c-Met and hepatocyte growth factor: potential as novel targets in cancer therapy (Q36731520)

15 August 2017

1 reference

title

c-Met and hepatocyte growth factor: potential as novel targets in cancer therapy (English)

1 reference

15 August 2017

2

Ravi Salgia

1 reference

15 August 2017

Martin Sattler

1

1 reference

15 August 2017

1 March 2007

1 reference

15 August 2017

Current Oncology Reports

1 reference

15 August 2017

9

1 reference

15 August 2017

2

1 reference

15 August 2017

102-108

1 reference

https://scigraph.springernature.com/pub.10.1007/s11912-007-0005-4

15 August 2017

0 references

cites work

Dimerization mediated through a leucine zipper activates the oncogenic potential of the met receptor tyrosine kinase

1 reference

https://api.crossref.org/works/10.1007%2FS11912-007-0005-4

A Prospective Study of Congenital Cytomegalovirus Infection in Japan

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11912-007-0005-4

Expression of c-met/HGF receptor in human non-small cell lung carcinomas in vitro and in vivo and its prognostic significance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11912-007-0005-4

Overexpression and activation of hepatocyte growth factor/scatter factor in human non-small-cell lung carcinomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11912-007-0005-4

c-MET expression in myofibroblasts: role in autocrine activation and prognostic significance in lung adenocarcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11912-007-0005-4

Activation of hepatocyte growth factor-met autocrine loop enhances tumorigenicity in a human lung adenocarcinoma cell line.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11912-007-0005-4

A novel small molecule met inhibitor induces apoptosis in cells transformed by the oncogenic TPR-MET tyrosine kinase

21 January 2018

1 reference

12 December 2020

Met proto-oncogene juxtamembrane rare variations in mouse and humans: differential effects of Arg and Cys alleles on mouse lung tumorigenesis.

1 reference

12 December 2020

Placental defect and embryonic lethality in mice lacking hepatocyte growth factor/scatter factor

1 reference

12 December 2020

Inhibition of c-Met and prevention of spontaneous metastatic spreading by the 2-indolinone RPI-1.

1 reference

12 December 2020

Role of chemotherapy and the receptor tyrosine kinases KIT, PDGFRalpha, PDGFRbeta, and Met in large-cell neuroendocrine carcinoma of the lung

1 reference

12 December 2020

Germline and somatic mutations in the tyrosine kinase domain of the MET proto-oncogene in papillary renal carcinomas

1 reference

12 December 2020

Autophosphorylation modulates the kinase activity and oncogenic potential of the Met receptor tyrosine kinase

1 reference

12 December 2020

Molecular cloning of a new transforming gene from a chemically transformed human cell line.

1 reference

12 December 2020

Cbl-CIN85-endophilin complex mediates ligand-induced downregulation of EGF receptors

1 reference

12 December 2020

Hepatocyte growth factor, a versatile signal for developing neurons

1 reference

12 December 2020

Phosphorylation of serine 985 negatively regulates the hepatocyte growth factor receptor kinase

1 reference

12 December 2020

An 11-amino acid sequence from c-met initiates epithelial chemotaxis via phosphatidylinositol 3-kinase and phospholipase C.

1 reference

12 December 2020

Transgenic mice overexpressing hepatocyte growth factor in the airways show increased susceptibility to lung cancer

1 reference

12 December 2020

The HGF receptor family: unconventional signal transducers for invasive cell growth

1 reference

12 December 2020

Modulation of the c-Met/hepatocyte growth factor pathway in small cell lung cancer.

1 reference

12 December 2020

Scatter factor/hepatocyte growth factor is essential for liver development

1 reference

12 December 2020

The clinical significance of hepatocyte growth factor for non-small cell lung cancer

1 reference

12 December 2020

The mutationally activated Met receptor mediates motility and metastasis

1 reference

12 December 2020

The semaphorin 4D receptor controls invasive growth by coupling with Met

1 reference

12 December 2020

A novel one-armed anti-c-Met antibody inhibits glioblastoma growth in vivo

1 reference

12 December 2020

Novel mutations of the MET proto-oncogene in papillary renal carcinomas.

1 reference

12 December 2020

The geldanamycins are potent inhibitors of the hepatocyte growth factor/scatter factor-met-urokinase plasminogen activator-plasmin proteolytic network

1 reference

12 December 2020

Association of immunoreactive hepatocyte growth factor with poor survival in resectable non-small cell lung cancer

1 reference

12 December 2020

A novel germ line juxtamembrane Met mutation in human gastric cancer

1 reference

12 December 2020

A family of transmembrane proteins with homology to the MET-hepatocyte growth factor receptor

1 reference

12 December 2020

HGF: a multifunctional growth factor controlling cell scattering.

1 reference

12 December 2020

Novel targeted therapies to overcome imatinib mesylate resistance in chronic myeloid leukemia (CML).

