-specific CD8+ T cells by a flow cytometric assay for degranulation

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12 December 2020

HIV-1 viremia prevents the establishment of interleukin 2-producing HIV-specific memory CD4+ T cells endowed with proliferative capacity

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12 December 2020

Late escape from an immunodominant cytotoxic T-lymphocyte response associated with progression to AIDS

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12 December 2020

Interferon-gamma: the major mediator of resistance against Toxoplasma gondii

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12 December 2020

Rapid evolution of the neutralizing antibody response to HIV type 1 infection

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12 December 2020

Influence of combinations of human major histocompatibility complex genes on the course of HIV-1 infection

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12 December 2020

HIV-specific CD8(+) T cells produce antiviral cytokines but are impaired in cytolytic function

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12 December 2020

Intracellular inactivation of the hepatitis B virus by cytotoxic T lymphocytes

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12 December 2020

TNF alpha is an effective therapeutic target for rheumatoid arthritis

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12 December 2020

Diminished Proliferation of Human Immunodeficiency Virus-Specific CD4+T Cells Is Associated with Diminished Interleukin-2 (IL-2) Production and Is Recovered by Exogenous IL-2

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12 December 2020

Quantitation of HIV-1-Specific Cytotoxic T Lymphocytes and Plasma Load of Viral RNA

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12 December 2020

Distinct lineages of T(H)1 cells have differential capacities for memory cell generation in vivo.

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12 December 2020

Tat-specific cytotoxic T lymphocytes select for SIV escape variants during resolution of primary viraemia

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12 December 2020

The activation of IL-2 transcription in L3T4+ and Lyt-2+ lymphocytes during virus infection in vivo.

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12 December 2020

Cytotoxic T-lymphocytes that kill autologous CD4+ lymphocytes are associated with CD4+ lymphocyte depletion in HIV-1 infection

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12 December 2020

Human CD8+ T cells store RANTES in a unique secretory compartment and release it rapidly after TcR stimulation

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12 December 2020

Role of lymphokine-secreting CD8+ T cells in cytotoxic T lymphocyte responses against vaccinia virus

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12 December 2020

10.1007/S00281-006-0025-4

Identifiers

DOI

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15 August 2017

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PubMed ID

16932955