HIV-1 infection of mononuclear phagocytic cells: the case for bacterial innate immune deficiency in AIDS. (Q36661976)

15 August 2017

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title

HIV-1 infection of mononuclear phagocytic cells: the case for bacterial innate immune deficiency in AIDS. (English)

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15 August 2017

Mahdad Noursadeghi

1

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author name string

David R Katz

series ordinal

2

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PubMed ID

17123899

15 August 2017

Robert F Miller

series ordinal

3

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15 August 2017

1 December 2006

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Lancet Infectious Diseases

15 August 2017

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15 August 2017

6

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15 August 2017

794-804

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15 August 2017

12

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CD14+ blood monocytes can differentiate into functionally mature CD83+ dendritic cells

15 August 2017

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Dendritic cells and the control of immunity

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HIV-1 subtype and second-receptor use

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7 January 2021

Genotypic and phenotypic characterization of HIV-1 patients with primary infection

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7 January 2021

Shedding of HIV-1 in the genital tract

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7 January 2021

Genetic Restriction of HIV-1 Infection and Progression to AIDS by a Deletion Allele of the CKR5 Structural Gene

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7 January 2021

The role of a mutant CCR5 allele in HIV-1 transmission and disease progression.

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7 January 2021

Resistance to HIV-1 infection in caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene

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7 January 2021

Cellular targets of infection and route of viral dissemination after an intravaginal inoculation of simian immunodeficiency virus into rhesus macaques

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7 January 2021

CCR5 expression correlates with susceptibility of maturing monocytes to human immunodeficiency virus type 1 infection

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7 January 2021

Expression of CCR5 increases during monocyte differentiation and directly mediates macrophage susceptibility to infection by human immunodeficiency virus type 1

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7 January 2021

Regulation of primary HIV-1 isolate replication in dendritic cells.

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7 January 2021

DC-SIGN: escape mechanism for pathogens

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7 January 2021

Mononuclear phagocytes of blood and bone marrow: comparative roles as viral reservoirs in human immunodeficiency virus type 1 infections

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7 January 2021

Analysis of lymphocytes, monocytes, and neutrophils from human immunodeficiency virus (HIV)-infected persons for HIV DNA.

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7 January 2021

Langerhans cells and HIV infection

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7 January 2021

Analysis of human immunodeficiency virus type 1 (HIV-1) variants and levels of infection in dendritic and T cells from symptomatic HIV-1-infected patients

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7 January 2021

Detection of AIDS virus in macrophages in brain tissue from AIDS patients with encephalopathy

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7 January 2021

Identification and quantitation of HIV-1 in the liver of patients with AIDS

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7 January 2021

Infected cells and immune cells in the gastrointestinal tract of AIDS patients. An immunohistochemical study of 127 cases.

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7 January 2021

Macrophages as a source of HIV during opportunistic infections

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7 January 2021

The macrophage in the persistence and pathogenesis of HIV infection

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7 January 2021

Detection of infectious HIV in circulating monocytes from patients on prolonged highly active antiretroviral therapy.

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7 January 2021

Recovery of replication-competent HIV type 1-infected circulating monocytes from individuals receiving antiretroviral therapy

1 reference

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7 January 2021

Monocytes harbour replication-competent, non-latent HIV-1 in patients on highly active antiretroviral therapy.

1 reference

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7 January 2021

Macrophages and HIV infection: therapeutical approaches toward this strategic virus reservoir

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7 January 2021

Pattern recognition receptors: doubling up for the innate immune response

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7 January 2021

Toll-like receptors: critical proteins linking innate and acquired immunity

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7 January 2021

The role of Toll-like receptors and Nod proteins in bacterial infection

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7 January 2021

NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses

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7 January 2021

The plasticity of dendritic cell responses to pathogens and their components

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7 January 2021

Human macrophage activation programs induced by bacterial pathogens

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7 January 2021

Essential role of MD-2 in LPS responsiveness and TLR4 distribution.

