Linking the metabolic state and mitochondrial DNA in chronic disease, health, and aging (Q36635352)

15 August 2017

Linking the metabolic state and mitochondrial DNA in chronic disease, health, and aging (English)

1 reference

15 August 2017

0 references

Martin Picard

1

1 reference

PMCID

3581215

15 August 2017

Doug M Turnbull

series ordinal

2

1 reference

PMCID

3581215

15 August 2017

language of work or name

English

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publication date

1 March 2013

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15 August 2017

7

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inferred from page(s)

published in

Diabetes

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15 August 2017

62

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15 August 2017

672-678

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15 August 2017

3

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Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported

15 August 2017

start time

27 August 2021

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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Mitochondrial fission, fusion, and stress

30 September 2017

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Impact of caloric restriction on health and survival in rhesus monkeys from the NIA study

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Mitochondrial dynamics and autophagy aid in removal of persistent mitochondrial DNA damage in Caenorhabditis elegans

30 September 2017

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Toward a unifying hypothesis of metabolic syndrome.

30 September 2017

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Exercise-induced BCL2-regulated autophagy is required for muscle glucose homeostasis

30 September 2017

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Diabetic retinopathy and damage to mitochondrial structure and transport machinery

30 September 2017

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Pathways to aging: the mitochondrion at the intersection of biological and psychosocial sciences.

30 September 2017

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Altered mitochondrial dynamics contributes to endothelial dysfunction in diabetes mellitus

30 September 2017

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Mitochondrial aging is accelerated by anti-retroviral therapy through the clonal expansion of mtDNA mutations

30 September 2017

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Reversal of type 2 diabetes: normalisation of beta cell function in association with decreased pancreas and liver triacylglycerol.

30 September 2017

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Tubular network formation protects mitochondria from autophagosomal degradation during nutrient starvation

30 September 2017

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During autophagy mitochondria elongate, are spared from degradation and sustain cell viability.

30 September 2017

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Endurance exercise rescues progeroid aging and induces systemic mitochondrial rejuvenation in mtDNA mutator mice

30 September 2017

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Diabetes mellitus, fasting glucose, and risk of cause-specific death

30 September 2017

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Telomere dysfunction induces metabolic and mitochondrial compromise.

30 September 2017

1 reference

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Chronically elevated glucose compromises myocardial mitochondrial DNA integrity by alteration of mitochondrial topoisomerase function

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581215

Mitochondrial fusion and fission in cell life and death

30 September 2017

1 reference

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Telomeres, lifestyle, cancer, and aging

30 September 2017

1 reference

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Mitochondria and the culture of the Borg: understanding the integration of mitochondrial function within the reticulum, the cell, and the organism.

30 September 2017

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The power of exercise: buffering the effect of chronic stress on telomere length

30 September 2017

1 reference

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Mitochondrial fusion is required for mtDNA stability in skeletal muscle and tolerance of mtDNA mutations

30 September 2017

1 reference

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Leukocyte telomere length is preserved with aging in endurance exercise-trained adults and related to maximal aerobic capacity

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581215

Metabolic reprogramming, caloric restriction and aging

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581215

Effects of physical activity on cardiovascular and noncardiovascular outcomes in older adults

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581215

Insulin resistance is a cellular antioxidant defense mechanism

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581215

Response of mitochondrial fusion and fission protein gene expression to exercise in rat skeletal muscle

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581215

Caloric restriction delays disease onset and mortality in rhesus monkeys

30 September 2017

1 reference

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Mitochondrial networking protects beta-cells from nutrient-induced apoptosis.

30 September 2017

1 reference

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30 September 2017

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The role of exercise and PGC1alpha in inflammation and chronic disease

30 September 2017

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Mitochondrial fission mediates high glucose-induced cell death through elevated production of reactive oxygen species

30 September 2017

1 reference

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Fission and selective fusion govern mitochondrial segregation and elimination by autophagy

30 September 2017

1 reference

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Role of low energy expenditure and sitting in obesity, metabolic syndrome, type 2 diabetes, and cardiovascular disease

30 September 2017

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Life extension by calorie restriction in humans

30 September 2017

1 reference

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Neuropeptide Y acts directly in the periphery on fat tissue and mediates stress-induced obesity and metabolic syndrome

30 September 2017

1 reference

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Aging, adiposity, and calorie restriction

30 September 2017

1 reference

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Intensive insulin therapy in the medical ICU.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581215

A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: a dawn for evolutionary medicine

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581215

Spontaneously immortalized mouse embryo fibroblasts: growth behavior of wild-type and vimentin-deficient cells in relation to mitochondrial structure and activity

