P2X(7) receptors: properties and relevance to CNS function (Q36606127)

15 August 2017

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title

P2X(7) receptors: properties and relevance to CNS function (English)

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15 August 2017

Shumin Duan

1

1 reference

PubMed ID

17006902

15 August 2017

Joseph T Neary

series ordinal

2

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PubMed ID

17006902

15 August 2017

language of work or name

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1 November 2006

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15 August 2017

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15 August 2017

54

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15 August 2017

7

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15 August 2017

738-746

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Astrocyte-derived ATP induces vesicle shedding and IL-1 beta release from microglia

15 August 2017

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20397

P2X7 receptors activate protein kinase D and p42/p44 mitogen-activated protein kinase (MAPK) downstream of protein kinase C

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20397

A His-155 to Tyr polymorphism confers gain-of-function to the human P2X7 receptor of human leukemic lymphocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20397

Cutting edge: the nucleotide receptor P2X7 contains multiple protein- and lipid-interaction motifs including a potential binding site for bacterial lipopolysaccharide

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20397

The P2X7 receptor: a key player in IL-1 processing and release

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20397

P2X7 receptor expression after ischemia in the cerebral cortex of rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20397

Mechanisms of P2X7 receptor-mediated ERK1/2 phosphorylation in human astrocytoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20397

Extracellular ATP: effects, sources and fate

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20397

Essential role for Ca2+ in regulation of IL-1beta secretion by P2X7 nucleotide receptor in monocytes, macrophages, and HEK-293 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20397

Potentiation of caspase-1 activation by the P2X7 receptor is dependent on TLR signals and requires NF-kappaB-driven protein synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20397

Regional changes in interstitial K+ and Ca2+ levels following cortical compression contusion trauma in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20397

Molecular physiology of P2X receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20397

P2X7 receptor-dependent blebbing and the activation of Rho-effector kinases, caspases, and IL-1 beta release

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20397

ATP-induced ATP release from astrocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20397

7 January 2021

Phospholipases C and A2 control lysosome-mediated IL-1 beta secretion: Implications for inflammatory processes

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20397

7 January 2021

Activation of presynaptic P2X7-like receptors depresses mossy fiber-CA3 synaptic transmission through p38 mitogen-activated protein kinase.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20397

7 January 2021

Differential co-localisation of the P2X7 receptor subunit with vesicular glutamate transporters VGLUT1 and VGLUT2 in rat CNS.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20397

7 January 2021

A role for mitogen-activated protein kinase(Erk1/2) activation and non-selective pore formation in P2X7 receptor-mediated thymocyte death

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20397

7 January 2021

P2X7 receptor activation in rat brain cultured astrocytes increases the biosynthetic release of cysteinyl leukotrienes

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20397

7 January 2021

Rat astroglial P2Z (P2X7) receptors regulate intracellular calcium and purine release

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20397

7 January 2021

Agonists and antagonists acting at P2X7 receptor.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20397

7 January 2021

Increased Proliferation Rate of Lymphoid Cells Transfected with the P2X7ATP Receptor

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20397

7 January 2021

Oxidized ATP (oATP) attenuates proinflammatory signaling via P2 receptor‐independent mechanisms

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20397

7 January 2021

Expression of the P2X7-receptor subunit in neurons of the rat retina.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20397

7 January 2021

Ten years of protein kinase B signalling: a hard Akt to follow

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20397

7 January 2021

Signaling through P2X7 receptor in human T cells involves p56lck, MAP kinases, and transcription factors AP-1 and NF-kappa B.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20397

7 January 2021

Synaptic P2X7 and oxygen/glucose deprivation in organotypic hippocampal cultures.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20397

7 January 2021

Mammalian MAP kinase signalling cascades

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20397

7 January 2021

Identification and characterization of splice variants of the human P2X7 ATP channel

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20397

7 January 2021

ATP stimulation of P2X(7) receptors activates three different ionic conductances on cultured mouse Schwann cells

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20397

7 January 2021

ATP mediates rapid microglial response to local brain injury in vivo

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20397

7 January 2021

Expression of P2X7 receptor immunoreactivity in distinct subsets of synaptic terminals in the ventral horn of rat lumbar spinal cord

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20397

7 January 2021

Neuronal P2X7 receptors are targeted to presynaptic terminals in the central and peripheral nervous systems

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20397

7 January 2021

Novel data point to a broader mechanism of action of oxidized ATP: the P2X7 receptor is not the only target

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20397

7 January 2021

The P2Z/P2X7 receptor of microglial cells: a novel immunomodulatory receptor.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20397

7 January 2021

Mitogen-activated protein kinase and caspase signaling pathways are required for P2X7 receptor (P2X7R)-induced pore formation in human THP-1 cells

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20397

7 January 2021

P2X7 receptor-mediated release of excitatory amino acids from astrocytes.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20397

7 January 2021

Signal transduction via P2-purinergic receptors for extracellular ATP and other nucleotides

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20397

7 January 2021

Calcium dynamics in the extracellular space of mammalian neural tissue

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20397

7 January 2021

Defining pathways of loss and secretion of chemical messengers from astrocytes

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20397

7 January 2021

ATP-mediated cytotoxicity in microglial cells

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20397

7 January 2021

P2Z purinoreceptor ligation induces activation of caspases with distinct roles in apoptotic and necrotic alterations of cell death

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20397

7 January 2021

Modulation of intercellular communication in macrophages: possible interactions between GAP junctions and P2 receptors

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20397

7 January 2021

P2X(7) receptor-mRNA and -protein in the mouse retina; changes during retinal degeneration in BALBCrds mice