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7 January 2021

Lipopolysaccharide-binding protein is required to combat a murine gram-negative bacterial infection

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7 January 2021

Critical Role of Lipopolysaccharide-Binding Protein and CD14 in Immune Responses against Gram-Negative Bacteria

1 reference

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7 January 2021

Cutting edge: TLR2-deficient and MyD88-deficient mice are highly susceptible to Staphylococcus aureus infection

1 reference

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7 January 2021

A Toll-like receptor recognizes bacterial DNA

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7 January 2021

Pyogenic bacterial infections in humans with IRAK-4 deficiency

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7 January 2021

MyD88-dependent but Toll-like receptor 2-independent innate immunity to Listeria: no role for either in macrophage listericidal activity

1 reference

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7 January 2021

Mice lacking myeloid differentiation factor 88 display profound defects in host resistance and immune responses to Mycobacterium avium infection not exhibited by Toll-like receptor 2 (TLR2)- and TLR4-deficient animals

1 reference

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7 January 2021

Severe impairment of interleukin-1 and Toll-like receptor signalling in mice lacking IRAK-4

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7 January 2021

Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract

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7 January 2021

Genetic polymorphisms in sepsis and septic shock: role in prognosis and potential for therapy

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7 January 2021

Single nucleotide polymorphisms of Toll-like receptors and susceptibility to infectious disease

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7 January 2021

Regulation of IL-8 and IL-1beta expression in Crohn's disease associated NOD2/CARD15 mutations

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7 January 2021

New strategies for clinical trials in patients with sepsis and septic shock

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7 January 2021

The interface between innate and adaptive immunity

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7 January 2021

Toll-dependent selection of microbial antigens for presentation by dendritic cells

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7 January 2021

Toll-like receptors control activation of adaptive immune responses

1 reference

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7 January 2021

RICK/Rip2/CARDIAK mediates signalling for receptors of the innate and adaptive immune systems

1 reference

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7 January 2021

Treatment of established asthma in a murine model using CpG oligodeoxynucleotides

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7 January 2021

Endotoxins prevent murine IgE production, T(H)2 immune responses, and development of airway eosinophilia but not airway hyperreactivity

1 reference

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7 January 2021

Hyporesponsiveness to vaccination with Borrelia burgdorferi OspA in humans and in TLR1- and TLR2-deficient mice

1 reference

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7 January 2021

Bacterial lipopolysaccharide activates HIV long terminal repeat through Toll-like receptor 4.

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2806%2970656-9

7 January 2021

Gene expression profiling of host response in models of acute HIV infection

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2806%2970656-9

7 January 2021

HIV-1 Nef mediates post-translational down-regulation and redistribution of the mannose receptor.

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2806%2970656-9

7 January 2021

Disruption of MAP kinase activation and nuclear factor binding to the IL-12 p40 promoter in HIV-infected myeloid cells.

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2806%2970656-9

7 January 2021

HIV type 1 Tat protein inhibits interleukin 12 production by human peripheral blood mononuclear cells.

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2806%2970656-9

7 January 2021

HIV impairs TNF-alpha release in response to Toll-like receptor 4 stimulation in human macrophages in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2806%2970656-9

7 January 2021

Nef induces apoptosis by activating JNK signaling pathway and inhibits NF-kappaB-dependent immune responses in Drosophila

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2806%2970656-9

7 January 2021

HIV-1 protein Vpr suppresses IL-12 production from human monocytes by enhancing glucocorticoid action: potential implications of Vpr coactivator activity for the innate and cellular immunity deficits observed in HIV-1 infection

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2806%2970656-9

7 January 2021

Directed expression of the HIV-1 accessory protein Vpu in Drosophila fat-body cells inhibits Toll-dependent immune responses

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2806%2970656-9

7 January 2021

Human immunodeficiency virus type 1 gp120 induces abnormal maturation and functional alterations of dendritic cells: a novel mechanism for AIDS pathogenesis.

