GammaH2AX and its role in DNA double-strand break repair (Q36579390)

15 August 2017

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title

GammaH2AX and its role in DNA double-strand break repair (English)

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15 August 2017

3

Nevan J Krogan

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15 August 2017

Jeffrey Fillingham

1

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PubMed ID

16936829

15 August 2017

Michael-Christopher Keogh

series ordinal

2

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15 August 2017

1 August 2006

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Biochemistry and Cell Biology

15 August 2017

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15 August 2017

84

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15 August 2017

4

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15 August 2017

568-577

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NuA4, an essential transcription adaptor/histone H4 acetyltransferase complex containing Esa1p and the ATM-related cofactor Tra1p

15 August 2017

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Telomeric heterochromatin boundaries require NuA4-dependent acetylation of histone variant H2A.Z in Saccharomyces cerevisiae

21 January 2018

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The ctf13-30/CTF13 genomic haploinsufficiency modifier screen identifies the yeast chromatin remodeling complex RSC, which is required for the establishment of sister chromatid cohesion

21 January 2018

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Increased ionizing radiation sensitivity and genomic instability in the absence of histone H2AX

21 January 2018

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Dynamic assembly and sustained retention of 53BP1 at the sites of DNA damage are controlled by Mdc1/NFBD1

21 January 2018

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Genes required for ionizing radiation resistance in yeast

21 January 2018

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Acetylation of histone H4 by Esa1 is required for DNA double-strand break repair.

21 January 2018

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Tails of histones in DNA double-strand break repair

21 January 2018

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Role of DNA-PK in the cellular response to DNA double-strand breaks

21 January 2018

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ATM phosphorylates histone H2AX in response to DNA double-strand breaks

21 January 2018

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Genomic instability in mice lacking histone H2AX

21 January 2018

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Distinct roles for the RSC and Swi/Snf ATP-dependent chromatin remodelers in DNA double-strand break repair

21 January 2018

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Response to RAG-mediated VDJ cleavage by NBS1 and gamma-H2AX

21 January 2018

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gamma-H2AX dephosphorylation by protein phosphatase 2A facilitates DNA double-strand break repair

21 January 2018

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Protein phosphatase 4--from obscurity to vital functions

21 January 2018

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The proteasome: a utility tool for transcription?

21 January 2018

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How does the histone code work?

21 January 2018

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Nonhomologous end joining in yeast

21 January 2018

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Histone H2AX is phosphorylated at sites of retroviral DNA integration but is dispensable for postintegration repair.

21 January 2018

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Binding of chromatin-modifying activities to phosphorylated histone H2A at DNA damage sites

21 January 2018

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A role for Saccharomyces cerevisiae histone H2A in DNA repair.

21 January 2018

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Chromatin dynamics at DNA replication, transcription and repair

21 January 2018

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Phosphorylation of histone H2B at DNA double-strand breaks.

21 January 2018

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Histone H2A phosphorylation in DNA double-strand break repair

21 January 2018

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Sem1, the yeast ortholog of a human BRCA2-binding protein, is a component of the proteasome regulatory particle that enhances proteasome stability

21 January 2018

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Phosphorylation of histone H2AX and activation of Mre11, Rad50, and Nbs1 in response to replication-dependent DNA double-strand breaks induced by mammalian DNA topoisomerase I cleavage complexes.

21 January 2018

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A novel, evolutionarily conserved protein phosphatase complex involved in cisplatin sensitivity

21 January 2018

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Genome-wide mapping of the cohesin complex in the yeast Saccharomyces cerevisiae

21 January 2018

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Autophosphorylation of ataxia-telangiectasia mutated is regulated by protein phosphatase 2A.

21 January 2018

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Mating-type gene switching in Saccharomyces cerevisiae

21 January 2018

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Global analysis of protein localization in budding yeast

21 January 2018

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Methylated lysine 79 of histone H3 targets 53BP1 to DNA double-strand breaks

21 January 2018

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Sensing and repairing DNA double-strand breaks

21 January 2018

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Translating the Histone Code

21 January 2018

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Chromatin remodeling complexes: ATP-dependent machines in action

21 January 2018

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The DDB1-CUL4ADDB2 ubiquitin ligase is deficient in xeroderma pigmentosum group E and targets histone H2A at UV-damaged DNA sites

21 January 2018

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Nej1p, a cell type-specific regulator of nonhomologous end joining in yeast

21 January 2018

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A phosphatase complex that dephosphorylates gammaH2AX regulates DNA damage checkpoint recovery

21 January 2018

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The Saccharomyces cerevisiae histone H2A variant Htz1 is acetylated by NuA4.

21 January 2018

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A protein complex containing the conserved Swi2/Snf2-related ATPase Swr1p deposits histone variant H2A.Z into euchromatin

21 January 2018

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Maintenance of genome stability in Saccharomyces cerevisiae

21 January 2018

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A Snf2 family ATPase complex required for recruitment of the histone H2A variant Htz1.

21 January 2018

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Regulation of chromosome stability by the histone H2A variant Htz1, the Swr1 chromatin remodeling complex, and the histone acetyltransferase NuA4

21 January 2018

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Proteasome Involvement in the Repair of DNA Double-Strand Breaks

21 January 2018

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Recombination proteins in yeast

21 January 2018

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Acetylation by Tip60 is required for selective histone variant exchange at DNA lesions

21 January 2018

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H2AX: tailoring histone H2A for chromatin-dependent genomic integrity.

