Regulation of skeletal growth and mineral acquisition by the GH/IGF-1 axis: Lessons from mouse models. (Q36734567)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26432542%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

title

Regulation of skeletal growth and mineral acquisition by the GH/IGF-1 axis: Lessons from mouse models (English)

1 reference

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25 February 2020

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26432542%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

author name string

Olle Isaksson

series ordinal

2

1 reference

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25 February 2020

publication date

28 September 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26432542%20AND%20SRC:MED&resulttype=core&format=json

Growth Hormone & I G F Research

25 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26432542%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

volume

28

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26432542%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

page(s)

26-42

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GH/STAT5 signaling during the growth period in livers of mice overexpressing GH.

25 February 2020

cites work

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Liver-specific deletion of the growth hormone receptor reveals essential role of growth hormone signaling in hepatic lipid metabolism

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Serum IGF-1 determines skeletal strength by regulating subperiosteal expansion and trait interactions

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Does adiposity status influence femoral cortical strength in rodent models of growth hormone deficiency?

30 September 2017

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Serum complexes of insulin-like growth factor-1 modulate skeletal integrity and carbohydrate metabolism

30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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Mechanical stimulation of bone in vivo reduces osteocyte expression of Sost/sclerostin

30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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Impaired skeletal growth in mice with haploinsufficiency of IGF-I: genetic evidence that differences in IGF-I expression could contribute to peak bone mineral density differences

30 September 2017

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Extracellular nucleotides activate Runx2 in the osteoblast-like HOBIT cell line: a possible molecular link between mechanical stress and osteoblasts' response

30 September 2017

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30 September 2017

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SOCS2 negatively regulates growth hormone action in vitro and in vivo

30 September 2017

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Insulin-like growth factor-binding protein-5 induces a gender-related decrease in bone mineral density in transgenic mice

30 September 2017

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30 September 2017

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30 September 2017

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Paracrine Overexpression of IGFBP‐4 in Osteoblasts of Transgenic Mice Decreases Bone Turnover and Causes Global Growth Retardation

30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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Bone homeostasis in growth hormone receptor-null mice is restored by IGF-I but independent of Stat5.

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Disproportional skeletal growth and markedly decreased bone mineral content in growth hormone receptor -/- mice.

30 September 2017

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30 September 2017

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Mechanical strain stimulates ROS cell proliferation through IGF-II and estrogen through IGF-I.

30 September 2017

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Normal growth and development in the absence of hepatic insulin-like growth factor I

30 September 2017

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Liver-derived insulin-like growth factor I (IGF-I) is the principal source of IGF-I in blood but is not required for postnatal body growth in mice

30 September 2017

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A non-destructive technique for 3-D microstructural phenotypic characterisation of bones in genetically altered mice: preliminary data in growth hormone transgenic animals and normal controls

30 September 2017

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The conserved SOCS box motif in suppressors of cytokine signaling binds to elongins B and C and may couple bound proteins to proteasomal degradation

30 September 2017

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Anti-latent TGF-beta binding protein-1 antibody or synthetic oligopeptides inhibit extracellular matrix expression induced by stretch in cultured rat mesangial cells

30 September 2017

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Jak2 deficiency defines an essential developmental checkpoint in definitive hematopoiesis

30 September 2017

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Jak2 is essential for signaling through a variety of cytokine receptors

30 September 2017

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Requirement of STAT5b for sexual dimorphism of body growth rates and liver gene expression

30 September 2017

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Elevated blood pressure and enhanced myocardial contractility in mice with severe IGF-1 deficiency

30 September 2017

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Genetic ablation of IGFBP-2 suggests functional redundancy in the IGFBP family

30 September 2017

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Mice carrying null mutations of the genes encoding insulin-like growth factor I (Igf-1) and type 1 IGF receptor (Igf1r)

30 September 2017

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GHRH receptor of little mice contains a missense mutation in the extracellular domain that disrupts receptor function

30 September 2017

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Expression of insulin-like growth factor-I in transgenic mice

30 September 2017

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Mouse models of IGF-I deficiency generated by gene targeting

30 September 2017

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A dual effector theory of growth-hormone action

30 September 2017

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Accelerated growth and visceral lesions in transgenic mice expressing foreign genes of the growth hormone family: an overview

30 September 2017

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Osteoblast-specific expression of growth hormone stimulates bone growth in transgenic mice

30 September 2017

1 reference

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The GH-transgenic mouse as an experimental model for growth research: clinical and pathological studies.