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20397

7 January 2021

VGLUTs define subsets of excitatory neurons and suggest novel roles for glutamate

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20397

7 January 2021

The isoquinoline derivative KN-62 a potent antagonist of the P2Z-receptor of human lymphocytes

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20397

7 January 2021

Permeabilization of transformed mouse fibroblasts by 3'-O-(4-benzoyl)benzoyl adenosine 5'-triphosphate and the desensitization of the process.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20397

7 January 2021

Norepinephrine triggers release of glial ATP to increase postsynaptic efficacy.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20397

7 January 2021

Purinergic receptors are part of a signaling system for keratinocyte proliferation, differentiation, and apoptosis in human fetal epidermis

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20397

7 January 2021

An Arg307 to Gln polymorphism within the ATP-binding site causes loss of function of the human P2X7 receptor.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20397

7 January 2021

A Glu-496 to Ala polymorphism leads to loss of function of the human P2X7 receptor

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20397

7 January 2021

Extracellular ATP triggers tumor necrosis factor-alpha release from rat microglia

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20397

7 January 2021

P2X7-like receptor subunits enhance excitatory synaptic transmission at central synapses by presynaptic mechanisms

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20397

7 January 2021

P2X7 receptors stimulate AKT phosphorylation in astrocytes

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20397

7 January 2021

N-methyl-D-glucamine and propidium dyes utilize different permeation pathways at rat P2X(7) receptors

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20397

7 January 2021

Proteomic and functional evidence for a P2X7 receptor signalling complex

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20397

7 January 2021

Bi-functional effects of ATP/P2 receptor activation on tumor necrosis factor-alpha release in lipopolysaccharide-stimulated astrocytes

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20397

7 January 2021

Distribution of P2X receptors on astrocytes in juvenile rat hippocampus

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20397

7 January 2021

Ecto-nucleotidases and nucleoside transporters mediate activation of adenosine receptors on hippocampal mossy fibers by P2X7 receptor agonist 2'-3'-O-(4-benzoylbenzoyl)-ATP.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20397

7 January 2021

Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20397

7 January 2021

Extracellular ATP and P2X7 receptors in neurodegeneration

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20397

7 January 2021

Large pore formation uniquely associated with P2X7 purinergic receptor channels. Focus on "Are second messengers crucial for opening the pore associated with P2X7 receptor?".

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20397

7 January 2021

Hypertonic stress increases T cell interleukin-2 expression through a mechanism that involves ATP release, P2 receptor, and p38 MAPK activation

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20397

7 January 2021

The cytokine IL-1beta transiently enhances P2X7 receptor expression and function in human astrocytes.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20397

7 January 2021

Cell cycle regulation of astrocytes by extracellular nucleotides and fibroblast growth factor-2

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20397

7 January 2021

The release and uptake of excitatory amino acids

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20397

7 January 2021

P2X7-like receptor activation in astrocytes increases chemokine monocyte chemoattractant protein-1 expression via mitogen-activated protein kinase.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20397

7 January 2021

P2X7 receptors in Müller glial cells from the human retina

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20397

7 January 2021

Lack of ATP-evoked GABA and glutamate release in the hippocampus of P2X7 receptor-/- mice

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20397

7 January 2021

Mechanisms of glutamate release from astrocytes: gap junction "hemichannels", purinergic receptors and exocytotic release.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20397

7 January 2021

Astrocytic purinergic signaling coordinates synaptic networks

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20397

7 January 2021

Characterization of modes of release of amino acids in the ischemic/reperfused rat cerebral cortex

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20397

7 January 2021

Characterization of a functional P2X(7)-like receptor in cerebellar granule neurons from P2X(7) knockout mice

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20397

7 January 2021

Ecto-ADP-ribosyltransferases (ARTs): emerging actors in cell communication and signaling

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20397

7 January 2021

Reanalysis of P2X7 receptor expression in rodent brain

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20397

7 January 2021

Involvement of P2X7 receptors in the regulation of neurotransmitter release in the rat hippocampus

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20397

7 January 2021

Extracellular calcium activity in the injured spinal cord

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20397

7 January 2021

P2X7 receptors mediate ATP release and amplification of astrocytic intercellular Ca2+ signaling

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20397

7 January 2021

The cytolytic P2Z receptor for extracellular ATP identified as a P2X receptor (P2X7)

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20397

7 January 2021

Production and release of neuroprotective tumor necrosis factor by P2X7 receptor-activated microglia.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20397

7 January 2021

Identification of the differentiation-associated Na+/PI transporter as a novel vesicular glutamate transporter expressed in a distinct set of glutamatergic synapses.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20397

7 January 2021

P2X7 receptor inhibition improves recovery after spinal cord injury

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20397

7 January 2021

An Ile-568 to Asn polymorphism prevents normal trafficking and function of the human P2X7 receptor

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20397

7 January 2021

Presynaptic regulation of quantal size by the vesicular glutamate transporter VGLUT1.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20397

7 January 2021

P2X7 receptors control 2-arachidonoylglycerol production by microglial cells

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20397

7 January 2021

Changes in expression of P2X purinoceptors in rat cerebellum during postnatal development

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20397

7 January 2021

Functional hemichannels in astrocytes: a novel mechanism of glutamate release.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20397

7 January 2021

ATP released by astrocytes mediates glutamatergic activity-dependent heterosynaptic suppression

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20397

7 January 2021

Identifiers

DOI

10.1002/GLIA.20397

1 reference

15 August 2017

1 reference

PubMed ID

17006902