Notch signaling from the endosome requires a conserved dileucine motif (Q36587968)

15 August 2017

Notch signaling from the endosome requires a conserved dileucine motif (English)

1 reference

15 August 2017

Li Zheng

1

1 reference

15 August 2017

Cosmo A Saunders

2

1 reference

15 August 2017

Erika B Sorensen

3

1 reference

15 August 2017

Nicole C Waxmonsky

4

1 reference

15 August 2017

Sean D Conner

5

1 reference

15 August 2017

21 November 2012

1 reference

Molecular Biology of the Cell

15 August 2017

1 reference

15 August 2017

24

1 reference

15 August 2017

3

1 reference

15 August 2017

297-307

1 reference

describes a project that uses

15 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3564540/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Differential recognition of a dileucine-based sorting signal by AP-1 and AP-3 reveals a requirement for both BLOC-1 and AP-3 in delivery of OCA2 to melanosomes

1 reference

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Metazoan cell biology of the HOPS tethering complex

9 September 2017

1 reference

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Endothelial cell migration on fibronectin is regulated by syntaxin 6-mediated alpha5beta1 integrin recycling

9 September 2017

1 reference

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Molecular mechanism and physiological functions of clathrin-mediated endocytosis

9 September 2017

1 reference

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Clathrin-dependent mechanisms modulate the subcellular distribution of class C Vps/HOPS tether subunits in polarized and nonpolarized cells

9 September 2017

1 reference

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γ-secretase-dependent cleavage initiates notch signaling from the plasma membrane

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564540

Endocytic internalization routes required for delta/notch signaling

9 September 2017

1 reference

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The cell giveth and the cell taketh away: an overview of Notch pathway activation by endocytic trafficking of ligands and receptors

9 September 2017

1 reference

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HOPS interacts with Apl5 at the vacuole membrane and is required for consumption of AP-3 transport vesicles

9 September 2017

1 reference

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Metalloprotease ADAM10 is required for Notch1 site 2 cleavage.

9 September 2017

1 reference

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Numb regulates post-endocytic trafficking and degradation of Notch1.

9 September 2017

1 reference

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The canonical Notch signaling pathway: unfolding the activation mechanism

9 September 2017

1 reference

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9 September 2017

1 reference

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Endosomal entry regulates Notch receptor activation in Drosophila melanogaster

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564540

Phosphatidylinositol-4-kinase type II alpha contains an AP-3-sorting motif and a kinase domain that are both required for endosome traffic

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564540

Regulation of Notch signaling by dynamic changes in the precision of S3 cleavage of Notch-1

9 September 2017

1 reference

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Structural basis for autoinhibition of Notch

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564540

DSL ligand endocytosis physically dissociates Notch1 heterodimers before activating proteolysis can occur

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564540

Lethal giant discs, a novel C2-domain protein, restricts notch activation during endocytosis

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564540

Localization of the AP-3 adaptor complex defines a novel endosomal exit site for lysosomal membrane proteins

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564540

Clathrin-mediated endocytosis in AP-2-depleted cells

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564540

Signals for sorting of transmembrane proteins to endosomes and lysosomes

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564540

Mannose 6-phosphate receptors: new twists in the tale

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564540

Notch signaling in cancer

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564540

Structural requirements for interactions between leucine-sorting signals and clathrin-associated adaptor protein complex AP3

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564540

Insulin-regulated release from the endosomal recycling compartment is regulated by budding of specialized vesicles

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564540

A human protein with sequence similarity to Drosophila mastermind coordinates the nuclear form of notch and a CSL protein to build a transcriptional activator complex on target promoters

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564540

Murine homologs of deltex define a novel gene family involved in vertebrate Notch signaling and neurogenesis

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564540

A novel proteolytic cleavage involved in Notch signaling: the role of the disintegrin-metalloprotease TACE

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564540

Rab7: a key to lysosome biogenesis

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564540

A presenilin-1-dependent gamma-secretase-like protease mediates release of Notch intracellular domain

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564540

Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564540

Human deltex is a conserved regulator of Notch signalling

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564540

Signal transduction by activated mNotch: importance of proteolytic processing and its regulation by the extracellular domain.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564540

The rab7 GTPase resides on a vesicular compartment connected to lysosomes

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564540

Inhibition of rab5 GTPase activity stimulates membrane fusion in endocytosis

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564540

A Role for Acidic Residues in Di-leucine Motif-based Targeting to the Endocytic Pathway

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564540

Signalling downstream of activated mammalian Notch

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564540

Tubular early endosomal networks in AtT20 and other cells

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564540

A novel di-leucine motif and a tyrosine-based motif independently mediate lysosomal targeting and endocytosis of CD3 chains

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564540

Amyloid precursor protein and Notch intracellular domains are generated after transport of their precursors to the cell surface

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564540

SARA, a FYVE domain protein, affects Rab5-mediated endocytosis.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564540

AP-1A and AP-3A lysosomal sorting functions

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564540

Dynamin-dependent transferrin receptor recycling by endosome-derived clathrin-coated vesicles

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564540

Tightly regulated and inducible expression of dominant interfering dynamin mutant in stably transformed HeLa cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564540

Hermansky-Pudlak syndrome protein complexes associate with phosphatidylinositol 4-kinase type II alpha in neuronal and non-neuronal cells.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564540

vps25 mosaics display non-autonomous cell survival and overgrowth, and autonomous apoptosis

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564540

A modified method for lead staining of thin sections.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564540

Movement of internalized ligand-receptor complexes along a continuous endosomal reticulum

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564540

Roles of Drosophila deltex in Notch receptor endocytic trafficking and activation.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564540

Directional Delta and Notch trafficking in Sara endosomes during asymmetric cell division

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564540

Drosophila HOPS and AP-3 complex genes are required for a Deltex-regulated activation of notch in the endosomal trafficking pathway

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564540

The conserved c2 domain protein lethal (2) giant discs regulates protein trafficking in Drosophila

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564540

The first deltex null mutant indicates tissue-specific deltex-dependent Notch signaling in Drosophila

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564540

Tumor suppressor properties of the ESCRT-II complex component Vps25 in Drosophila

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564540

Mutations in erupted, the Drosophila ortholog of mammalian tumor susceptibility gene 101, elicit non-cell-autonomous overgrowth

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564540

The Drosophila tumor suppressor vps25 prevents nonautonomous overproliferation by regulating notch trafficking

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564540

LIN-12/Notch trafficking and regulation of DSL ligand activity during vulval induction in Caenorhabditis elegans

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564540

Drosophila deltex mediates suppressor of Hairless-independent and late-endosomal activation of Notch signaling.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564540

Differential effects of inhibitors on the gamma-secretase complex. Mechanistic implications

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564540

Endocytosis-mediated downregulation of LIN-12/Notch upon Ras activation in Caenorhabditis elegans

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564540

Requirements for presenilin-dependent cleavage of notch and other transmembrane proteins.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564540

Total inactivation of gamma-secretase activity in presenilin-deficient embryonic stem cells.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564540

Implications of dynamic patterns of Delta and Notch expression for cellular interactions during Drosophila development.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564540

Differences in the endosomal distributions of the two mannose 6-phosphate receptors

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564540

Intracellular transport of class II MHC molecules directed by invariant chain.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564540

A ligand-induced extracellular cleavage regulates gamma-secretase-like proteolytic activation of Notch1

20 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23171551

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1091/MBC.E12-02-0081

1 reference

15 August 2017

1 reference

15 August 2017

PubMed publication ID

23171551

1 reference