30 September 2017

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Growth hormone induces multiplication of the slowly cycling germinal cells of the rat tibial growth plate

30 September 2017

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IGF and IGF-binding protein expression in the growth plate of normal, dexamethasone-treated and human IGF-II transgenic mice

30 September 2017

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Mechanical strain stimulates osteoblast proliferation through the estrogen receptor in males as well as females

28 June 2018

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IGF-I deficient mice show reduced peripheral nerve conduction velocities and decreased axonal diameters and respond to exogenous IGF-I treatment

28 June 2018

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The estrogen receptor's involvement in osteoblasts' adaptive response to mechanical strain

28 June 2018

1 reference

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Dexamethasone impairs growth hormone (GH)-stimulated growth by suppression of local insulin-like growth factor (IGF)-I production and expression of GH- and IGF-I-receptor in cultured rat chondrocytes

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4809789

IGF-I is required for normal embryonic growth in mice

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4809789

Inactivation of the IGF-I gene in mice results in perinatal lethality

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4809789

Mechanical loading stimulates rapid changes in periosteal gene expression.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4809789

Skeletal unloading induces resistance to insulin-like growth factor I.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4809789

Expression of human growth hormone-releasing factor in transgenic mice results in increased somatic growth.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4809789

Regulation by growth hormone of number of chondrocytes containing IGF-I in rat growth plate

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4809789

Transgenic mice with inducible dwarfism.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4809789

Expression of insulin-like growth factor I stimulates normal somatic growth in growth hormone-deficient transgenic mice.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4809789

Parental imprinting of the mouse insulin-like growth factor II gene.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4809789

Growth characteristics of metallothionein-human growth hormone transgenic mice as compared to mice selected for high eight-week body weight and unselected controls. II. Skeleton.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4809789

Growth characteristics of metallothionein-human growth hormone transgenic mice as compared to mice selected for high eight-week body weight and unselected controls. I. Body weight gain and external body dimensions.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4809789

Mechano-transduction in osteoblastic cells involves strain-regulated estrogen receptor alpha-mediated control of insulin-like growth factor (IGF) I receptor sensitivity to Ambient IGF, leading to phosphatidylinositol 3-kinase/AKT-dependent Wnt/LRP5

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4809789

An experimental model of partial insulin-like growth factor-1 deficiency in mice.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4809789

Osteocyte-derived insulin-like growth factor I is essential for determining bone mechanosensitivity.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4809789

Disruption of the insulin-like growth factor-1 gene in osteocytes impairs developmental bone growth in mice.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4809789

Growth hormone receptor: structure function relationships.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4809789

Insulin-like growth factor-I treatment in primary growth hormone insensitivity: effect of recombinant human IGF-I (rhIGF-I) and rhIGF-I/rhIGF-binding protein-3 complex

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4809789

Increased bone mass, altered trabecular architecture and modified growth plate organization in the growing skeleton of SOCS2 deficient mice.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4809789

Impact of pregnancy-associated plasma protein-a deletion on the adult murine skeleton

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4809789

IGF-I receptor is required for the anabolic actions of parathyroid hormone on bone

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4809789

Pregnancy associated plasma protein-A is necessary for expeditious fracture healing in mice.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4809789

Effect of mechanical loading on insulin-like growth factor-I gene expression in rat tibia.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4809789

Postnatally elevated levels of insulin-like growth factor (IGF)-II fail to rescue the dwarfism of IGF-I-deficient mice except kidney weight.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4809789

Insulin-like growth factor-I is essential for embryonic bone development

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4809789

Insulin-like growth factor binding protein (IGFBP-1) involvement in intrauterine growth retardation: study on IGFBP-1 overexpressing transgenic mice

