Topoisomerase 1-mediated removal of ribonucleotides from nascent leading-strand DNA (Q36677913)

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23 February 2020

title

Topoisomerase 1-mediated removal of ribonucleotides from nascent leading-strand DNA (English)

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23 February 2020

4

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23 February 2020

Andrei Chabes

5

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23 February 2020

Thomas A Kunkel

6

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23 February 2020

author name string

Jessica S Williams

1

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23 February 2020

Dana J Smith

2

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23 February 2020

Lisette Marjavaara

3

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23 February 2020

publication date

31 January 2013

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23 February 2020

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23 February 2020

volume

49

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23 February 2020

issue

5

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23 February 2020

page(s)

1010-1015

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describes a project that uses

23 February 2020

ImageQuant

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11 June 2022

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cites work

Exonuclease 1 preferentially repairs mismatches generated by DNA polymerase α

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Mismatch repair balances leading and lagging strand DNA replication fidelity.

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RNase H2-initiated ribonucleotide excision repair.

30 September 2017

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Enzymatic removal of ribonucleotides from DNA is essential for mammalian genome integrity and development.

30 September 2017

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RNase H and postreplication repair protect cells from ribonucleotides incorporated in DNA

30 September 2017

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Endogenous DNA replication stress results in expansion of dNTP pools and a mutator phenotype

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The major roles of DNA polymerases epsilon and delta at the eukaryotic replication fork are evolutionarily conserved

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Mutagenic processing of ribonucleotides in DNA by yeast topoisomerase I

30 September 2017

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Mismatch repair-independent tandem repeat sequence instability resulting from ribonucleotide incorporation by DNA polymerase ε.

30 September 2017

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Topoisomerase 1 provokes the formation of short deletions in repeated sequences upon high transcription in Saccharomyces cerevisiae

30 September 2017

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Role for topoisomerase 1 in transcription-associated mutagenesis in yeast

30 September 2017

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Substrate channeling in mammalian base excision repair pathways: passing the baton

30 September 2017

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Genome instability due to ribonucleotide incorporation into DNA.

30 September 2017

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Abundant ribonucleotide incorporation into DNA by yeast replicative polymerases

30 September 2017

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Interplay of DNA repair pathways controls methylation damage toxicity in Saccharomyces cerevisiae

30 September 2017

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Division of labor at the eukaryotic replication fork

30 September 2017

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Mre11-Rad50-Nbs1 is a keystone complex connecting DNA repair machinery, double-strand break signaling, and the chromatin template.

30 September 2017

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Yeast DNA polymerase epsilon participates in leading-strand DNA replication

30 September 2017

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Mutations in genes encoding ribonuclease H2 subunits cause Aicardi-Goutières syndrome and mimic congenital viral brain infection

30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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Saccharomyces cerevisiae RNase H(35) functions in RNA primer removal during lagging-strand DNA synthesis, most efficiently in cooperation with Rad27 nuclease

30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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PubMed

https://pubmed.ncbi.nlm.nih.gov/23375499

12 December 2020

inferred from PubMed ID database lookup

Ribonuclease H from K562 human erythroleukemia cells. Purification, characterization, and substrate specificity

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23375499

12 December 2020

inferred from PubMed ID database lookup

Substrate specificity of human RNase H1 and its role in excision repair of ribose residues misincorporated in DNA

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23375499

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1016/J.MOLCEL.2012.12.021

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23 February 2020

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23 February 2020

PubMed publication ID

23375499

1 reference

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