Human nonsense-mediated mRNA decay factor UPF2 interacts directly with eRF3 and the SURF complex (Q36627960)

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4 March 2020

title

Human nonsense-mediated mRNA decay factor UPF2 interacts directly with eRF3 and the SURF complex (English)

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4 March 2020

3

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4 March 2020

Oscar Llorca

12

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4 March 2020

author name string

Andrés López-Perrote

1

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4 March 2020

Raquel Castaño

2

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4 March 2020

Teresa Zamarro

4

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4 March 2020

Hitomi Kurosawa

5

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4 March 2020

Tetsuo Ohnishi

6

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4 March 2020

Akiko Uchiyama

7

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4 March 2020

Kyoko Aoyagi

8

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Gretel Buchwald

9

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Naoyuki Kataoka

10

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4 March 2020

Akio Yamashita

11

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4 March 2020

language of work or name

English

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publication date

5 January 2016

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4 March 2020

published in

Nucleic Acids Research

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volume

44

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issue

4

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4 March 2020

page(s)

1909-1923

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Creative Commons Attribution-NonCommercial 4.0 International

4 March 2020

copyright license

start time

6 October 2016

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

Nonsense-Mediated mRNA Decay: Degradation of Defective Transcripts Is Only Part of the Story

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Nonsense-mediated mRNA decay: an intricate machinery that shapes transcriptomes

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A network of SMG-8, SMG-9 and SMG-1 C-terminal insertion domain regulates UPF1 substrate recruitment and phosphorylation

30 September 2017

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Smg6/Est1 licenses embryonic stem cell differentiation via nonsense-mediated mRNA decay

30 September 2017

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A novel phosphorylation-independent interaction between SMG6 and UPF1 is essential for human NMD.

30 September 2017

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Structure of the mammalian ribosomal pre-termination complex associated with eRF1*eRF3*GDPNP

30 September 2017

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Structural and functional analysis of the three MIF4G domains of nonsense-mediated decay factor UPF2

30 September 2017

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Structure and RNA-binding properties of the Not1-Not2-Not5 module of the yeast Ccr4-Not complex

30 September 2017

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Comparison of EJC-enhanced and EJC-independent NMD in human cells reveals two partially redundant degradation pathways

30 September 2017

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Translation-dependent displacement of UPF1 from coding sequences causes its enrichment in 3' UTRs

30 September 2017

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Global analyses of UPF1 binding and function reveal expanded scope of nonsense-mediated mRNA decay

30 September 2017

1 reference

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Nonsense-mediated mRNA decay - mechanisms of substrate mRNA recognition and degradation in mammalian cells

30 September 2017

1 reference

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Rules that govern UPF1 binding to mRNA 3' UTRs

30 September 2017

1 reference

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Role of SMG-1-mediated Upf1 phosphorylation in mammalian nonsense-mediated mRNA decay

30 September 2017

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Structural insights into nonsense-mediated mRNA decay (NMD) by electron microscopy

30 September 2017

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Cryo-EM structure of the mammalian eukaryotic release factor eRF1-eRF3-associated termination complex

30 September 2017

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NMD: a multifaceted response to premature translational termination

30 September 2017

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RELION: implementation of a Bayesian approach to cryo-EM structure determination

30 September 2017

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Human CWC22 escorts the helicase eIF4AIII to spliceosomes and promotes exon junction complex assembly

30 September 2017

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N- and C-terminal Upf1 phosphorylations create binding platforms for SMG-6 and SMG-5:SMG-7 during NMD

30 September 2017

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Molecular mechanisms for the RNA-dependent ATPase activity of Upf1 and its regulation by Upf2

30 September 2017

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The nonsense-mediated mRNA decay SMG-1 kinase is regulated by large-scale conformational changes controlled by SMG-8.

30 September 2017

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Insights into the recruitment of the NMD machinery from the crystal structure of a core EJC-UPF3b complex

30 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4770235

AAA+ proteins RUVBL1 and RUVBL2 coordinate PIKK activity and function in nonsense-mediated mRNA decay

30 September 2017

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Unusual bipartite mode of interaction between the nonsense-mediated decay factors, UPF1 and UPF2

30 September 2017

1 reference

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Structural insights into eRF3 and stop codon recognition by eRF1

30 September 2017

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SMG-8 and SMG-9, two novel subunits of the SMG-1 complex, regulate remodeling of the mRNA surveillance complex during nonsense-mediated mRNA decay

30 September 2017

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Recognition of nonsense mRNA: towards a unified model

30 September 2017

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A competition between stimulators and antagonists of Upf complex recruitment governs human nonsense-mediated mRNA decay

30 September 2017

1 reference

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Posttranscriptional gene regulation by spatial rearrangement of the 3' untranslated region

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4770235

Interactions between UPF1, eRFs, PABP and the exon junction complex suggest an integrated model for mammalian NMD pathways

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4770235

mRNA quality control: an ancient machinery recognizes and degrades mRNAs with nonsense codons.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4770235

An alternative branch of the nonsense-mediated decay pathway

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4770235

Bsoft: image processing and molecular modeling for electron microscopy

30 September 2017

1 reference

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EMAN2: an extensible image processing suite for electron microscopy

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4770235

Binding of a novel SMG-1-Upf1-eRF1-eRF3 complex (SURF) to the exon junction complex triggers Upf1 phosphorylation and nonsense-mediated mRNA decay

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4770235

Involvement of human release factors eRF3a and eRF3b in translation termination and regulation of the termination complex formation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4770235

The structural basis for the interaction between nonsense-mediated mRNA decay factors UPF2 and UPF3

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4770235

A simple whole cell lysate system for in vitro splicing reveals a stepwise assembly of the exon-exon junction complex

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4770235

Role of the nonsense-mediated decay factor hUpf3 in the splicing-dependent exon-exon junction complex

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4770235

Human SMG-1, a novel phosphatidylinositol 3-kinase-related protein kinase, associates with components of the mRNA surveillance complex and is involved in the regulation of nonsense-mediated mRNA decay

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4770235

The role of Upf proteins in modulating the translation read-through of nonsense-containing transcripts

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4770235

Molecular cloning of a novel member of the eukaryotic polypeptide chain-releasing factors (eRF). Its identification as eRF3 interacting with eRF1

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4770235

Relationship between yeast polyribosomes and Upf proteins required for nonsense mRNA decay

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4770235

Structure of a human translation termination complex

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4770235

RNA degradation drives stem cell differentiation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4770235

The cryo-EM structure of the UPF-EJC complex shows UPF1 poised toward the RNA 3' end.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4770235

3-D Structures of Macromolecules Using Single-Particle Analysis in EMAN

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4770235

NMD factors UPF2 and UPF3 bridge UPF1 to the exon junction complex and stimulate its RNA helicase activity

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4770235

3' UTR length and messenger ribonucleoprotein composition determine endocleavage efficiencies at termination codons.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4770235

The RNA helicase DHX34 activates NMD by promoting a transition from the surveillance to the decay-inducing complex

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4770235

Structures of SMG1-UPFs complexes: SMG1 contributes to regulate UPF2-dependent activation of UPF1 in NMD.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4770235

EJC-independent degradation of nonsense immunoglobulin-mu mRNA depends on 3' UTR length.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4770235

Crystal structure and functional analysis of the eukaryotic class II release factor eRF3 from S. pombe

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4770235

20 September 2018

Identifiers

DOI

10.1093/NAR/GKV1527

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26740584%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26740584%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

PubMed publication ID

26740584

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26740584%20AND%20SRC:MED&resulttype=core&format=json