Narcolepsy and the hypocretin system--where motion meets emotion (Q36600966)

15 August 2017

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title

Narcolepsy and the hypocretin system--where motion meets emotion (English)

1 reference

15 August 2017

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Jerome M Siegel

1

1 reference

PubMed ID

16990828

15 August 2017

Lisa N Boehmer

series ordinal

2

1 reference

15 August 2017

1 October 2006

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Nature Clinical Practice Neurology

15 August 2017

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15 August 2017

2

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15 August 2017

10

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15 August 2017

548-556

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CSF hypocretin/orexin levels in narcolepsy and other neurological conditions.

15 August 2017

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEURO0300

Hypocretin release in normal and narcoleptic dogs after food and sleep deprivation, eating, and movement

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEURO0300

Clinical efficacy of high-dose intravenous immunoglobulins near the onset of narcolepsy in a 10-year-old boy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEURO0300

A mutation in a case of early onset narcolepsy and a generalized absence of hypocretin peptides in human narcoleptic brains

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEURO0300

7 January 2021

Reduced number of hypocretin neurons in human narcolepsy

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEURO0300

7 January 2021

The hypocretins: hypothalamus-specific peptides with neuroexcitatory activity

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEURO0300

7 January 2021

Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEURO0300

7 January 2021

Neurons containing hypocretin (orexin) project to multiple neuronal systems

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEURO0300

7 January 2021

Hypocretin (orexin): role in normal behavior and neuropathology

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEURO0300

7 January 2021

Hypothalamic orexin (hypocretin) neurons express vesicular glutamate transporters VGLUT1 or VGLUT2.

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEURO0300

7 January 2021

Presynaptic and postsynaptic actions and modulation of neuroendocrine neurons by a new hypothalamic peptide, hypocretin/orexin.

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEURO0300

7 January 2021

Excitatory effects of hypocretin-1 (orexin-A) in the trigeminal motor nucleus are reversed by NMDA antagonism

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEURO0300

7 January 2021

Intravenously administered hypocretin-1 alters brain amino acid release: an in vivo microdialysis study in rats

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEURO0300

7 January 2021

Hypocretin/Orexin excites hypocretin neurons via a local glutamate neuron-A potential mechanism for orchestrating the hypothalamic arousal system

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEURO0300

7 January 2021

The wake-promoting hypocretin/orexin neurons change their response to noradrenaline after sleep deprivation.

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEURO0300

7 January 2021

Hypocretin (orexin) deficiency in human narcolepsy.

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEURO0300

7 January 2021

Relationship between CSF hypocretin levels and hypocretin neuronal loss.

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEURO0300

7 January 2021

Narp immunostaining of human hypocretin (orexin) neurons: loss in narcolepsy

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEURO0300

7 January 2021

Concomitant loss of dynorphin, NARP, and orexin in narcolepsy

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEURO0300

7 January 2021

Hypersomnolence and increased REM sleep with low cerebrospinal fluid hypocretin level in a patient after removal of craniopharyngioma.

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEURO0300

7 January 2021

Symptomatic narcolepsy, cataplexy and hypersomnia, and their implications in the hypothalamic hypocretin/orexin system

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEURO0300

7 January 2021

Twin studies in narcolepsy.

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEURO0300

7 January 2021

Complex HLA-DR and -DQ interactions confer risk of narcolepsy-cataplexy in three ethnic groups

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEURO0300

7 January 2021

Autoimmune diseases: the failure of self tolerance

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEURO0300

7 January 2021

Immunohistochemical screening for autoantibodies against lateral hypothalamic neurons in human narcolepsy.

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEURO0300

7 January 2021

Screening for anti-ganglioside antibodies in hypocretin-deficient human narcolepsy

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEURO0300

7 January 2021

Search for neuron-specific and nonneuron-specific antibodies in narcoleptic patients with and without HLA DQB1*0602.

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEURO0300

7 January 2021

Cataplexy-active neurons in the hypothalamus: implications for the role of histamine in sleep and waking behavior

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEURO0300

7 January 2021

Neuronal activity in narcolepsy: identification of cataplexy-related cells in the medial medulla.

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEURO0300

7 January 2021

Locus coeruleus neurons: cessation of activity during cataplexy.

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEURO0300

7 January 2021

Behavioral correlates of activity in identified hypocretin/orexin neurons

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEURO0300

7 January 2021

Expression of a poly-glutamine-ataxin-3 transgene in orexin neurons induces narcolepsy-cataplexy in the rat.

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEURO0300

7 January 2021

Discharge of identified orexin/hypocretin neurons across the sleep-waking cycle.

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEURO0300

7 January 2021

Report of a case of immunosuppression with prednisone in an 8-year-old boy with an acute onset of hypocretin-deficiency narcolepsy

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEURO0300

7 January 2021

Successful management of cataplexy with intravenous immunoglobulins at narcolepsy onset

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEURO0300

7 January 2021

Treatment with immunosuppressive and anti-inflammatory agents delays onset of canine genetic narcolepsy and reduces symptom severity

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEURO0300

7 January 2021

Effects of IV and ICV hypocretin-1 (orexin A) in hypocretin receptor-2 gene mutated narcoleptic dogs and IV hypocretin-1 replacement therapy in a hypocretin-ligand-deficient narcoleptic dog.

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEURO0300

7 January 2021

Pattern of orexin expression and direct biological actions of orexin-a in rat testis

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEURO0300

7 January 2021

Expression of orexin receptors in the brain and peripheral tissues of the male sheep

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEURO0300

7 January 2021

Stimulatory effect of endogenous orexin A on gastric emptying and acid secretion independent of gastrin.

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEURO0300

7 January 2021

Orexin peptides prevent cataplexy and improve wakefulness in an orexin neuron-ablated model of narcolepsy in mice

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEURO0300

7 January 2021

Dopaminergic-adrenergic interactions in the wake promoting mechanism of modafinil

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEURO0300

7 January 2021

Modafinil more effectively induces wakefulness in orexin-null mice than in wild-type littermates

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEURO0300

7 January 2021

Emerging therapies in narcolepsy-cataplexy.

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEURO0300

7 January 2021

Discriminative stimulus effects of GHB and GABA(B) agonists are differentially attenuated by CGP35348.

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEURO0300

7 January 2021

Identifiers

DOI

10.1038/NCPNEURO0300

1 reference

15 August 2017

1 reference

PubMed ID

16990828