Hepatocyte-specific c-Met deletion disrupts redox homeostasis and sensitizes to Fas-mediated apoptosis. (Q36662751)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18348981%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

title

Hepatocyte-specific c-Met deletion disrupts redox homeostasis and sensitizes to Fas-mediated apoptosis (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18348981%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18348981%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

author name string

Valentina M Factor

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18348981%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

Pal Kaposi-Novak

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18348981%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

Cedric Coulouarn

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18348981%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

Elizabeth A Conner

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18348981%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

Snorri S Thorgeirsson

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18348981%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

language of work or name

English

0 references

publication date

18 March 2008

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18348981%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

number of pages

9

1 reference

Journal of Biological Chemistry

inferred from page(s)

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18348981%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

volume

283

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18348981%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

issue

21

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18348981%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

page(s)

14581-14589

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18348981%20AND%20SRC:MED&resulttype=core&format=json

Genetic targeting of the kinase activity of the Met receptor in cancer cells

4 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2386934

Hepatocyte growth factor protects rat RINm5F cell line against free fatty acid-induced apoptosis by counteracting oxidative stress.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2386934

Suppression of reactive oxygen species and neurodegeneration by the PGC-1 transcriptional coactivators

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2386934

NF-kappaB activation by reactive oxygen species: fifteen years later

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2386934

Met-regulated expression signature defines a subset of human hepatocellular carcinomas with poor prognosis and aggressive phenotype

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2386934

Nox1-dependent reactive oxygen generation is regulated by Rac1

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2386934

Bile salt-induced apoptosis involves NADPH oxidase isoform activation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2386934

Vitamin E deficiency induces liver nuclear factor-kappaB DNA-binding activity and changes in related genes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2386934

Involvement of NADPH oxidase isoforms and Src family kinases in CD95-dependent hepatocyte apoptosis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2386934

Hepatic mitochondrial glutathione: transport and role in disease and toxicity.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2386934

Role of NF-kappaB signaling in hepatocyte growth factor/scatter factor-mediated cell protection

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2386934

HGF/SF-Met signaling in tumor progression

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2386934

Hepatocyte growth factor suppresses vascular endothelial growth factor-induced expression of endothelial ICAM-1 and VCAM-1 by inhibiting the nuclear factor-kappaB pathway.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2386934

In vitro differentiation of rat liver derived stem cells results in sensitization to TNFalpha-mediated apoptosis.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2386934

Sensitization of T cells to apoptosis--a role for ROS?

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2386934

Hepatocyte growth factor/c-met signaling pathway is required for efficient liver regeneration and repair

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2386934

Stat3 protects against Fas-induced liver injury by redox-dependent and -independent mechanisms

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2386934

Fas-stimulated generation of reactive oxygen species or exogenous oxidative stress sensitize cells to Fas-mediated apoptosis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2386934

The CD95(APO-1/Fas) DISC and beyond

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2386934

Activation of NF-kappaB is essential for hepatocyte growth factor-mediated proliferation and tubulogenesis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2386934

Hepatocyte growth factor, but not insulin-like growth factor I, protects podocytes against cyclosporin A-induced apoptosis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2386934

Attenuation of endogenous oxidative stress-induced cell death by cytochrome P450 inhibitors in primary cultures of rat hepatocytes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2386934

Elevation of glutathione level in rat hepatocytes by hepatocyte growth factor via induction of gamma-glutamylcysteine synthetase

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2386934

Regulation of gene expression by reactive oxygen

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2386934

Emerging multipotent aspects of hepatocyte growth factor

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2386934

Stable expression of human CYP2E1 in Chinese hamster cells: high sensitivity to N,N-dimethylnitrosamine in cytotoxicity testing

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2386934

Placental defect and embryonic lethality in mice lacking hepatocyte growth factor/scatter factor

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2386934

Scatter factor/hepatocyte growth factor is essential for liver development

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2386934

Lethal effect of the anti-Fas antibody in mice

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2386934

Inhibition of hypoxia/reoxygenation-induced oxidative stress in HGF-stimulated antiapoptotic signaling: role of PI3-K and Akt kinase upon rac1.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2386934

Ceramide-induced apoptosis: role of catalase and hepatocyte growth factor

28 June 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707733200

Hepatocyte growth factor induces Mcl-1 in primary human hepatocytes and inhibits CD95-mediated apoptosis via Akt.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707733200

Met signals hepatocyte survival by preventing Fas-triggered FLIP degradation in a PI3k-Akt-dependent manner.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707733200

Loss of hepatocyte growth factor/c-Met signaling pathway accelerates early stages of N-nitrosodiethylamine induced hepatocarcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707733200

EGF blocks NADPH oxidase activation by TGF-beta in fetal rat hepatocytes, impairing oxidative stress, and cell death.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707733200

A mechanism of cell survival: sequestration of Fas by the HGF receptor Met.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707733200

Protein-tyrosine phosphatase 1B deficiency protects against Fas-induced hepatic failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707733200

Glutathione therapy: from prodrugs to genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707733200

Source of early reactive oxygen species in the apoptosis induced by transforming growth factor-beta in fetal rat hepatocytes

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2386934

Akt protects mouse hepatocytes from TNF-alpha- and Fas-mediated apoptosis through NK-kappa B activation

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2386934

Pathway specificity for Met signalling

20 September 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707733200

High-performance liquid chromatography of thiols and disulfides: dinitrophenol derivatives

21 January 2018

1 reference

12 December 2020

Reduced growth capacity of hepatocytes from c-myc and c-myc/TGF-alpha transgenic mice in primary culture

1 reference

12 December 2020

Anti-apoptotic signaling by hepatocyte growth factor/Met via the phosphatidylinositol 3-kinase/Akt and mitogen-activated protein kinase pathways

1 reference

12 December 2020

Bid-dependent generation of oxygen radicals promotes death receptor activation-induced apoptosis in murine hepatocytes

1 reference

12 December 2020

Microsomal lipid peroxidation

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M707733200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18348981%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18348981%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

PubMed publication ID

18348981

1 reference