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581215

Mitochondrial DNA mutations, oxidative stress, and apoptosis in mammalian aging

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581215

Mitofusins 1/2 and ERRalpha expression are increased in human skeletal muscle after physical exercise

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581215

A potential decline in life expectancy in the United States in the 21st century

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581215

Hyperglycemic conditions affect shape and Ca2+ homeostasis of mitochondria in endothelial cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581215

The glucose transporter families SGLT and GLUT: molecular basis of normal and aberrant function.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581215

Medical Consequences of Obesity

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581215

Premature ageing in mice expressing defective mitochondrial DNA polymerase

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581215

30 September 2017

Telomeres and telomerase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581215

Mitofusin-2 determines mitochondrial network architecture and mitochondrial metabolism. A novel regulatory mechanism altered in obesity

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581215

Effects of the amount and intensity of exercise on plasma lipoproteins

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581215

Dysfunction of mitochondria in human skeletal muscle in type 2 diabetes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581215

Does oxidative damage to DNA increase with age?

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581215

Metabolic implications of body fat distribution

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581215

Regulating ATP turnover rates over broad dynamic work ranges in skeletal muscles

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581215

Exercise and type 2 diabetes: the American College of Sports Medicine and the American Diabetes Association: joint position statement executive summary

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581215

Aging and high concentrations of glucose potentiate injury to mitochondrial DNA.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581215

Increased prevalence of mitochondrial DNA deletions in skeletal muscle of older individuals with impaired glucose tolerance: possible marker of glycemic stress

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581215

Dysfunctional mitochondrial maintenance: what breaks the circle of life?

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581215

Obesity induces signs of premature cardiac aging in younger patients: the role of mitochondria.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581215

Physical exercise prevents cellular senescence in circulating leukocytes and in the vessel wall.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581215

Non-CpG methylation of the PGC-1alpha promoter through DNMT3B controls mitochondrial density.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581215

Oscillating glucose is more deleterious to endothelial function and oxidative stress than mean glucose in normal and type 2 diabetic patients

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581215

The missing link - lose weight, live longer.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581215

Expression of Mfn2, the Charcot-Marie-Tooth neuropathy type 2A gene, in human skeletal muscle: effects of type 2 diabetes, obesity, weight loss, and the regulatory role of tumor necrosis factor alpha and interleukin-6.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581215

Effect of intermittent fasting and refeeding on insulin action in healthy men.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581215

Protection of hepatocyte mitochondrial ultrastructure and function by strict blood glucose control with insulin in critically ill patients

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581215

Accumulation of somatic mutation in mitochondrial DNA extracted from peripheral blood cells in diabetic patients

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581215

Accumulation of 8-hydroxy-2'-deoxyguanosine and mitochondrial DNA deletion in kidney of diabetic rats

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581215

Low cardiorespiratory fitness and physical inactivity as predictors of mortality in men with type 2 diabetes.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581215

Muscle metabolism during graded quadriceps exercise in man

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581215

Early versus Late Parenteral Nutrition in Critically Ill Adults

21 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581215

Adiposity as Compared with Physical Activity in Predicting Mortality among Women

4 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581215

On mitochondria, mutations, and methodology

4 December 2018

1 reference

12 December 2020

Physical Activity and Life Expectancy With and Without Diabetes: Life table analysis of the Framingham Heart Study

1 reference

12 December 2020

Evidence for a mitochondrial regulatory pathway defined by peroxisome proliferator-activated receptor-gamma coactivator-1 alpha, estrogen-related receptor-alpha, and mitofusin 2

1 reference

12 December 2020

Mitochondria in DRG neurons undergo hyperglycemic mediated injury through Bim, Bax and the fission protein Drp1

1 reference

12 December 2020

Convergence of adipocyte hypertrophy, telomere shortening and hypoadiponectinemia in obese subjects and in patients with type 2 diabetes

1 reference

12 December 2020

Advanced Telomere Shortening in Respiratory Chain Disorders

1 reference

12 December 2020

Human cells are protected from mitochondrial dysfunction by complementation of DNA products in fused mitochondria

1 reference

12 December 2020

Leukocyte telomere length is associated with complications of Type 2 diabetes mellitus

1 reference

12 December 2020

Oxidative damage to mitochondrial DNA and its relationship to diabetic complications

1 reference

12 December 2020

Identifiers

DOI

10.2337/DB12-1203

1 reference

15 August 2017

1 reference

15 August 2017

1 reference

PMCID

3581215