Sir2 mediates apoptosis through JNK-dependent pathways in Drosophila (Q36735256)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18562277%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

title

Sir2 mediates apoptosis through JNK-dependent pathways in Drosophila (English)

1 reference

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9 January 2020

main subject

Drosophila

0 references

Sirtuin 2 Dmel_CG5085

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GOA release 2020-03-11

Sirtuin 1 Dmel_CG5216

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GOA release 2020-03-11

1 reference

5

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9 January 2020

author name string

Anthony J Griswold

1

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9 January 2020

Karen T Chang

2

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9 January 2020

Alexander P Runko

3

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9 January 2020

Melanie A Knight

4

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9 January 2020

language of work or name

English

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publication date

17 June 2008

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18562277%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

9 January 2020

published in

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9 January 2020

volume

105

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9 January 2020

issue

25

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9 January 2020

page(s)

8673-8678

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Effects of resveratrol on lifespan in Drosophila melanogaster and Caenorhabditis elegans

9 January 2020

cites work

1 reference

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29 September 2017

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Foxo and Fos regulate the decision between cell death and survival in response to UV irradiation.

29 September 2017

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Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha

29 September 2017

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Resveratrol improves health and survival of mice on a high-calorie diet

29 September 2017

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Sir2 blocks extreme life-span extension.

29 September 2017

1 reference

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JNK extends life span and limits growth by antagonizing cellular and organism-wide responses to insulin signaling

29 September 2017

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Substrate-specific activation of sirtuins by resveratrol

29 September 2017

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Gene deletions by ends-in targeting in Drosophila melanogaster

29 September 2017

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Sir2 mediates longevity in the fly through a pathway related to calorie restriction

29 September 2017

1 reference

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Sirtuin activators mimic caloric restriction and delay ageing in metazoans

29 September 2017

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Mammalian SIRT1 represses forkhead transcription factors

29 September 2017

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Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase

29 September 2017

1 reference

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Drosophila melanogaster MNK/Chk2 and p53 regulate multiple DNA repair and apoptotic pathways following DNA damage

29 September 2017

1 reference

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Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan

29 September 2017

1 reference

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The Drosophila forkhead transcription factor FOXO mediates the reduction in cell number associated with reduced insulin signaling

29 September 2017

1 reference

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Expression of Drosophila FOXO regulates growth and can phenocopy starvation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2438412

The Drosophila melanogaster sir2+ gene is nonessential and has only minor effects on position-effect variegation.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2438412

A Drosophila homologue of Sir2 modifies position-effect variegation but does not affect life span

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2438412

Eiger, a TNF superfamily ligand that triggers the Drosophila JNK pathway

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2438412

Negative control of p53 by Sir2alpha promotes cell survival under stress

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2438412

Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2438412

Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2438412

The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2438412

A cloning method to identify caspases and their regulators in yeast: identification of Drosophila IAP1 as an inhibitor of the Drosophila caspase DCP-1.

29 September 2017

1 reference

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Expression of Drosophila glass protein and evidence for negative regulation of its activity in non-neuronal cells by another DNA-binding protein.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2438412

The SIR2 gene family, conserved from bacteria to humans, functions in silencing, cell cycle progression, and chromosome stability

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2438412

Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation

29 September 2017

1 reference

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Puckered, a Drosophila MAPK phosphatase, ensures cell viability by antagonizing JNK-induced apoptosis.

29 September 2017

1 reference

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Drosophila p53 binds a damage response element at the reaper locus

28 June 2018

1 reference

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Hyperactivation of the silencing proteins, Sir2p and Sir3p, causes chromosome loss

28 June 2018

1 reference

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Reiterative use of the EGF receptor triggers differentiation of all cell types in the Drosophila eye.

28 June 2018

1 reference

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Programmed cell death during Drosophila embryogenesis.

28 June 2018

1 reference

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Sirt1 regulates aging and resistance to oxidative stress in the heart

28 June 2018

1 reference

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A conditional pan-neuronal Drosophila model of spinocerebellar ataxia 7 with a reversible adult phenotype suitable for identifying modifier genes.

5 September 2018

1 reference

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Cytoskeleton proteins are modulators of mutant tau-induced neurodegeneration in Drosophila.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2438412

Individual histone deacetylases in Drosophila modulate transcription of distinct genes.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2438412

Reaper-mediated inhibition of DIAP1-induced DTRAF1 degradation results in activation of JNK in Drosophila.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2438412

Evolution of TNF signaling mechanisms: JNK-dependent apoptosis triggered by Eiger, the Drosophila homolog of the TNF superfamily

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2438412

Drosophila Sir2 is required for heterochromatic silencing and by euchromatic Hairy/E(Spl) bHLH repressors in segmentation and sex determination

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2438412

Expression of baculovirus P35 prevents cell death in Drosophila

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2438412

5 September 2018

Identifiers

DOI

10.1073/PNAS.0803837105

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18562277%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

0 references

1 reference

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9 January 2020

1 reference