Recent insights into the mechanisms of antifungal resistance (Q36634450)

15 August 2017

Recent insights into the mechanisms of antifungal resistance (English)

1 reference

15 August 2017

Katherine S Barker

1

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PubMed ID

17064638

15 August 2017

P David Rogers

series ordinal

2

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15 August 2017

1 November 2006

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Current infectious disease reports

15 August 2017

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15 August 2017

8

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15 August 2017

6

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15 August 2017

449-456

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The genetic basis of fluconazole resistance development in Candida albicans

15 August 2017

2 references

Crossref

https://api.crossref.org/works/10.1007%2FS11908-006-0019-3

21 January 2018

12 December 2020

A mutation in Tac1p, a transcription factor regulating CDR1 and CDR2, is coupled with loss of heterozygosity at chromosome 5 to mediate antifungal resistance in Candida albicans

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12 December 2020

Multiple cis-acting sequences mediate upregulation of the MDR1 efflux pump in a fluconazole-resistant clinical Candida albicans isolate

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12 December 2020

Proteomic analysis of azole resistance in Candida albicans clinical isolates

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12 December 2020

Emergence of fluconazole-resistant strains of Candida albicans in patients with recurrent oropharyngeal candidosis and human immunodeficiency virus infection.

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12 December 2020

Regulated overexpression of CDR1 in Candida albicans confers multidrug resistance.

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12 December 2020

Inactivation of the FCY2 gene encoding purine-cytosine permease promotes cross-resistance to flucytosine and fluconazole in Candida lusitaniae.

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12 December 2020

PDR16-mediated azole resistance in Candida albicans

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12 December 2020

Clinical, cellular, and molecular factors that contribute to antifungal drug resistance.

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12 December 2020

Genome-wide expression profiling reveals genes associated with amphotericin B and fluconazole resistance in experimentally induced antifungal resistant isolates of Candida albicans

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12 December 2020

Mechanism of increased fluconazole resistance in Candida glabrata during prophylaxis

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12 December 2020

Molecular mechanisms of primary resistance to flucytosine in Candida albicans

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12 December 2020

An update on antifungal targets and mechanisms of resistance in Candida albicans

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12 December 2020

Isolation and characterization of fluconazole- and amphotericin B-resistant Candida albicans from blood of two patients with leukemia

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12 December 2020

Resistance to fluconazole and cross-resistance to amphotericin B in Candida albicans from AIDS patients caused by defective sterol delta5,6-desaturation

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12 December 2020

Multiple patterns of resistance to fluconazole in Candida glabrata isolates from a patient with oropharyngeal candidiasis receiving head and neck radiation

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12 December 2020

Amphotericin B and caspofungin resistance in Candida glabrata isolates recovered from a critically ill patient

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12 December 2020

Pdr1 regulates multidrug resistance in Candida glabrata: gene disruption and genome-wide expression studies.

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12 December 2020

Molecular mechanisms of fluconazole resistance in Candida dubliniensis isolates from human immunodeficiency virus-infected patients with oropharyngeal candidiasis

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12 December 2020

Role of Candida albicans transcription factor Upc2p in drug resistance and sterol metabolism

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12 December 2020

Disruption of ergosterol biosynthesis confers resistance to amphotericin B in Candida lusitaniae

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12 December 2020

Genome-wide expression profile analysis reveals coordinately regulated genes associated with stepwise acquisition of azole resistance in Candida albicans clinical isolates

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12 December 2020

Candida albicans zinc cluster protein Upc2p confers resistance to antifungal drugs and is an activator of ergosterol biosynthetic genes

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12 December 2020

Distinct patterns of gene expression associated with development of fluconazole resistance in serial candida albicans isolates from human immunodeficiency virus-infected patients with oropharyngeal candidiasis

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12 December 2020

Disseminated paracoccidioidomycosis: correlation between clinical and in vitro resistance to ketoconazole and trimethoprim sulphamethoxazole

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12 December 2020

Clade-specific flucytosine resistance is due to a single nucleotide change in the FUR1 gene of Candida albicans

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12 December 2020

Emergence of resistance to fluconazole as a cause of failure during treatment of histoplasmosis in patients with acquired immunodeficiency disease syndrome

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12 December 2020

Flucytosine: a review of its pharmacology, clinical indications, pharmacokinetics, toxicity and drug interactions

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12 December 2020

Genome-wide expression profiling of the response to polyene, pyrimidine, azole, and echinocandin antifungal agents in Saccharomyces cerevisiae

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12 December 2020

Acquired itraconazole resistance in Aspergillus fumigatus

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12 December 2020

A common drug-responsive element mediates the upregulation of the Candida albicans ABC transporters CDR1 and CDR2, two genes involved in antifungal drug resistance

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12 December 2020

Candida glabrata PDR1, a transcriptional regulator of a pleiotropic drug resistance network, mediates azole resistance in clinical isolates and petite mutants

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12 December 2020

MDR1-mediated drug resistance in Candida dubliniensis

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12 December 2020

Caspofungin resistance in Candida albicans: correlating clinical outcome with laboratory susceptibility testing of three isogenic isolates serially obtained from a patient with progressive Candida esophagitis

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12 December 2020

Candida albicans mutations in the ergosterol biosynthetic pathway and resistance to several antifungal agents

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12 December 2020

Drug-induced regulation of the MDR1 promoter in Candida albicans

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12 December 2020

A proteomic approach to understanding the development of multidrug-resistant Candida albicans strains

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12 December 2020

The ATP binding cassette transporter gene CgCDR1 from Candida glabrata is involved in the resistance of clinical isolates to azole antifungal agents.

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12 December 2020

Overexpression of Candida albicans CDR1, CDR2, or MDR1 does not produce significant changes in echinocandin susceptibility

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12 December 2020

Specific substitutions in the echinocandin target Fks1p account for reduced susceptibility of rare laboratory and clinical Candida sp. isolates

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12 December 2020

The Candida albicans Cdr2p ATP-binding cassette (ABC) transporter confers resistance to caspofungin.

1 reference

12 December 2020

Molecular mechanisms of itraconazole resistance in Candida dubliniensis

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12 December 2020

Azole resistance in Candida glabrata: coordinate upregulation of multidrug transporters and evidence for a Pdr1-like transcription factor

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12 December 2020

TAC1, transcriptional activator of CDR genes, is a new transcription factor involved in the regulation of Candida albicans ABC transporters CDR1 and CDR2.

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12 December 2020

Activation of the multiple drug resistance gene MDR1 in fluconazole-resistant, clinical Candida albicans strains is caused by mutations in a trans-regulatory factor

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12 December 2020

Overexpression of the MDR1 gene is sufficient to confer increased resistance to toxic compounds in Candida albicans

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12 December 2020

10.1007/S11908-006-0019-3

Identifiers

DOI

1 reference

15 August 2017

1 reference

PubMed ID

17064638