Rho-associated kinase (ROCK) function is essential for cell cycle progression, senescence and tumorigenesis (Q36703612)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26765561%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

title

Rho-associated kinase (ROCK) function is essential for cell cycle progression, senescence and tumorigenesis (English)

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5 March 2020

1

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5 March 2020

Faraz Khosravi Mardakheh

2

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5 March 2020

Jonathan D Worboys

7

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5 March 2020

author name string

Afshan McCarthy

3

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5 March 2020

Maggie Yeo

4

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5 March 2020

Gordon W Stamp

5

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5 March 2020

Angela Paul

6

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5 March 2020

Amine Sadok

8

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5 March 2020

Claus Jørgensen

9

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5 March 2020

Sabrina Guichard

10

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5 March 2020

Christopher J Marshall

11

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5 March 2020

language of work or name

English

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publication date

14 January 2016

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5 March 2020

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5 March 2020

volume

5

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5 March 2020

page(s)

e12994

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describes a project that uses

5 March 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4798951/fullTextXML

inferred from PubMed Central ID database lookup

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RhoA regulates G1-S progression of gastric cancer cells by modulation of multiple INK4 family tumor suppressors

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Oncogenic Braf induces melanocyte senescence and melanoma in mice

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Braf(V600E) cooperates with Pten loss to induce metastatic melanoma

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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Membrane blebbing during apoptosis results from caspase-mediated activation of ROCK I.

30 September 2017

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30 September 2017

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Rho-kinase/ROCK is involved in cytokinesis through the phosphorylation of myosin light chain and not ezrin/radixin/moesin proteins at the cleavage furrow.

30 September 2017

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Rho-kinase inhibitor retards migration and in vivo dissemination of human prostate cancer cells

30 September 2017

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Inhibitory phosphorylation site for Rho-associated kinase on smooth muscle myosin phosphatase

30 September 2017

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Phosphorylation of myosin-binding subunit (MBS) of myosin phosphatase by Rho-kinase in vivo

30 September 2017

1 reference

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p45SKP2 promotes p27Kip1 degradation and induces S phase in quiescent cells

30 September 2017

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Cofilin phosphorylation by LIM-kinase 1 and its role in Rac-mediated actin reorganization

30 September 2017

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Formation of actin stress fibers and focal adhesions enhanced by Rho-kinase

30 September 2017

1 reference

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Phosphorylation and activation of myosin by Rho-associated kinase (Rho-kinase)

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4798951

Regulation of myosin phosphatase by Rho and Rho-associated kinase (Rho-kinase)

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4798951

The Cdk-associated protein Cks1 functions both in G1 and G2 in Saccharomyces cerevisiae

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4798951

Association of p53 binding and immortalization of primary C57BL/6 mouse embryo fibroblasts by using simian virus 40 T-antigen mutants bearing internal overlapping deletion mutations

30 September 2017

1 reference

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Spontaneous and carcinogen-induced tumorigenesis in p53-deficient mice.

30 September 2017

1 reference

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SV40 large tumor antigen forms a specific complex with the product of the retinoblastoma susceptibility gene

30 September 2017

1 reference

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Use and properties of ROCK-specific inhibitor Y-27632.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4798951

Transformation mediated by RhoA requires activity of ROCK kinases

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4798951

An essential part for Rho-associated kinase in the transcellular invasion of tumor cells.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4798951

Bypass of senescence after disruption of p21CIP1/WAF1 gene in normal diploid human fibroblasts

28 June 2018

1 reference

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Ca2+, cAMP, and changes in myosin phosphorylation during contraction of smooth muscle

28 June 2018

1 reference

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Protocols to detect senescence-associated beta-galactosidase (SA-betagal) activity, a biomarker of senescent cells in culture and in vivo

28 June 2018

1 reference

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Combination of FASP and StageTip-based fractionation allows in-depth analysis of the hippocampal membrane proteome

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4798951

Requirement for Rac1 in a K-ras induced lung cancer in the mouse.

5 September 2018

1 reference

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Context-specific requirements for Fgfr1 signaling through Frs2 and Frs3 during mouse development.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4798951

ROCK-I and ROCK-II cooperatively regulate closure of eyelid and ventral body wall in mouse embryo

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4798951

Endogenous oncogenic K-ras(G12D) stimulates proliferation and widespread neoplastic and developmental defects.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4798951

A CDK-independent function of mammalian Cks1: targeting of SCF(Skp2) to the CDK inhibitor p27Kip1.

5 September 2018

1 reference

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Role of citron kinase as a target of the small GTPase Rho in cytokinesis

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4798951

Increased p16 expression with first senescence arrest in human mammary epithelial cells and extended growth capacity with p16 inactivation

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4798951

Erratum: Stress fibres take shape

5 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.7554%2FELIFE.12203

Rho-associated kinase directly induces smooth muscle contraction through myosin light chain phosphorylation

21 January 2018

1 reference

12 December 2020

Specific accumulation of Rho-associated kinase at the cleavage furrow during cytokinesis: cleavage furrow-specific phosphorylation of intermediate filaments

1 reference

12 December 2020

The differential effects of mutant p53 alleles on advanced murine lung cancer

1 reference

12 December 2020

Human mammary epithelial cell transformation through the activation of phosphatidylinositol 3-kinase

1 reference

12 December 2020

Identifiers

DOI

10.7554/ELIFE.12203

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26765561%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26765561%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

PubMed publication ID

26765561

1 reference