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4809789

Up-regulation of the Wnt, estrogen receptor, insulin-like growth factor-I, and bone morphogenetic protein pathways in C57BL/6J osteoblasts as opposed to C3H/HeJ osteoblasts in part contributes to the differential anabolic response to fluid shear

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4809789

Postnatal growth and bone mass in mice with IGF-I haploinsufficiency.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4809789

Osteoblast-like cells from estrogen receptor alpha knockout mice have deficient responses to mechanical strain.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4809789

Skeletal unloading induces resistance to insulin-like growth factor-I (IGF-I) by inhibiting activation of the IGF-I signaling pathways

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4809789

Perturbations in Bone Formation and Resorption in Insulin-Like Growth Factor Binding Protein-3 Transgenic Mice

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4809789

Skeletal unloading induces resistance to insulin-like growth factor I on bone formation.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4809789

Bone formation in the context of growth retardation induced by hIGFBP-1 overexpression in transgenic mice.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4809789

Insulin-like growth factor-binding protein-2 (IGFBP-2) overexpression negatively regulates bone size and mass, but not density, in the absence and presence of growth hormone/IGF-I excess in transgenic mice.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4809789

Effects of liver-derived insulin-like growth factor I on bone metabolism in mice.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4809789

Body composition, bone mass and microstructural analysis in GH-transgenic mice reveals that skeletal changes are specific to bone compartment and gender.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4809789

The skeletal structure of insulin-like growth factor I-deficient mice

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4809789

Experimental IGF-I receptor deficiency generates a sexually dimorphic pattern of organ-specific growth deficits in mice, affecting fat tissue in particular.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4809789

Phenotypic manifestations of insulin-like growth factor-binding protein-3 overexpression in transgenic mice

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4809789

Roles of growth hormone and insulin-like growth factor 1 in mouse postnatal growth.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4809789

ATP activates DNA synthesis by acting on P2X receptors in human osteoblast-like MG-63 cells.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4809789

Dysregulation of the insulin/IGF binding protein-1 axis in transgenic mice is associated with hyperinsulinemia and glucose intolerance.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4809789

Overexpression of insulin-like growth factor-binding protein-2 in transgenic mice reduces postnatal body weight gain.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4809789

Igf1 promotes longitudinal bone growth by insulin-like actions augmenting chondrocyte hypertrophy.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4809789

Effects of Igf1 gene deletion on postnatal growth patterns.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4809789

Human growth hormone transgene expression increases the biomechanical structural properties of mouse vertebrae.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4809789

Bone and hormonal changes induced by skeletal unloading in the mature male rat.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4809789

Elevated levels of growth hormone increase bone mineral content in normal young mice, but not in ovariectomized mice.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4809789

Mechanical strain-induced NO production by bone cells: a possible role in adaptive bone (re)modeling?

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4809789

Cellular patterns of insulin-like growth factor system gene expression in murine chondrogenesis and osteogenesis.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4809789

Growth retardation and hyperglycemia in insulin-like growth factor binding protein-1 transgenic mice.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4809789

Human insulin-like growth factor-binding protein-1 (hIGFBP-1) in transgenic mice: characterization and insights into the regulation of IGFBP-1 expression.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4809789

A targeted partial invalidation of the insulin-like growth factor I receptor gene in mice causes a postnatal growth deficit

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4809789

Expression of metallothionein-human growth hormone fusion genes in transgenic mice results in disproportionate skeletal gigantism

20 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4809789

Dramatic Pituitary Hyperplasia in Transgenic Mice Expressing a Human Growth Hormone-Releasing Factor Gene

20 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4809789

Loss of signal transducer and activator of transcription 5 leads to hepatosteatosis and impaired liver regeneration

4 December 2018

1 reference

12 December 2020

Local expression of human growth hormone in bone results in impaired mechanical integrity in the skeletal tissue of transgenic mice

1 reference

12 December 2020

Differential expression of insulin-like growth factor-I (IGF-I) and IGF-II messenger ribonucleic acid in growing rat bone