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2806%2970656-9

7 January 2021

Impaired monocyte maturation in response to CpG oligodeoxynucleotide is related to viral RNA levels in human immunodeficiency virus disease and is at least partially mediated by deficiencies in alpha/beta interferon responsiveness and production

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2806%2970656-9

7 January 2021

HIV-infected progressors and long-term non-progressors differ in their capacity to respond to an A-class CpG oligodeoxynucleotide

1 reference

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7 January 2021

The role of Tat in the human immunodeficiency virus life cycle indicates a primary effect on transcriptional elongation

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2806%2970656-9

7 January 2021

Block of Tat-mediated transactivation of tumor necrosis factor beta gene expression by polymeric-TAR decoys

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2806%2970656-9

7 January 2021

HIV-1 Tat promotes monocyte chemoattractant protein-1 secretion followed by transmigration of monocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2806%2970656-9

7 January 2021

Native HIV-1 Tat protein targets monocyte-derived dendritic cells and enhances their maturation, function, and antigen-specific T cell responses

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2806%2970656-9

7 January 2021

HIV-1 Tat reprograms immature dendritic cells to express chemoattractants for activated T cells and macrophages

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2806%2970656-9

7 January 2021

Importance of the nef gene for maintenance of high virus loads and for development of AIDS

1 reference

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7 January 2021

Brief report: absence of intact nef sequences in a long-term survivor with nonprogressive HIV-1 infection

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2806%2970656-9

7 January 2021

Nef induces CD4 endocytosis: requirement for a critical dileucine motif in the membrane-proximal CD4 cytoplasmic domain

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2806%2970656-9

7 January 2021

The human immunodeficiency virus-1 nef gene product: a positive factor for viral infection and replication in primary lymphocytes and macrophages

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2806%2970656-9

7 January 2021

Nef triggers a transcriptional program in T cells imitating single-signal T cell activation and inducing HIV virulence mediators

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2806%2970656-9

7 January 2021

Identification and localization of vpr gene product of human immunodeficiency virus type 1.

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2806%2970656-9

7 January 2021

The human immunodeficiency virus type 1 Vpu protein inhibits NF-kappa B activation by interfering with beta TrCP-mediated degradation of Ikappa B.

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2806%2970656-9

7 January 2021

The human immunodeficiency virus type 1 accessory protein Vpu induces apoptosis by suppressing the nuclear factor kappaB-dependent expression of antiapoptotic factors

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2806%2970656-9

7 January 2021

Serum Vpr regulates productive infection and latency of human immunodeficiency virus type 1

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2806%2970656-9

7 January 2021

Vpr is required for efficient replication of human immunodeficiency virus type-1 in mononuclear phagocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2806%2970656-9

7 January 2021

The human immunodeficiency virus type 2 vpr gene is essential for productive infection of human macrophages

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2806%2970656-9

7 January 2021

The HIV-1 virion-associated protein vpr is a coactivator of the human glucocorticoid receptor

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2806%2970656-9

7 January 2021

The HIV-1 Vpr and glucocorticoid receptor complex is a gain-of-function interaction that prevents the nuclear localization of PARP-1

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2806%2970656-9

7 January 2021

HIV-1 Viral Protein-R (VPR) Protects against Lethal Superantigen Challenge While Maintaining Homeostatic T Cell Levels in Vivo

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2806%2970656-9

7 January 2021

HIV-1 Vpr inhibits the maturation and activation of macrophages and dendritic cells in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2806%2970656-9

7 January 2021

HIV-1 viral protein R compromises cellular immune function in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2806%2970656-9

7 January 2021

HIV-1 envelope gp41 is a potent inhibitor of chemoattractant receptor expression and function in monocytes.

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2806%2970656-9

7 January 2021

Impairment of phagosome-lysosome fusion in HIV-1-infected macrophages

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2806%2970656-9

7 January 2021

HIV-1-infected monocyte-derived dendritic cells do not undergo maturation but can elicit IL-10 production and T cell regulation

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2806%2970656-9

7 January 2021

CpG ODNs treatments of HIV-1 infected patients may cause the decline of transmission in high risk populations - a review, hypothesis and implications.

1 reference

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7 January 2021

Relationship of in vivo and ex vivo levels of TH1 and TH2 cytokines with viremia in HAART patients with and without opportunistic infections

1 reference

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7 January 2021

Monocyte derived dendritic cells from HIV-1 infected individuals partially reconstitute CD4 T-cell responses

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2806%2970656-9

7 January 2021

Dysfunction and infection of freshly isolated blood myeloid and plasmacytoid dendritic cells in patients infected with HIV-1

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2806%2970656-9

7 January 2021

Defective phagocytosis by human monocyte/macrophages following HIV-1 infection: underlying mechanisms and modulation by adjunctive cytokine therapy