21 January 2018

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Instability and decay of the primary structure of DNA

21 January 2018

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Suppression of spontaneous mutagenesis in human cells by DNA base excision-repair

21 January 2018

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Quality control by DNA repair

21 January 2018

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Choreography of the DNA damage response: spatiotemporal relationships among checkpoint and repair proteins

21 January 2018

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Structure and dynamic behavior of nucleosomes

21 January 2018

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Phylogenomics of the nucleosome

21 January 2018

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BRCT Repeats As Phosphopeptide-Binding Modules Involved in Protein Targeting

21 January 2018

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Acetylation of H2AZ Lys 14 is associated with genome-wide gene activity in yeast

21 January 2018

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ATP-driven exchange of histone H2AZ variant catalyzed by SWR1 chromatin remodeling complex

21 January 2018

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Cell cycle and genetic requirements of two pathways of nonhomologous end-joining repair of double-strand breaks in Saccharomyces cerevisiae

21 January 2018

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Histone modifications and DNA double-strand break repair

21 January 2018

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INO80 and gamma-H2AX interaction links ATP-dependent chromatin remodeling to DNA damage repair.

21 January 2018

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DNA-PK phosphorylates histone H2AX during apoptotic DNA fragmentation in mammalian cells

21 January 2018

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Histone acetylation by Trrap-Tip60 modulates loading of repair proteins and repair of DNA double-strand breaks

21 January 2018

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Association of Rad9 with double-strand breaks through a Mec1-dependent mechanism.

21 January 2018

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Histone H2A phosphorylation controls Crb2 recruitment at DNA breaks, maintains checkpoint arrest, and influences DNA repair in fission yeast

21 January 2018

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Segregating sister genomes: the molecular biology of chromosome separation

21 January 2018

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Dephosphorylation of histone gamma-H2AX during repair of DNA double-strand breaks in mammalian cells and its inhibition by calyculin A.

21 January 2018

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Toward maintaining the genome: DNA damage and replication checkpoints

21 January 2018

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AID is required to initiate Nbs1/gamma-H2AX focus formation and mutations at sites of class switching

21 January 2018

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Cellular machineries for chromosomal DNA repair.

21 January 2018

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Histone H2A variants H2AX and H2AZ

21 January 2018

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Yeast histone 2A serine 129 is essential for the efficient repair of checkpoint-blind DNA damage

21 January 2018

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Genetic analysis of Saccharomyces cerevisiae H2A serine 129 mutant suggests a functional relationship between H2A and the sister-chromatid cohesion partners Csm3-Tof1 for the repair of topoisomerase I-induced DNA damage

21 January 2018

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Megabase chromatin domains involved in DNA double-strand breaks in vivo

21 January 2018

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Initiation of DNA fragmentation during apoptosis induces phosphorylation of H2AX histone at serine 139

21 January 2018

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DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139

21 January 2018

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Protein phosphatase 2A in Saccharomyces cerevisiae: effects on cell growth and bud morphogenesis

21 January 2018

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Interfaces between the detection, signaling, and repair of DNA damage

21 January 2018

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Efficient repair of HO-induced chromosomal breaks in Saccharomyces cerevisiae by recombination between flanking homologous sequences

21 January 2018

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Subcellular localization, stoichiometry, and protein levels of 26 S proteasome subunits in yeast

21 January 2018

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A chromatin remodelling complex involved in transcription and DNA processing.

21 January 2018

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The yeast chromatin remodeler RSC complex facilitates end joining repair of DNA double-strand breaks

21 January 2018

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Distribution and dynamics of chromatin modification induced by a defined DNA double-strand break

21 January 2018

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ESA1 is a histone acetyltransferase that is essential for growth in yeast

21 January 2018

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The language of covalent histone modifications

21 January 2018

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Postreplicative recruitment of cohesin to double-strand breaks is required for DNA repair.

21 January 2018

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MDC1 directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks

21 January 2018

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Role of RAD52 epistasis group genes in homologous recombination and double-strand break repair

21 January 2018

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Chromatin in need of a fix: phosphorylation of H2AX connects chromatin to DNA repair

21 January 2018

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Histone H2A phosphorylation and H3 methylation are required for a novel Rad9 DSB repair function following checkpoint activation.

21 January 2018

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Visualization of focal nuclear sites of DNA repair synthesis induced by bleomycin in human cells

21 January 2018

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Chromatin remodelling at a DNA double-strand break site in Saccharomyces cerevisiae

21 January 2018

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DNA damage response pathway uses histone modification to assemble a double-strand break-specific cohesin domain

21 January 2018

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Recruitment of the INO80 complex by H2A phosphorylation links ATP-dependent chromatin remodeling with DNA double-strand break repair

21 January 2018

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Complicated tails: histone modifications and the DNA damage response

21 January 2018

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Histone H2AX is phosphorylated in an ATR-dependent manner in response to replicational stress

21 January 2018

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Accumulation of Checkpoint Protein 53BP1 at DNA Breaks Involves Its Binding to Phosphorylated Histone H2AX

21 January 2018

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Recruitment of the recombinational repair machinery to a DNA double-strand break in yeast

21 January 2018

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DNA repair in a chromatin environment

21 January 2018

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Role of Dot1-dependent histone H3 methylation in G1 and S phase DNA damage checkpoint functions of Rad9.

21 January 2018

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The DNA damage response: putting checkpoints in perspective

21 January 2018

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21 January 2018

Identifiers

DOI

10.1139/O06-072

1 reference

release_5gqbndlx3fcefmprqfrwj2gmey

15 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/5gqbndlx3fcefmprqfrwj2gmey

mapped directly with Wikidata item

24 November 2022

based on heuristic

PubMed ID

16936829

1 reference

PubMed ID

16936829