Hepatocyte growth factor induces Mcl-1 in primary human hepatocytes and inhibits CD95-mediated apoptosis via Akt. (Q48003529)

7 February 2018

title

Hepatocyte growth factor induces Mcl-1 in primary human hepatocytes and inhibits CD95-mediated apoptosis via Akt. (English)

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7 February 2018

author name string

Henning Schulze-Bergkamen

1

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7 February 2018

Dirk Brenner

2

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7 February 2018

Andreas Krueger

3

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7 February 2018

Dorothee Suess

4

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7 February 2018

Stefanie C Fas

5

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7 February 2018

Christian R Frey

6

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7 February 2018

Andreas Dax

7

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7 February 2018

Dorothea Zink

8

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7 February 2018

Peter Büchler

9

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7 February 2018

Martina Müller

10

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7 February 2018

Peter H Krammer

11

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7 February 2018

language of work or name

English

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publication date

1 March 2004

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7 February 2018

published in

Hepatology

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7 February 2018

volume

39

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7 February 2018

issue

3

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7 February 2018

page(s)

645-654

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7 February 2018

The TNF and TNF receptor superfamilies: integrating mammalian biology

cites work

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Involvement of the CD95 (APO-1/Fas) receptor and ligand in liver damage.

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Primary human hepatocytes--a valuable tool for investigation of apoptosis and hepatitis B virus infection

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Two CD95 (APO-1/Fas) signaling pathways

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Relief of extrinsic pathway inhibition by the Bid-dependent mitochondrial release of Smac in Fas-mediated hepatocyte apoptosis

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Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosis

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The many faces of hepatocyte growth factor: from hepatopoiesis to hematopoiesis

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Molecular cloning and expression of human hepatocyte growth factor

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Attenuated acute liver injury in mice by naked hepatocyte growth factor gene transfer into skeletal muscle with electroporation

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A mechanism of cell survival: sequestration of Fas by the HGF receptor Met.

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Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

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Role of glycogen synthase kinase-3 in the phosphatidylinositol 3-Kinase/Akt cell survival pathway

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HGF-mediated apoptosis via p53/bax-independent pathway activating JNK1.

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Akt signaling mediates postnatal heart growth in response to insulin and nutritional status

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A new approach for measurement of cytotoxicity using colorimetric assay

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A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry

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FLICE is predominantly expressed as two functionally active isoforms, caspase-8/a and caspase-8/b.

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Differential modulation of apoptosis sensitivity in CD95 type I and type II cells.

21 January 2018

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Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

21 January 2018

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Bcl-2 and Bcl-xL inhibit CD95-mediated apoptosis by preventing mitochondrial release of Smac/DIABLO and subsequent inactivation of X-linked inhibitor-of-apoptosis protein

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MCL1 provides a window on the role of the BCL2 family in cell proliferation, differentiation and tumorigenesis

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Serine phosphorylation of STAT3 is essential for Mcl-1 expression and macrophage survival

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FLICE-inhibitory proteins: regulators of death receptor-mediated apoptosis

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Mechanisms of liver cell injury

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Prediction of outcome in fulminant hepatic failure by serum human hepatocyte growth factor

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Keratinocyte growth factor protects murine hepatocytes from tumor necrosis factor-induced apoptosis in vivo and in vitro

21 January 2018

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Phosphoinositide 3-kinase, but not mitogen-activated protein kinase, pathway is involved in hepatocyte growth factor-mediated protection against bile acid-induced apoptosis in cultured rat hepatocytes

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Transgenic expression in the liver of truncated Met blocks apoptosis and permits immortalization of hepatocytes

21 January 2018

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Phosphatidylinositol 3-kinase/Akt activity regulates c-FLIP expression in tumor cells

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Resistance of rat hepatocytes against bile acid-induced apoptosis in cholestatic liver injury is due to nuclear factor-kappa B activation

21 January 2018

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The involvement of PI 3-K/Akt-dependent up-regulation of Mcl-1 in the prevention of apoptosis of Hep3B cells by interleukin-6.

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STAT3 is a serine kinase target in T lymphocytes. Interleukin 2 and T cell antigen receptor signals converge upon serine 727.

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PKB binding proteins. Getting in on the Akt.

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7 January 2021

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7 January 2021

CD95-induced apoptosis in human liver disease

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7 January 2021

RNA interference targeting Fas protects mice from fulminant hepatitis

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7 January 2021

Interactions between scatter factors and their receptors: hints for therapeutic applications

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7 January 2021

Abrogation of Fas-induced fulminant hepatic failure in mice by hepatocyte growth factor

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7 January 2021

The role of protein kinase B and mitogen-activated protein kinase in epidermal growth factor and tumor necrosis factor alpha-mediated rat hepatocyte survival and apoptosis

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7 January 2021

Monoclonal antibody-mediated tumor regression by induction of apoptosis.

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7 January 2021

The antiapoptotic gene mcl-1 is up-regulated by the phosphatidylinositol 3-kinase/Akt signaling pathway through a transcription factor complex containing CREB

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7 January 2021

Hepatocyte growth factor prevents endotoxin-induced lethal hepatic failure in mice

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7 January 2021

Deoxycholic acid (DCA) causes ligand-independent activation of epidermal growth factor receptor (EGFR) and FAS receptor in primary hepatocytes: inhibition of EGFR/mitogen-activated protein kinase-signaling module enhances DCA-induced apoptosis.

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7 January 2021

Identifiers

DOI

10.1002/HEP.20138

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7 February 2018

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7 February 2018