Proteasome dysfunction mediates obesity-induced endoplasmic reticulum stress and insulin resistance in the liver (Q36635369)

15 August 2017

Proteasome dysfunction mediates obesity-induced endoplasmic reticulum stress and insulin resistance in the liver (English)

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15 August 2017

endoplasmic reticulum

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Akihiro Kikuchi

8

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Shigeo Murata

object named as

Shigeo Murata

5

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author name string

Toshiki Otoda

1

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15 August 2017

Toshinari Takamura

2

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15 August 2017

Hirofumi Misu

3

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15 August 2017

Tsuguhito Ota

4

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15 August 2017

Hiroto Hayashi

6

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15 August 2017

Hiroaki Takayama

7

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15 August 2017

Takehiro Kanamori

9

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15 August 2017

Kosuke R Shima

10

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15 August 2017

Fei Lan

11

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15 August 2017

Takashi Takeda

12

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15 August 2017

Seiichiro Kurita

13

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15 August 2017

Kazuhide Ishikura

14

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15 August 2017

Yuki Kita

15

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15 August 2017

Kaito Iwayama

16

1 reference

15 August 2017

Ken-ichiro Kato

17

1 reference

15 August 2017

Masafumi Uno

18

1 reference

15 August 2017

Yumie Takeshita

19

1 reference

15 August 2017

Miyuki Yamamoto

20

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15 August 2017

Kunpei Tokuyama

21

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15 August 2017

Shoichi Iseki

22

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15 August 2017

Keiji Tanaka

23

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15 August 2017

Shuichi Kaneko

24

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15 August 2017

language of work or name

English

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publication date

3 December 2012

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15 August 2017

14

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based on heuristic

inferred from page(s)

published in

Diabetes

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15 August 2017

62

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15 August 2017

3

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15 August 2017

811-824

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Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported

15 August 2017

start time

27 August 2021

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

Polysome profiling in liver identifies dynamic regulation of endoplasmic reticulum translatome by obesity and fasting.

1 reference

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Brown rice and its component, γ-oryzanol, attenuate the preference for high-fat diet by decreasing hypothalamic endoplasmic reticulum stress in mice.

30 September 2017

1 reference

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Endoplasmic reticulum stress inhibits STAT3-dependent suppression of hepatic gluconeogenesis via dephosphorylation and deacetylation.

30 September 2017

1 reference

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Enhancement of proteasomal function protects against cardiac proteinopathy and ischemia/reperfusion injury in mice

30 September 2017

1 reference

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Aberrant lipid metabolism disrupts calcium homeostasis causing liver endoplasmic reticulum stress in obesity

30 September 2017

1 reference

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Regulation of glucose homeostasis through a XBP-1-FoxO1 interaction

30 September 2017

1 reference

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Sodium phenylbutyrate, a drug with known capacity to reduce endoplasmic reticulum stress, partially alleviates lipid-induced insulin resistance and beta-cell dysfunction in humans

30 September 2017

1 reference

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Enhancement of proteasome function by PA28α overexpression protects against oxidative stress.

30 September 2017

1 reference

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A liver-derived secretory protein, selenoprotein P, causes insulin resistance.

30 September 2017

1 reference

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β-cell dysfunctional ERAD/ubiquitin/proteasome system in type 2 diabetes mediated by islet amyloid polypeptide-induced UCH-L1 deficiency

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581221

Immunoproteasomes preserve protein homeostasis upon interferon-induced oxidative stress

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581221

Defective hepatic autophagy in obesity promotes ER stress and causes insulin resistance.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581221

Hyperglycemia impairs proteasome function by methylglyoxal

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581221

Hepatic CYP3A suppression by high concentrations of proteasomal inhibitors: a consequence of endoplasmic reticulum (ER) stress induction, activation of RNA-dependent protein kinase-like ER-bound eukaryotic initiation factor 2alpha (eIF2alpha)-kinase

30 September 2017

1 reference

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Preliminary report: inhibition of cellular proteasome activity by free fatty acids