1 reference

12 December 2020

A novel ligand-independent function of the estrogen receptor is essential for osteocyte and osteoblast mechanotransduction

1 reference

12 December 2020

Effect of strain on bone nodule formation by rat osteogenic cells in vitro

1 reference

12 December 2020

Osteocytic expression of mRNA for c-fos and IGF-I: an immediate early gene response to an osteogenic stimulus

1 reference

12 December 2020

Sensitivity of osteocytes to biomechanical stress in vitro

1 reference

12 December 2020

Mechanical loading thresholds for lamellar and woven bone formation

1 reference

12 December 2020

Targeted overexpression of insulin-like growth factor I to osteoblasts of transgenic mice: increased trabecular bone volume without increased osteoblast proliferation

1 reference

12 December 2020

Stem cell antigen-1 positive cell-based systemic human growth hormone gene transfer strategy increases endosteal bone resorption and bone loss in mice

1 reference

12 December 2020

Expression of functional growth hormone receptors in cultured human osteoblast-like cells

1 reference

12 December 2020

Differential Effects of Growth Hormone and Insulin-Like Growth Factor I on Colony Formation of Epiphyseal Chondrocytes in Suspension Culture in Rats of Different Ages*

1 reference

12 December 2020

Growth enhancement of transgenic mice expressing human insulin-like growth factor I

1 reference

12 December 2020

Congenic Mice Providein VivoEvidence for a Genetic Locus that Modulates Serum Insulin-Like Growth Factor-I and Bone Acquisition

1 reference

12 December 2020

The temporal response of bone to unloading

1 reference

12 December 2020

The adaptive response of bone to mechanical loading in female transgenic mice is deficient in the absence of oestrogen receptor-alpha and -beta

1 reference

12 December 2020

Regulation by GH of insulin-like growth factor-I mRNA expression in rat epiphyseal growth plate as studied with in-situ hybridization

1 reference

12 December 2020

1 reference

12 December 2020

Osteoblast-specific knockout of the insulin-like growth factor (IGF) receptor gene reveals an essential role of IGF signaling in bone matrix mineralization

1 reference

12 December 2020

Effects of growth hormone and insulin-like growth factor-I on colony formation of rabbit epiphyseal chondrocytes at different stages of maturation

1 reference

12 December 2020

Strain gradients correlate with sites of periosteal bone formation

1 reference

12 December 2020

Insulin-Like Growth Factor-Independent Effects of Growth Hormone on Growth Plate Chondrogenesis and Longitudinal Bone Growth

1 reference

12 December 2020

Strain gradients correlate with sites of exercise-induced bone-forming surfaces in the adult skeleton

1 reference

12 December 2020

Transgenic mice overexpressing insulin-like growth factor binding protein-5 display transiently decreased osteoblastic function and osteopenia

1 reference

12 December 2020

Regulation of bone mass by mechanical strain magnitude

1 reference

12 December 2020

Demonstration of growth hormone receptors in cultured rat epiphyseal chondrocytes by specific binding of growth hormone and immunohistochemistry

1 reference

12 December 2020

Suppression of prostaglandin synthesis with NS-398 has different effects on endocortical and periosteal bone formation induced by mechanical loading

1 reference

12 December 2020

The CCAAT/enhancer-binding protein-alpha is expressed in the germinal layer of the growth plate: colocalisation with the growth hormone receptor

1 reference

12 December 2020

Mechanical strain stimulates nitric oxide production by rapid activation of endothelial nitric oxide synthase in osteocytes

1 reference

12 December 2020

Early responses to dynamic strain change and prostaglandins in bone-derived cells in culture

1 reference

12 December 2020

The influence of strain rate on adaptive bone remodelling

1 reference

12 December 2020

Systemic over-secretion of growth hormone in transgenic mice results in a specific pattern of skeletal modeling and adaptation

1 reference

12 December 2020

Selective osteoblast overexpression of IGF-I in mice prevents low protein-induced deterioration of bone strength and material level properties

1 reference

12 December 2020

10.1016/J.GHIR.2015.09.004

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26432542%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26432542%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

1 reference