1 reference

12 December 2020

Met and hepatocyte growth factor/scatter factor expression in human gliomas

1 reference

12 December 2020

A Peptide Representing the Carboxyl-terminal Tail of the Met Receptor Inhibits Kinase Activity and Invasive Growth

1 reference

12 December 2020

Essential role for the c-met receptor in the migration of myogenic precursor cells into the limb bud

1 reference

12 December 2020

Constitutive c-Met signaling through a nonautocrine mechanism promotes metastasis in a transgenic transplantation model

1 reference

12 December 2020

Structural and functional domains critical for constitutive activation of the HGF-receptor (Met).

1 reference

12 December 2020

Downregulation of E-cadherin and Desmoglein 1 by autocrine hepatocyte growth factor during melanoma development

1 reference

12 December 2020

Purification and subunit structure of hepatocyte growth factor from rat platelets

1 reference

12 December 2020

Human hepatocyte growth factor in plasma from patients with fulminant hepatic failure.

1 reference

12 December 2020

Internal tandem duplication of the FLT3 gene is preferentially seen in acute myeloid leukemia and myelodysplastic syndrome among various hematological malignancies. A study on a large series of patients and cell lines

1 reference

12 December 2020

STAM and Hrs are subunits of a multivalent ubiquitin-binding complex on early endosomes

1 reference

12 December 2020

Met receptor tyrosine kinase: enhanced signaling through adapter proteins

1 reference

12 December 2020

Branching tubulogenesis but not scatter of madin-darby canine kidney cells requires a functional Grb2 binding site in the Met receptor tyrosine kinase

1 reference

12 December 2020

Down-regulation of MET, the receptor for hepatocyte growth factor.

1 reference

12 December 2020

Activation of the Met receptor by cell attachment induces and sustains hepatocellular carcinomas in transgenic mice

1 reference

12 December 2020

MET overexpression turns human primary osteoblasts into osteosarcomas.

1 reference

12 December 2020

Coexpression of hepatocyte growth factor and receptor (Met) in human breast carcinoma

1 reference

12 December 2020

A high-affinity conformation of Hsp90 confers tumour selectivity on Hsp90 inhibitors

1 reference

12 December 2020

Mutation of the c-Cbl TKB domain binding site on the Met receptor tyrosine kinase converts it into a transforming protein

1 reference

12 December 2020

Down-regulation of c-Met inhibits growth in the liver of human colorectal carcinoma cells

1 reference

12 December 2020

Inhibition of growth, invasion, and metastasis of human pancreatic carcinoma cells by NK4 in an orthotopic mouse model

1 reference

12 December 2020

Mutant Met-mediated transformation is ligand-dependent and can be inhibited by HGF antagonists

1 reference

12 December 2020

The endophilin-CIN85-Cbl complex mediates ligand-dependent downregulation of c-Met

1 reference

12 December 2020

Nk4, a new HGF/SF variant, is an antagonist to the influence of HGF/SF on the motility and invasion of colon cancer cells

1 reference

12 December 2020

Mutation of juxtamembrane tyrosine residue 1001 suppresses loss-of-function mutations of the met receptor in epithelial cells.

1 reference

12 December 2020

c-MET mutational analysis in small cell lung cancer: novel juxtamembrane domain mutations regulating cytoskeletal functions

1 reference

12 December 2020

Gab1 coupling to the HGF/Met receptor multifunctional docking site requires binding of Grb2 and correlates with the transforming potential.

1 reference

12 December 2020

A selective small molecule inhibitor of c-Met kinase inhibits c-Met-dependent phenotypes in vitro and exhibits cytoreductive antitumor activity in vivo

1 reference

12 December 2020

Crystal structure of the HGF beta-chain in complex with the Sema domain of the Met receptor

1 reference

12 December 2020

The odd couple: signal transduction and endocytosis

1 reference

12 December 2020

Met/Hepatocyte growth factor receptor ubiquitination suppresses transformation and is required for Hrs phosphorylation

1 reference

12 December 2020

RNA interference reveals that ligand-independent met activity is required for tumor cell signaling and survival

1 reference

12 December 2020

Structural basis of hepatocyte growth factor/scatter factor and MET signalling

1 reference

12 December 2020

A role for common fragile site induction in amplification of human oncogenes

1 reference

12 December 2020

The Sema domain of Met is necessary for receptor dimerization and activation

1 reference

12 December 2020

Amplification of MET may identify a subset of cancers with extreme sensitivity to the selective tyrosine kinase inhibitor PHA-665752

1 reference

12 December 2020

K252a inhibits the oncogenic properties of Met, the HGF receptor

1 reference

12 December 2020

The Met/HGF receptor is over-expressed in human osteosarcomas and is activated by either a paracrine or an autocrine circuit

1 reference

12 December 2020

A multifunctional docking site mediates signaling and transformation by the hepatocyte growth factor/scatter factor receptor family

1 reference

12 December 2020

Gains, losses, and amplifications of genomic materials in primary gastric cancers analyzed by comparative genomic hybridization

1 reference

12 December 2020

Scatter factor is a fibroblast-derived modulator of epithelial cell mobility

1 reference

12 December 2020

10.1007/S11912-007-0005-4

Identifiers

DOI

1 reference

15 August 2017

1 reference

PubMed ID

17288874