30 September 2017

1 reference

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Palmitate induces insulin resistance in H4IIEC3 hepatocytes through reactive oxygen species produced by mitochondria

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581221

Regulation of hepatic lipogenesis by the transcription factor XBP1

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581221

Selective versus total insulin resistance: a pathogenic paradox

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581221

Inhibition of apolipoprotein B100 secretion by lipid-induced hepatic endoplasmic reticulum stress in rodents

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581221

Ubiquitin-independent degradation of cell-cycle inhibitors by the REGgamma proteasome

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581221

Genes involved in oxidative phosphorylation are coordinately upregulated with fasting hyperglycaemia in livers of patients with type 2 diabetes.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581221

Autophagy counterbalances endoplasmic reticulum expansion during the unfolded protein response

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581221

Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581221

Essential role of ubiquitin-proteasome system in normal regulation of insulin secretion

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581221

Inflammation, stress, and diabetes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581221

Skp2 inhibits FOXO1 in tumor suppression through ubiquitin-mediated degradation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581221

Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581221

Proteasomal degradation of the FoxO1 transcriptional regulator in cells transformed by the P3k and Akt oncoproteins

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581221

Generation of major histocompatibility complex class I antigens: functional interplay between proteasomes and TPPII.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581221

Proteasome inhibition increases HuR level, restores heat-inducible HSP72 expression and thermotolerance in WI-38 senescent human fibroblasts

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581221

Insulin-induced phosphorylation of FKHR (Foxo1) targets to proteasomal degradation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581221

Transcriptional and translational control in the Mammalian unfolded protein response

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581221

The unfolded protein response in nutrient sensing and differentiation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581221

Immunoproteasome assembly and antigen presentation in mice lacking both PA28alpha and PA28beta.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581221

Kinetic evidences for facilitation of peptide channelling by the proteasome activator PA28.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581221

The 26S proteasome: a molecular machine designed for controlled proteolysis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581221

Hybrid proteasomes. Induction by interferon-gamma and contribution to ATP-dependent proteolysis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581221

Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581221

The proteasome, a novel protease regulated by multiple mechanisms

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581221

Expression and subcellular localization of mouse 20S proteasome activator complex PA28

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581221

UPR pathways combine to prevent hepatic steatosis caused by ER stress-mediated suppression of transcriptional master regulators.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581221

Insulin resistance accelerates muscle protein degradation: Activation of the ubiquitin-proteasome pathway by defects in muscle cell signaling

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581221

Predicting hepatitis B virus-positive metastatic hepatocellular carcinomas using gene expression profiling and supervised machine learning

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581221

Impaired immunoproteasome assembly and immune responses in PA28-/- mice.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581221

The hepatic circadian clock is preserved in a lipid-induced mouse model of non-alcoholic steatohepatitis.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581221

Endoplasmic reticulum stress plays a central role in development of leptin resistance

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581221

Obesity upregulates genes involved in oxidative phosphorylation in livers of diabetic patients

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581221

Increased oxidative stress precedes the onset of high-fat diet-induced insulin resistance and obesity

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581221

Stressed out about obesity and insulin resistance

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581221

Involvement of endoplasmic reticulum stress in insulin resistance and diabetes

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581221

Peroxynitrite alters the catalytic activity of rodent liver proteasome in vitro and in vivo

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581221

Genes for systemic vascular complications are differentially expressed in the livers of type 2 diabetic patients.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581221

Direct demonstration of rapid degradation of nuclear sterol regulatory element-binding proteins by the ubiquitin-proteasome pathway

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581221

Diabetes induces an impairment in the proteolytic activity against oxidized proteins and a heterogeneous effect in nonenzymatic protein modifications in the cytosol of rat liver and kidney

20 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23209186

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Growth retardation in mice lacking the proteasome activator PA28gamma

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23209186

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.2337/DB11-1652

1 reference

15 August 2017

1 reference

15 August 2017

1 reference