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2806%2970656-9

7 January 2021

Inhibition of fungicidal activity of polymorphonuclear leukocytes from HIV-infected patients by interleukin (IL)-4 and IL-10

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2806%2970656-9

7 January 2021

Interleukin-12: a bridge between innate resistance and adaptive immunity with a role in infection and acquired immunodeficiency

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2806%2970656-9

7 January 2021

Restoration of HIV-specific cell-mediated immune responses by interleukin-12 in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2806%2970656-9

7 January 2021

Acute bacterial infections and HIV disease

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2806%2970656-9

7 January 2021

Pneumococcal disease during HIV infection. Epidemiologic, clinical, and immunologic perspectives

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2806%2970656-9

7 January 2021

Increased risk of bacterial pneumonia in HIV-infected intravenous drug users without AIDS.

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2806%2970656-9

7 January 2021

The role of human immunodeficiency virus infection in pneumococcal bacteremia in San Francisco residents

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2806%2970656-9

7 January 2021

Incidence of salmonellosis in patients with AIDS.

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2806%2970656-9

7 January 2021

Pathogens and predictors of fatal septicemia associated with human immunodeficiency virus infection in Ivory Coast, west Africa

1 reference

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7 January 2021

Bacteraemia and mortality among adult medical admissions in Malawi--predominance of non-typhi salmonellae and Streptococcus pneumoniae

1 reference

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7 January 2021

Increased disease burden and antibiotic resistance of bacteria causing severe community-acquired lower respiratory tract infections in human immunodeficiency virus type 1-infected children

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2806%2970656-9

7 January 2021

Sepsis in children with human immunodeficiency virus infection. The Madrid HIV Pediatric Infection Collaborative Study Group.

1 reference

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7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2806%2970656-9

7 January 2021

Pseudomonas aeruginosa bacteremia in patients infected with human immunodeficiency virus type 1.

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2806%2970656-9

7 January 2021

Other bacteria and HIV disease

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2806%2970656-9

7 January 2021

Infections associated with Bartonella species in persons infected with human immunodeficiency virus

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2806%2970656-9

7 January 2021

B lymphocyte dysfunctions in HIV infection

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2806%2970656-9

7 January 2021

Invasive pneumococcal disease in a cohort of HIV-infected adults: incidence and risk factors, 1990-2003.

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2806%2970656-9

7 January 2021

Invasive pneumococcal disease in patients infected with HIV: still a threat in the era of highly active antiretroviral therapy.

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2806%2970656-9

7 January 2021

Declining incidence of invasive Streptococcus pneumoniae infections among persons with AIDS in an era of highly active antiretroviral therapy, 1995-2000.

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2806%2970656-9

7 January 2021

Pulmonary Infiltrates in HIV-Infected Patients in the Highly Active Antiretroviral Therapy Era in Spain

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2806%2970656-9

7 January 2021

Changes in bloodstream infections in HIV-positive patients in a university hospital in Spain (1995-1997).

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2806%2970656-9

7 January 2021

Bacterial Disease in HIV-Infected Patients

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2806%2970656-9

7 January 2021

Induction of granulocyte colony-stimulating factor by acute febrile infection but not by neutropenia in HIV-seropositive individuals

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2806%2970656-9

7 January 2021

Neutropenia, neutrophil dysfunction, and bacterial infection in patients with human immunodeficiency virus disease: the role of granulocyte colony-stimulating factor

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2806%2970656-9

7 January 2021

Granulocyte-macrophage colony-stimulating factor augments phagocytosis of Mycobacterium avium complex by human immunodeficiency virus type 1-infected monocytes/macrophages in vitro and in vivo.

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2806%2970656-9

7 January 2021

A Phase III Study of Recombinant Human Interferon Gamma to Prevent Opportunistic Infections in Advanced HIV Disease

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2806%2970656-9

7 January 2021

Immunotherapeutic uses of CpG oligodeoxynucleotides

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2806%2970656-9

7 January 2021

Effective postexposure treatment of retrovirus-induced disease with immunostimulatory DNA containing CpG motifs

1 reference

https://api.crossref.org/works/10.1016%2FS1473-3099%2806%2970656-9

7 January 2021

10.1016/S1473-3099(06)70656-9

Identifiers

DOI

1 reference

15 August 2017

1 reference

PubMed ID

17123899