Artemis and p53 cooperate to suppress oncogenic N-myc amplification in progenitor B cells. (Q36602126)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14983023%20AND%20SRC:MED&resulttype=core&format=json

24 November 2019

title

Artemis and p53 cooperate to suppress oncogenic N-myc amplification in progenitor B cells (English)

1 reference

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24 November 2019

2

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24 November 2019

author name string

Sean Rooney

1

1 reference

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24 November 2019

Scott Whitlow

3

1 reference

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24 November 2019

Mark Eckersdorff

4

1 reference

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24 November 2019

John P Manis

5

1 reference

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24 November 2019

Charles Lee

6

1 reference

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24 November 2019

David O Ferguson

7

1 reference

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24 November 2019

Frederick W Alt

8

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24 November 2019

language of work or name

English

0 references

publication date

1 February 2004

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14983023%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

24 November 2019

published in

1 reference

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24 November 2019

volume

101

1 reference

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24 November 2019

issue

8

1 reference

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24 November 2019

page(s)

2410-2415

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The role of DNA breaks in genomic instability and tumorigenesis

24 November 2019

cites work

1 reference

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Defective DNA repair and increased genomic instability in Artemis-deficient murine cells

30 September 2017

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Novel Artemis gene mutations of radiosensitive severe combined immunodeficiency in Japanese families

30 September 2017

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Partial T and B lymphocyte immunodeficiency and predisposition to lymphoma in patients with hypomorphic mutations in Artemis

30 September 2017

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Leaky Scid phenotype associated with defective V(D)J coding end processing in Artemis-deficient mice

30 September 2017

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Radiosensitive SCID patients with Artemis gene mutations show a complete B-cell differentiation arrest at the pre-B-cell receptor checkpoint in bone marrow.

30 September 2017

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Evidence for replicative repair of DNA double-strand breaks leading to oncogenic translocation and gene amplification

30 September 2017

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The mechanism and regulation of chromosomal V(D)J recombination

30 September 2017

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Hairpin opening and overhang processing by an Artemis/DNA-dependent protein kinase complex in nonhomologous end joining and V(D)J recombination

30 September 2017

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Ku86 is essential in human somatic cells

30 September 2017

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Artemis, a novel DNA double-strand break repair/V(D)J recombination protein, is mutated in human severe combined immune deficiency.

30 September 2017

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DNA ligase IV deficiency in mice leads to defective neurogenesis and embryonic lethality via the p53 pathway

30 September 2017

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N-myc can functionally replace c-myc in murine development, cellular growth, and differentiation

30 September 2017

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The nonhomologous end-joining pathway of DNA repair is required for genomic stability and the suppression of translocations

30 September 2017

1 reference

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Analysis of ku80-mutant mice and cells with deficient levels of p53

30 September 2017

1 reference

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Interplay of p53 and DNA-repair protein XRCC4 in tumorigenesis, genomic stability and development

30 September 2017

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DNA repair protein Ku80 suppresses chromosomal aberrations and malignant transformation

30 September 2017

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Genetic pathway to recurrent chromosome translocations in murine lymphoma involves V(D)J recombinase

30 September 2017

1 reference

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Ku70: a candidate tumor suppressor gene for murine T cell lymphoma

30 September 2017

1 reference

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No requirement for V(D)J recombination in p53-deficient thymic lymphoma

30 September 2017

1 reference

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Ku70-deficient embryonic stem cells have increased ionizing radiosensitivity, defective DNA end-binding activity, and inability to support V(D)J recombination

30 September 2017

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Tumor spectrum analysis in p53-mutant mice

30 September 2017

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Structure and expression of the murine N-myc gene

30 September 2017

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N-myc transgene promotes B lymphoid proliferation, elicits lymphomas and reveals cross-regulation with c-myc

30 September 2017

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IgH enhancer-mediated deregulation of N-myc gene expression in transgenic mice: generation of lymphoid neoplasias that lack c-myc expression

30 September 2017

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30 September 2017

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Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

30 September 2017

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Mutations in the p53 and SCID genes cooperate in tumorigenesis.

30 September 2017

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Amplified DNA with limited homology to myc cellular oncogene is shared by human neuroblastoma cell lines and a neuroblastoma tumour

28 June 2018

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28 June 2018

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28 June 2018

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Embryonic lethality in mice homozygous for a targeted disruption of the N-myc gene

28 June 2018

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V(D)J recombination activates a p53-dependent DNA damage checkpoint in scid lymphocyte precursors.

28 June 2018

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The RAG-1/2 endonuclease causes genomic instability and controls CNS complications of lymphoblastic leukemia in p53/Prkdc-deficient mice.

21 January 2018

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Unrepaired DNA breaks in p53-deficient cells lead to oncogenic gene amplification subsequent to translocations.

21 January 2018

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Exon skipping caused by an intronic insertion of a young Alu Yb9 element leads to severe hemophilia A.

21 January 2018

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Transposition and amplification of oncogene-related sequences in human neuroblastomas

21 January 2018

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Transgenic N-myc mouse model for indolent B cell lymphoma: tumor characterization and analysis of genetic alterations in spontaneous and retrovirally accelerated tumors.

21 January 2018

1 reference

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Chromosomal location of N-myc and L-myc genes in the mouse

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=356964

Partial T and B lymphocyte immunodeficiency and predisposition to lymphoma in patients with hypomorphic mutations in Artemis

21 October 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0308757101

Characterization of coding ends in thymocytes of scid mice: implications for the mechanism of V(D)J recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0308757101

Histone H2AX: a dosage-dependent suppressor of oncogenic translocations and tumors

21 January 2018

1 reference

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Localization of the 3' IgH locus elements that effect long-distance regulation of class switch recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0308757101

A null c-myc mutation causes lethality before 10.5 days of gestation in homozygotes and reduced fertility in heterozygous female mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0308757101

Enhanced expression of the N-myc gene in Wilms' tumors

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/14983023

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Genetic background alters the spectrum of tumors that develop in p53-deficient mice

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/14983023

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0308757101

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14983023%20AND%20SRC:MED&resulttype=core&format=json

24 November 2019

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14983023%20AND%20SRC:MED&resulttype=core&format=json

24 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14983023%20AND%20SRC:MED&resulttype=core&format=json